Detailed information NTG0064597

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STRIC_RS09935
• Genome accession: NZ_AEUX02000007
• Coordinates: 430907..431812 (+)
• Length: 301 a.a.
• NCBI ID: WP_008090260.1
• Uniprot ID: -
• Organism: Streptococcus ictaluri 707-05
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 425907..436812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STRIC_RS09915 (STRIC_2050)	purD	426233..427495 (+)	1263	WP_008089900.1	phosphoribosylamine--glycine ligase	-
STRIC_RS09920 (STRIC_2051)	purE	427531..428019 (+)	489	WP_008089954.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
STRIC_RS09925 (STRIC_2052)	purK	428006..429097 (+)	1092	WP_008089612.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
STRIC_RS09930 (STRIC_2053)	purB	429482..430774 (+)	1293	WP_008089717.1	adenylosuccinate lyase	-
STRIC_RS09935 (STRIC_2054)	comR	430907..431812 (+)	906	WP_008090260.1	helix-turn-helix domain-containing protein	Regulator
STRIC_RS12465	comS	431899..431994 (+)	96	WP_200857386.1	quorum-sensing system DWW-type pheromone	Regulator
STRIC_RS09940 (STRIC_2055)	ruvB	432028..433032 (+)	1005	WP_083835444.1	Holliday junction branch migration DNA helicase RuvB	-
STRIC_RS09945 (STRIC_2056)	-	433232..433666 (+)	435	WP_008090238.1	low molecular weight protein-tyrosine-phosphatase	-
STRIC_RS09950 (STRIC_2057)	-	433704..434105 (+)	402	WP_008090358.1	MORN repeat-containing protein	-
STRIC_RS09955 (STRIC_2058)	-	434102..435880 (+)	1779	WP_008090122.1	acyltransferase family protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35682.20 Da
• Isoelectric Point: 4.8464

>NTDB_id=64597 STRIC_RS09935 WP_008090260.1 430907..431812(+) (comR) [Streptococcus ictaluri 707-05]
MLANFGEKVRTLRFEKKLTREELCGDESELSVRQLARIELGQSIPSLSKVAFIAKKLDVSVGFLTDGEDLELPKRFKELK
YLILRTPTYMDGDKLKTREAQFDEIFEDYYDQLPEVEQLVIDCLQSKFDVYQSGDINFGSPLIQEYINQISKNTKYQLND
LLIIDLYLTCAVVSNFSKYHFDLSLYQEFVNTILKSEEELLLEDLFMLNNILHTCLDVSIRLKDYLKVEQMLLLSQKIMS
RIQDFQKIPMYCMYYWKYALYHLNDFAKAKHFYEQSVMFTSLTNDNYLVKKLEKEWLKDNF

Nucleotide

• Length: 906 bp

>NTDB_id=64597 STRIC_RS09935 WP_008090260.1 430907..431812(+) (comR) [Streptococcus ictaluri 707-05]
ATGTTAGCTAATTTTGGGGAAAAGGTAAGAACACTTCGGTTTGAAAAGAAACTGACACGAGAAGAACTTTGTGGAGATGA
ATCAGAACTTTCGGTTCGTCAGCTTGCAAGAATTGAGTTAGGACAGTCGATTCCCAGTTTATCCAAAGTAGCTTTTATTG
CAAAAAAACTTGACGTTAGTGTAGGTTTTTTAACGGATGGTGAAGATTTGGAATTGCCTAAGCGTTTCAAAGAGTTGAAG
TACTTGATATTACGAACGCCAACTTATATGGATGGAGATAAACTCAAGACACGTGAGGCCCAATTTGATGAAATATTTGA
AGATTACTATGACCAATTGCCAGAAGTAGAACAATTGGTTATTGATTGTTTGCAGTCAAAATTTGATGTTTATCAGAGCG
GGGATATCAATTTTGGTTCACCGCTGATTCAAGAATATATTAATCAAATTAGTAAAAATACAAAATATCAGTTAAATGAT
TTATTGATTATAGATTTATACTTAACTTGTGCTGTAGTATCAAATTTTAGTAAATATCATTTTGATCTAAGTTTATATCA
GGAATTTGTAAATACTATTTTAAAAAGTGAAGAAGAATTACTGCTAGAAGATTTGTTCATGCTAAACAATATTTTGCATA
CTTGTTTGGATGTTTCCATAAGATTAAAAGATTACTTGAAGGTAGAACAAATGCTTCTGTTAAGTCAAAAAATCATGTCT
AGAATTCAAGACTTTCAAAAAATACCTATGTATTGCATGTATTATTGGAAATATGCTTTATATCATTTAAATGATTTTGC
AAAAGCAAAACATTTTTATGAGCAATCAGTGATGTTTACGAGTTTGACAAATGATAATTATTTAGTGAAAAAGTTAGAGA
AAGAATGGTTAAAAGATAATTTTTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (12-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	62.207	99.336	0.618
comR	Streptococcus pyogenes MGAS8232	51.505	99.336	0.512
comR	Streptococcus mutans UA159	49.667	99.668	0.495
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.965	94.684	0.435
comR	Streptococcus suis P1/7	38.462	99.336	0.382
comR	Streptococcus suis 05ZYH33	38.462	99.336	0.382