Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ANG_RS02270 Genome accession   NZ_AP013072
Coordinates   425772..426512 (+) Length   246 a.a.
NCBI ID   WP_003038927.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 420772..431512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS02250 (ANG_0436) - 421777..422163 (+) 387 WP_003038936.1 VOC family protein -
  ANG_RS02255 (ANG_0437) - 422663..423808 (-) 1146 WP_025271613.1 cobalamin-independent methionine synthase II family protein -
  ANG_RS02260 (ANG_0438) - 424172..425002 (+) 831 WP_003038886.1 Cof-type HAD-IIB family hydrolase -
  ANG_RS02265 (ANG_0439) - 425002..425640 (+) 639 WP_003038917.1 SGNH/GDSL hydrolase family protein -
  ANG_RS02270 (ANG_0440) comE/blpR 425772..426512 (+) 741 WP_003038927.1 response regulator transcription factor Regulator
  ANG_RS11180 (ANG_0441) - 426534..426944 (+) 411 WP_003038906.1 hypothetical protein -
  ANG_RS02280 (ANG_0442) - 427021..427956 (+) 936 WP_020999450.1 IS30 family transposase -
  ANG_RS02285 (ANG_0443) - 428076..428900 (+) 825 WP_003037768.1 sensor histidine kinase -
  ANG_RS02290 (ANG_0444) - 429309..431423 (+) 2115 WP_003037735.1 GBS Bsp-like repeat-containing protein -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 29319.85 Da        Isoelectric Point: 8.4284

>NTDB_id=65503 ANG_RS02270 WP_003038927.1 425772..426512(+) (comE/blpR) [Streptococcus anginosus subsp. whileyi MAS624]
MITIFVLEDDFVQQSRMERTIKEVMKKNSWKYRRIHIYGKPNQLLESITERGSHQLFFLDIQIKNESKRGFEIAEEIRRK
DPNATIVFVTTHSEFMPIIFQYKVAALDFIDKGLDERAFSRHVEEAINTVIEKQGRTVIEDSFNFETSLAMVQVPFHNIL
YFETSPTIHKVILHTKNERMEFYARISEIEKVDKRLYKCHQSYVVNLENILKVDKENGKVYFEDNEYCLVSRMRLKGLID
RIKKLQ

Nucleotide


Download         Length: 741 bp        

>NTDB_id=65503 ANG_RS02270 WP_003038927.1 425772..426512(+) (comE/blpR) [Streptococcus anginosus subsp. whileyi MAS624]
ATGATAACTATTTTTGTACTAGAAGATGATTTTGTACAACAATCTAGAATGGAGAGGACGATAAAAGAGGTTATGAAGAA
AAATTCTTGGAAATATCGTCGTATTCATATTTATGGGAAACCCAATCAACTACTTGAATCTATTACAGAAAGAGGTTCAC
ATCAACTTTTCTTTTTAGATATTCAAATAAAAAATGAATCAAAAAGAGGGTTTGAGATTGCAGAAGAAATTCGAAGAAAA
GATCCAAATGCAACAATTGTATTTGTAACAACCCATTCAGAATTTATGCCTATAATTTTTCAGTATAAAGTTGCGGCTCT
CGACTTTATTGATAAAGGATTAGATGAAAGAGCGTTTTCTAGACATGTTGAAGAAGCTATCAATACTGTGATAGAAAAGC
AAGGTCGTACAGTTATTGAAGATTCATTTAATTTTGAAACTTCATTAGCTATGGTCCAAGTGCCGTTTCATAATATTTTA
TATTTTGAAACATCGCCAACGATTCATAAAGTTATTTTACATACAAAAAATGAGAGAATGGAGTTTTATGCTCGTATTTC
AGAAATTGAAAAAGTAGATAAAAGACTTTATAAATGTCATCAATCTTATGTGGTAAATCTTGAAAATATTTTAAAAGTGG
ATAAAGAAAATGGTAAAGTATATTTTGAAGATAATGAATATTGTTTAGTATCAAGGATGAGATTAAAAGGGTTGATAGAT
AGAATAAAAAAACTTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-120)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.282

97.967

0.512
  comE/comE1 Streptococcus equinus JB1

45.267

98.78

0.447
  comE/comE2 Streptococcus equinus JB1

39.837

100

0.398
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.885

99.187

0.366
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.885

99.187

0.366

Multiple sequence alignment