Detailed information NTG0064474

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NEISUBOT_RS06595
• Genome accession: NZ_ACEO02000007
• Coordinates: 23311..24501 (+)
• Length: 396 a.a.
• NCBI ID: WP_004520183.1
• Uniprot ID: A0A9W5IQC4
• Organism: Neisseria subflava NJ9703
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 18311..29501

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NEISUBOT_RS06580 (NEISUBOT_04568)	-	19091..19684 (+)	594	WP_004520180.1	DUF4390 domain-containing protein	-
NEISUBOT_RS06585 (NEISUBOT_04569)	-	19688..21814 (+)	2127	WP_004520181.1	sensor histidine kinase	-
NEISUBOT_RS06590 (NEISUBOT_04570)	-	21801..23075 (+)	1275	WP_004520182.1	sigma-54-dependent transcriptional regulator	-
NEISUBOT_RS06595 (NEISUBOT_04571)	dprA	23311..24501 (+)	1191	WP_004520183.1	DNA-processing protein DprA	Machinery gene
NEISUBOT_RS06600 (NEISUBOT_04572)	-	24526..24981 (+)	456	WP_004520184.1	DUF494 family protein	-
NEISUBOT_RS06605 (NEISUBOT_04573)	topA	25055..27361 (+)	2307	WP_004520185.1	type I DNA topoisomerase	-
NEISUBOT_RS11365	-	27475..27825 (-)	351	WP_079453718.1	hypothetical protein	-
NEISUBOT_RS06610 (NEISUBOT_04574)	rsmD	28192..28764 (+)	573	WP_004520186.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NEISUBOT_RS06615 (NEISUBOT_04575)	-	28887..29138 (+)	252	WP_003679513.1	YfhL family 4Fe-4S dicluster ferredoxin	-

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 42738.77 Da
• Isoelectric Point: 5.8419

>NTDB_id=64474 NEISUBOT_RS06595 WP_004520183.1 23311..24501(+) (dprA) [Neisseria subflava NJ9703]
MTENERFAWLQLAFTPYIGAESFLVLLQQFGSAQAALNAPADKIAALVRHKQAAESWRNADKRALAQQSAEAALQWEMQD
GCRLLLLQDDDFPEMLTQGITAPPVLFLRGNAELLHTPSAAMVGSRHATPQAMRIAKDFGRALSEKGIPVVSGMASGIDT
AAHQGALQADGGTIAVWGTGIDRIYPPSNKNLAYEIAERGLIVSEFPLDTRPFAGNFPRRNRLIAALSQLTLVVEAALES
GSLITAKLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILHECPQLLQNTPVPSYSINKTVKLKNDQTKHL
QPKTIADEPQRPSENLSAAPSTSALLEAMGYDPIHPDILAQQTNTAAADVYAQLLEYELDGIVAALPGGRYQRVKA

Nucleotide

• Length: 1191 bp

>NTDB_id=64474 NEISUBOT_RS06595 WP_004520183.1 23311..24501(+) (dprA) [Neisseria subflava NJ9703]
ATGACGGAAAACGAGCGTTTTGCTTGGTTGCAACTGGCATTTACGCCCTATATCGGCGCAGAAAGTTTTTTGGTGCTGTT
GCAGCAATTCGGTAGCGCACAAGCTGCCTTGAATGCGCCGGCAGACAAAATTGCCGCGTTGGTGCGCCATAAACAGGCAG
CCGAGTCGTGGCGTAATGCGGACAAACGGGCTTTGGCGCAGCAGTCTGCTGAAGCCGCTTTACAATGGGAAATGCAGGAC
GGTTGCCGTTTGTTGCTGCTGCAAGATGATGATTTCCCCGAAATGCTGACACAAGGCATTACCGCGCCGCCGGTCTTGTT
TTTACGCGGCAATGCAGAGCTGCTGCACACACCTTCTGCCGCGATGGTCGGCAGCCGCCATGCCACGCCGCAGGCAATGC
GAATTGCCAAAGATTTCGGTAGGGCGTTGAGCGAAAAAGGCATTCCCGTCGTATCGGGTATGGCTTCGGGTATCGATACC
GCCGCCCATCAGGGGGCATTGCAGGCAGATGGCGGCACCATCGCCGTCTGGGGAACCGGTATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCTTATGAAATTGCCGAAAGGGGATTGATTGTCAGCGAGTTCCCTTTAGATACGCGTCCGTTTG
CAGGCAACTTTCCGCGCCGCAACCGTTTGATTGCCGCATTATCGCAGCTGACATTGGTGGTCGAGGCGGCATTGGAATCT
GGCTCATTGATTACCGCCAAGCTGGCGGCAGAGATGGGGCGCGAAGTGATGGCGGTGCCCGGGTCGATAGACAATCCGCA
TAGCAAAGGCTGCCACAAGCTGATTAAAGACGGGGCAAAACTGGTGGAATGTCTGGACGATATTCTCCATGAGTGTCCGC
AGCTATTGCAAAATACGCCTGTTCCATCATATTCTATAAATAAGACGGTAAAACTGAAAAACGATCAAACCAAACATCTG
CAACCAAAAACAATAGCGGATGAACCGCAAAGGCCGTCTGAAAACCTATCTGCCGCCCCATCAACAAGCGCTTTATTGGA
AGCAATGGGTTACGACCCGATACATCCCGATATTTTGGCGCAACAAACCAATACGGCGGCGGCAGACGTGTACGCACAGC
TTTTGGAATACGAACTTGACGGTATCGTTGCCGCCTTGCCGGGCGGCCGTTATCAGCGTGTCAAAGCATGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (331-389)

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	77.02	100	0.77
dprA	Neisseria meningitidis MC58	77.02	100	0.77
dprA	Neisseria gonorrhoeae MS11	76.131	100	0.765
dprA	Neisseria gonorrhoeae strain FA1090	75.819	100	0.76
dprA	Vibrio cholerae strain A1552	37.817	99.495	0.376
dprA	Vibrio campbellii strain DS40M4	37.726	97.727	0.369
dprA	Glaesserella parasuis strain SC1401	43.027	85.101	0.366