Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   - Genome accession   NZ_AENS01000008
Coordinates   25611..25706 (-) Length   32 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus pseudoporcinus SPIN 20026     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context


Location: 20611..30706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9320_RS01495 (HMPREF9320_0033) - 21480..23258 (-) 1779 WP_007891756.1 acyltransferase family protein -
  HMPREF9320_RS01500 (HMPREF9320_0034) - 23255..23656 (-) 402 WP_007891657.1 membrane protein -
  HMPREF9320_RS01505 (HMPREF9320_0035) - 23665..24108 (-) 444 WP_007891874.1 low molecular weight protein-tyrosine-phosphatase -
  HMPREF9320_RS01510 (HMPREF9320_0036) ruvB 24578..25576 (-) 999 WP_007891873.1 Holliday junction branch migration DNA helicase RuvB -
  HMPREF9320_RS10660 comS 25611..25706 (-) 96 WP_198920371.1 quorum-sensing system DWW-type pheromone Regulator
  HMPREF9320_RS01515 (HMPREF9320_0037) comR 25779..26684 (-) 906 WP_007891754.1 helix-turn-helix transcriptional regulator Regulator
  HMPREF9320_RS01520 (HMPREF9320_0038) purB 26787..28079 (-) 1293 WP_007891752.1 adenylosuccinate lyase -
  HMPREF9320_RS01525 (HMPREF9320_0039) - 28118..28546 (-) 429 WP_007892002.1 GNAT family N-acetyltransferase -
  HMPREF9320_RS10605 - 28510..28734 (-) 225 WP_162097551.1 hypothetical protein -
  HMPREF9320_RS01530 (HMPREF9320_0040) - 29695..30312 (+) 618 WP_007891751.1 hypothetical protein -

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3702.48 Da        Isoelectric Point: 10.0082

>NTDB_id=572 25611..25706(-) (comS) [Streptococcus pseudoporcinus SPIN 20026]
MLKKHKYTLLLVGLFLASAALTMTDKDWWHIG

Nucleotide


Download         Length: 96 bp        

>NTDB_id=572 25611..25706(-) (comS) [Streptococcus pseudoporcinus SPIN 20026]
ATGCTTAAAAAACACAAATATACCTTATTGTTAGTCGGTCTTTTCTTGGCTAGCGCAGCATTAACTATGACGGACAAAGA
TTGGTGGCATATCGGA

XIP


This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

KDWWHIG


Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

43.75

100

0.438


Multiple sequence alignment