Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   - Genome accession   NZ_AEUX02000007
Coordinates   431899..431994 (+) Length   32 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus ictaluri 707-05     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context


Location: 426899..436994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRIC_RS09920 (STRIC_2051) purE 427531..428019 (+) 489 WP_008089954.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  STRIC_RS09925 (STRIC_2052) purK 428006..429097 (+) 1092 WP_008089612.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  STRIC_RS09930 (STRIC_2053) purB 429482..430774 (+) 1293 WP_008089717.1 adenylosuccinate lyase -
  STRIC_RS09935 (STRIC_2054) comR 430907..431812 (+) 906 WP_008090260.1 helix-turn-helix domain-containing protein Regulator
  STRIC_RS12465 comS 431899..431994 (+) 96 WP_200857386.1 quorum-sensing system DWW-type pheromone Regulator
  STRIC_RS09940 (STRIC_2055) ruvB 432028..433032 (+) 1005 WP_083835444.1 Holliday junction branch migration DNA helicase RuvB -
  STRIC_RS09945 (STRIC_2056) - 433232..433666 (+) 435 WP_008090238.1 low molecular weight protein-tyrosine-phosphatase -
  STRIC_RS09950 (STRIC_2057) - 433704..434105 (+) 402 WP_008090358.1 MORN repeat-containing protein -
  STRIC_RS09955 (STRIC_2058) - 434102..435880 (+) 1779 WP_008090122.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3887.63 Da        Isoelectric Point: 9.6272

>NTDB_id=573 431899..431994(+) (comS) [Streptococcus ictaluri 707-05]
MFKSYKYYFILAAIFMMKSAAFLSDKDWWNLG

Nucleotide


Download         Length: 96 bp        

>NTDB_id=573 431899..431994(+) (comS) [Streptococcus ictaluri 707-05]
ATGTTTAAATCTTATAAGTATTATTTCATTCTTGCAGCTATTTTTATGATGAAATCTGCAGCGTTTTTATCAGATAAAGA
CTGGTGGAATTTAGGC

XIP


This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

KDWWNLG


Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

54.839

96.875

0.531

  comS Streptococcus pyogenes MGAS315

43.75

100

0.438


Multiple sequence alignment