Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   L1A16_RS09595 Genome accession   NZ_CP090885
Coordinates   1860377..1861393 (-) Length   338 a.a.
NCBI ID   WP_238881034.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ND6401     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1855377..1866393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A16_RS10740 - 1855454..1855585 (-) 132 WP_000768904.1 hypothetical protein -
  L1A16_RS09555 (L1A16_09555) - 1855586..1856776 (-) 1191 WP_000167765.1 acetate kinase -
  L1A16_RS09560 (L1A16_09560) comYH 1856827..1857780 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  L1A16_RS09565 (L1A16_09565) - 1857841..1858435 (-) 595 Protein_1878 methyltransferase domain-containing protein -
  L1A16_RS09570 (L1A16_09570) comGG/cglG 1858572..1858985 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  L1A16_RS09575 (L1A16_09575) comGF/cglF 1858963..1859424 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  L1A16_RS09580 (L1A16_09580) comGE/cglE 1859387..1859689 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  L1A16_RS09585 (L1A16_09585) comGD/cglD 1859652..1860056 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  L1A16_RS09590 (L1A16_09590) comGC/cglC 1860049..1860375 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  L1A16_RS09595 (L1A16_09595) comGB/cglB 1860377..1861393 (-) 1017 WP_238881034.1 competence type IV pilus assembly protein ComGB Machinery gene
  L1A16_RS09600 (L1A16_09600) comGA/cglA/cilD 1861341..1862282 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  L1A16_RS09605 (L1A16_09605) - 1862358..1862723 (-) 366 WP_000286415.1 DUF1033 family protein -
  L1A16_RS09610 (L1A16_09610) - 1862874..1863932 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  L1A16_RS09615 (L1A16_09615) nagA 1864095..1865246 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38500.51 Da        Isoelectric Point: 9.6162

>NTDB_id=645864 L1A16_RS09595 WP_238881034.1 1860377..1861393(-) (comGB/cglB) [Streptococcus pneumoniae strain ND6401]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDMAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=645864 L1A16_RS09595 WP_238881034.1 1860377..1861393(-) (comGB/cglB) [Streptococcus pneumoniae strain ND6401]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATATGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

94.379

100

0.944
  comYB Streptococcus gordonii str. Challis substr. CH1

70.238

99.408

0.698
  comYB Streptococcus mutans UA140

58.491

94.083

0.55
  comYB Streptococcus mutans UA159

58.491

94.083

0.55
  comGB Lactococcus lactis subsp. cremoris KW2

50.599

98.817

0.5