Detailed information NTG0064625

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SPYOHK_RS04225
• Genome accession: NZ_AFRY01000001
• Coordinates: 1016706..1017542 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes HKU QMH11M0907901
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1011706..1022542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYOHK_RS04245 (SPYOHK_04915)	-	1011925..1012917 (-)	993	WP_002989762.1	D-lactate dehydrogenase	-
SPYOHK_RS04240 (SPYOHK_04920)	-	1012932..1013498 (-)	567	Protein_958	PTS sugar transporter subunit IIC	-
SPYOHK_RS10055	-	1013538..1014395 (+)	858	Protein_959	LysR family transcriptional regulator	-
SPYOHK_RS04230 (SPYOHK_04930)	topA	1014470..1016599 (-)	2130	WP_002989768.1	type I DNA topoisomerase	-
SPYOHK_RS04225 (SPYOHK_04935)	dprA	1016706..1017542 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
SPYOHK_RS04220 (SPYOHK_04940)	-	1017607..1018398 (-)	792	WP_002989771.1	ribonuclease HII	-
SPYOHK_RS04215 (SPYOHK_04945)	ylqF	1018388..1019236 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
SPYOHK_RS04210 (SPYOHK_04950)	-	1019455..1019895 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
SPYOHK_RS04205 (SPYOHK_04955)	trhA	1019892..1020542 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
SPYOHK_RS04200 (SPYOHK_04960)	-	1020659..1021570 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
SPYOHK_RS04195 (SPYOHK_04965)	-	1021620..1022060 (-)	441	WP_002989779.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=64625 SPYOHK_RS04225 WP_002989770.1 1016706..1017542(-) (dprA) [Streptococcus pyogenes HKU QMH11M0907901]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=64625 SPYOHK_RS04225 WP_002989770.1 1016706..1017542(-) (dprA) [Streptococcus pyogenes HKU QMH11M0907901]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367