Detailed information NTG0064525

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HMPREF9320_RS01515
• Genome accession: NZ_AENS01000008
• Coordinates: 25779..26684 (-)
• Length: 301 a.a.
• NCBI ID: WP_007891754.1
• Uniprot ID: G5KAF4
• Organism: Streptococcus pseudoporcinus SPIN 20026
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 20779..31684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9320_RS01495 (HMPREF9320_0033)	-	21480..23258 (-)	1779	WP_007891756.1	acyltransferase family protein	-
HMPREF9320_RS01500 (HMPREF9320_0034)	-	23255..23656 (-)	402	WP_007891657.1	membrane protein	-
HMPREF9320_RS01505 (HMPREF9320_0035)	-	23665..24108 (-)	444	WP_007891874.1	low molecular weight protein-tyrosine-phosphatase	-
HMPREF9320_RS01510 (HMPREF9320_0036)	ruvB	24578..25576 (-)	999	WP_007891873.1	Holliday junction branch migration DNA helicase RuvB	-
HMPREF9320_RS10660	comS	25611..25706 (-)	96	WP_198920371.1	quorum-sensing system DWW-type pheromone	Regulator
HMPREF9320_RS01515 (HMPREF9320_0037)	comR	25779..26684 (-)	906	WP_007891754.1	helix-turn-helix transcriptional regulator	Regulator
HMPREF9320_RS01520 (HMPREF9320_0038)	purB	26787..28079 (-)	1293	WP_007891752.1	adenylosuccinate lyase	-
HMPREF9320_RS01525 (HMPREF9320_0039)	-	28118..28546 (-)	429	WP_007892002.1	GNAT family N-acetyltransferase	-
HMPREF9320_RS10605	-	28510..28734 (-)	225	WP_162097551.1	hypothetical protein	-
HMPREF9320_RS01530 (HMPREF9320_0040)	-	29695..30312 (+)	618	WP_007891751.1	hypothetical protein	-
HMPREF9320_RS01535 (HMPREF9320_0041)	-	30433..31524 (+)	1092	WP_007891648.1	CHAP domain-containing protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35913.80 Da
• Isoelectric Point: 8.2451

>NTDB_id=64525 HMPREF9320_RS01515 WP_007891754.1 25779..26684(-) (comR) [Streptococcus pseudoporcinus SPIN 20026]
MKKLGKKIQKLRLDKSLTRETICGDESELSIRQLARIEKGQSIPSLSKVLFIAKKLDLPVIELINPECLVLPKRYKELKY
LILRRPTYMNDQNLVDREAQFDEIFEDYYATLPEEEQLIIDLLQSRFDVYQSGDTNYGKELLREYISQIRKKKSYALNDI
FLIDLYLTCGMVSNFKEELFDKGNFDCFTNKLVLLEDKLELKDLFLLNNVLLTSIAVGISIKEYQKTRILLDVCRRIMTI
TQDFQRMPIYYMYEWKYTLFYMKDSQKAYYYYRQSLIFARTLTDSYLVNRLKTSWELDNQS

Nucleotide

• Length: 906 bp

>NTDB_id=64525 HMPREF9320_RS01515 WP_007891754.1 25779..26684(-) (comR) [Streptococcus pseudoporcinus SPIN 20026]
ATGAAAAAACTTGGGAAAAAGATTCAAAAATTGAGGTTAGACAAGAGCCTGACTCGTGAAACGATTTGTGGAGATGAGTC
AGAATTATCAATTCGACAGCTAGCTCGTATTGAAAAAGGGCAATCTATTCCTAGTTTATCTAAAGTCTTATTTATTGCGA
AAAAATTAGATTTACCTGTTATTGAACTTATTAATCCAGAATGTTTGGTTCTACCAAAACGTTATAAGGAACTTAAATAT
TTGATTCTTAGGCGACCAACCTACATGAATGATCAAAATTTAGTGGATCGCGAAGCTCAGTTTGATGAAATATTTGAAGA
TTATTACGCGACTTTACCTGAAGAAGAGCAGCTAATTATTGATTTATTACAGTCTCGGTTTGATGTCTACCAAAGTGGTG
ATACTAATTATGGTAAAGAATTACTCCGTGAATATATCAGCCAAATTCGTAAGAAAAAGAGTTACGCTTTAAATGATATT
TTTTTAATCGATCTTTACTTAACTTGTGGAATGGTTTCAAATTTCAAAGAAGAATTATTTGATAAGGGAAATTTTGATTG
TTTTACTAATAAATTAGTCCTTTTGGAAGATAAGTTAGAGTTAAAAGATCTCTTTTTACTAAACAACGTCCTTCTCACTT
CCATTGCCGTAGGGATTAGTATTAAAGAATATCAGAAAACAAGGATACTTTTGGATGTTTGTCGACGGATTATGACGATT
ACCCAAGACTTTCAGCGTATGCCTATTTACTATATGTACGAATGGAAATACACTTTATTTTATATGAAGGACTCCCAAAA
GGCTTATTATTACTATCGTCAATCCTTAATATTTGCACGGACACTAACAGATAGTTATCTTGTTAATCGTTTAAAAACAA
GTTGGGAATTAGATAATCAATCGTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

3D structure

• AlphaFold DB: G5KAF4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	50.671	99.003	0.502
comR	Streptococcus pyogenes MGAS8232	45.847	100	0.458
comR	Streptococcus mutans UA159	44.186	100	0.442
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.172	96.346	0.435
comR	Streptococcus suis P1/7	38.411	100	0.385
comR	Streptococcus suis 05ZYH33	38.411	100	0.385