Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SPB_RS00450 Genome accession   NZ_AEUT02000001
Coordinates   75552..76262 (+) Length   236 a.a.
NCBI ID   WP_003102576.1    Uniprot ID   A0A1S1ZPR9
Organism   Streptococcus parauberis NCFD 2020     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 70552..81262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPB_RS00425 (SPB_0087) - 71287..72309 (+) 1023 WP_003105201.1 DUF3114 domain-containing protein -
  SPB_RS00430 (SPB_0088) - 72317..72964 (-) 648 WP_003104005.1 amino acid ABC transporter permease -
  SPB_RS00435 (SPB_0089) - 72979..73683 (-) 705 WP_003104614.1 amino acid ABC transporter permease -
  SPB_RS00440 (SPB_0090) - 73697..74512 (-) 816 WP_003105408.1 transporter substrate-binding domain-containing protein -
  SPB_RS00445 (SPB_0091) - 74525..75304 (-) 780 WP_003102773.1 amino acid ABC transporter ATP-binding protein -
  SPB_RS00450 (SPB_0092) vicR 75552..76262 (+) 711 WP_003102576.1 response regulator YycF Regulator
  SPB_RS00455 (SPB_0093) vicK 76255..77616 (+) 1362 WP_003103813.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SPB_RS00460 (SPB_0094) vicX 77621..78430 (+) 810 WP_037619792.1 MBL fold metallo-hydrolase Regulator
  SPB_RS00465 (SPB_0095) rnc 78528..79220 (+) 693 WP_003103277.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26995.82 Da        Isoelectric Point: 4.9038

>NTDB_id=64528 SPB_RS00450 WP_003102576.1 75552..76262(+) (vicR) [Streptococcus parauberis NCFD 2020]
MKKVLIVDDEKPISDIIKFNLTKEGYDTITAFDGREAVTAFEEEKPDLVILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENAISGTQELTIGNLQILPDAFVAKKYGNEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKAHD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=64528 SPB_RS00450 WP_003102576.1 75552..76262(+) (vicR) [Streptococcus parauberis NCFD 2020]
ATGAAAAAAGTTCTGATTGTCGATGATGAAAAGCCAATTTCAGATATCATCAAATTCAATTTAACAAAAGAAGGGTATGA
TACAATTACTGCCTTTGATGGGCGTGAAGCTGTAACTGCTTTTGAAGAAGAAAAACCTGACTTAGTTATTCTCGACTTAA
TGCTTCCTGAGTTGGATGGTCTTGAAGTAGCTAAGGAAATTCGCAAAACAAGTCATATCCCTATTATTATGCTTTCTGCT
AAAGATAGTGAATTTGATAAAGTTATTGGGCTTGAAATCGGTGCAGATGACTATGTGACCAAACCTTTTTCAAATCGTGA
ATTATTAGCCCGTGTAAAAGCTCATTTACGAAGAACTGAGACGATTGAAACAGCAGTCGCAGAGGAAAATGCTATCTCTG
GTACACAAGAATTAACTATCGGAAATTTACAAATTCTTCCGGATGCCTTTGTTGCCAAAAAATATGGTAATGAAGTTGAG
CTTACCCATCGTGAATTTGAATTGTTGCATCATTTAGCAAATCACATTGGTCAAGTTATGACTCGTGAGCACCTGCTTGA
AACGGTTTGGGGTTATGATTATTTTGGCGATGTTCGAACTGTCGATGTAACTGTTCGTCGTTTGAGAGAAAAAATTGAAG
ATACGCCTAGCCGTCCTGAATACATTTTGACAAGACGTGGTGTTGGCTATTATATGAAGGCACATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S1ZPR9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.407

100

0.894
  micA Streptococcus pneumoniae Cp1015

77.872

99.576

0.775
  covR Streptococcus salivarius strain HSISS4

43.348

98.729

0.428
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.103

98.305

0.424
  scnR Streptococcus mutans UA159

36.975

100

0.373

Multiple sequence alignment