Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SMUNUM_RS00335 Genome accession   NZ_AP014571
Coordinates   58087..59001 (+) Length   304 a.a.
NCBI ID   WP_286216844.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53087..64001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS00320 (SMNUM_0042) - 55418..55645 (+) 228 WP_226707783.1 phosphoribosylaminoimidazole carboxylase -
  SMUNUM_RS00325 (SMNUM_0043) purB 55697..56995 (+) 1299 WP_286216843.1 adenylosuccinate lyase -
  SMUNUM_RS00330 (SMNUM_0044) - 57015..57701 (+) 687 WP_024782098.1 DNA alkylation repair protein -
  SMUNUM_RS00335 (SMNUM_0045) comR 58087..59001 (+) 915 WP_286216844.1 helix-turn-helix domain-containing protein Regulator
  SMUNUM_RS00340 (SMNUM_0046) - 59535..61376 (-) 1842 WP_002266377.1 carbohydrate-binding domain-containing protein -
  SMUNUM_RS00345 (SMNUM_0047) ruvB 61711..62706 (+) 996 WP_002263402.1 Holliday junction branch migration DNA helicase RuvB -
  SMUNUM_RS00350 (SMNUM_0048) - 62744..63169 (+) 426 WP_002263403.1 low molecular weight protein-tyrosine-phosphatase -
  SMUNUM_RS00355 (SMNUM_0049) - 63234..63617 (+) 384 WP_011074470.1 membrane protein -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35193.34 Da        Isoelectric Point: 5.0116

>NTDB_id=65949 SMUNUM_RS00335 WP_286216844.1 58087..59001(+) (comR) [Streptococcus mutans LP13]
MLKDFGKKIKSLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAIYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSKKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKHDFVKQLIAVSNEIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide


Download         Length: 915 bp        

>NTDB_id=65949 SMUNUM_RS00335 WP_286216844.1 58087..59001(+) (comR) [Streptococcus mutans LP13]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCCGTCTGCCTTGATGA
ATCGCAGTTGTCAACACGGCAGTTGACCAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTATTTATATTG
CAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAAAATGTCGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGCGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAAAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTCTTAGAATTGAAAAAACATGATTTTGTTAAGCAGCTTATTGCTGTCAGCAATGAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(9-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

97.697

100

0.977
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.431

94.737

0.497
  comR Streptococcus pyogenes MGAS315

47.492

98.355

0.467
  comR Streptococcus pyogenes MGAS8232

47.02

99.342

0.467
  comR Streptococcus suis P1/7

42.475

98.355

0.418
  comR Streptococcus suis 05ZYH33

42.475

98.355

0.418
  comR Streptococcus suis D9

36.667

98.684

0.362

Multiple sequence alignment