Detailed information NTG0646134

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: L1A13_RS06035
• Genome accession: NZ_CP090889
• Coordinates: 1188367..1189215 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705300.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain CH2439
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1183367..1194215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A13_RS06020 (L1A13_06020)	-	1183608..1183967 (-)	360	WP_001237219.1	YbaN family protein	-
L1A13_RS06025 (L1A13_06025)	topA	1184188..1186275 (-)	2088	WP_000179682.1	type I DNA topoisomerase	-
L1A13_RS06030 (L1A13_06030)	-	1186442..1187485 (-)	1044	WP_001812883.1	TIGR00341 family protein	-
L1A13_RS10410	-	1188062..1188184 (+)	123	WP_001814242.1	hypothetical protein	-
L1A13_RS06035 (L1A13_06035)	dprA/cilB/dalA	1188367..1189215 (-)	849	WP_000705300.1	DNA-processing protein DprA	Machinery gene
L1A13_RS06040 (L1A13_06040)	-	1189301..1189990 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
L1A13_RS06045 (L1A13_06045)	-	1190002..1190880 (-)	879	WP_000837618.1	DMT family transporter	-
L1A13_RS06050 (L1A13_06050)	licA	1190870..1191739 (-)	870	WP_000411215.1	choline kinase LicA	-
L1A13_RS06055 (L1A13_06055)	-	1191756..1192778 (-)	1023	WP_000609890.1	ribitol-5-phosphate dehydrogenase	-
L1A13_RS06060 (L1A13_06060)	-	1192783..1193490 (-)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31048.70 Da
• Isoelectric Point: 5.4047

>NTDB_id=646134 L1A13_RS06035 WP_000705300.1 1188367..1189215(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain CH2439]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDIFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=646134 L1A13_RS06035 WP_000705300.1 1188367..1189215(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain CH2439]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGCTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATATCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553
dprA	Staphylococcus aureus N315	37.102	100	0.372