Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   LV497_RS06295 Genome accession   NZ_CP090007
Coordinates   1375670..1377766 (+) Length   698 a.a.
NCBI ID   WP_245084227.1    Uniprot ID   -
Organism   Streptococcus salivarius strain SALI-10     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1370670..1382766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS06270 (LV497_06270) trkA 1370761..1372110 (-) 1350 WP_014633874.1 Trk system potassium transporter TrkA -
  LV497_RS06275 (LV497_06275) - 1372388..1372897 (+) 510 WP_118172046.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  LV497_RS06280 (LV497_06280) - 1373208..1373765 (+) 558 WP_037598980.1 ECF transporter S component -
  LV497_RS06285 (LV497_06285) - 1373768..1374418 (+) 651 WP_048673883.1 phosphatase PAP2 family protein -
  LV497_RS06290 (LV497_06290) comR 1374596..1375495 (+) 900 WP_245084224.1 XRE family transcriptional regulator Regulator
  LV497_RS06295 (LV497_06295) comA 1375670..1377766 (+) 2097 WP_245084227.1 peptide cleavage/export ABC transporter Regulator
  LV497_RS06300 (LV497_06300) - 1377876..1378208 (+) 333 WP_245084230.1 DUF805 domain-containing protein -
  LV497_RS06305 (LV497_06305) - 1378260..1379654 (-) 1395 WP_245084233.1 DUF4153 domain-containing protein -
  LV497_RS06310 (LV497_06310) - 1380060..1380575 (+) 516 WP_245084235.1 AmiS/UreI family transporter -
  LV497_RS06315 (LV497_06315) - 1380600..1380902 (+) 303 WP_002886558.1 urease subunit gamma -
  LV497_RS06320 (LV497_06320) - 1380914..1381225 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78351.32 Da        Isoelectric Point: 9.1873

>NTDB_id=640136 LV497_RS06295 WP_245084227.1 1375670..1377766(+) (comA) [Streptococcus salivarius strain SALI-10]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLAMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAIGHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKELLKVCQQADILKDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARGLLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVGRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=640136 LV497_RS06295 WP_245084227.1 1375670..1377766(+) (comA) [Streptococcus salivarius strain SALI-10]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTAGCTGCCTTAGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCCATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGACTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGATTGATTGCAGTCATTGTCTTACTGAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTGACAATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCCTACCGATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACATCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCAATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCCCTTATTTTACAAAATCAGTCACTTTTTGTGATGACACTCACGGTAGTTCCTCTTTATGTGTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAGAGACGGTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCTAAGTGGCAATTAACGCAGGATGGTTTAAAGACGGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGCCATGGAAGGACAGCTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCAAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCCTTTAAACAACTTGCTCTT
AAGGGTGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
TGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTAGCGAAAATGTTGTCGGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTGGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACTGGAACCATTTTAGAAAATCTGCTGTTAGGATTTGAAGGAGAAGTTGACGAGAAAGAGCTTCTTAAGGTTTGCCA
ACAAGCTGATATCTTAAAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAGGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTAGCGATAGCGAGGGGCCTCTTATCCAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTTCGTCAACATGTCGGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(167-436)

ABC transporter (ABC_tran)

(494-640)

Peptidase C39 family (Peptidase_C39)

(3-139)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.546

98.997

0.53
  comA Streptococcus gordonii str. Challis substr. CH1

53.017

99.713

0.529
  comA Streptococcus mitis NCTC 12261

53.111

98.997

0.526
  comA Streptococcus pneumoniae Rx1

52.967

98.997

0.524
  comA Streptococcus pneumoniae D39

52.967

98.997

0.524
  comA Streptococcus pneumoniae R6

52.967

98.997

0.524
  comA Streptococcus pneumoniae TIGR4

52.822

98.997

0.523
  comA/nlmT Streptococcus mutans UA159

50

98.854

0.494