Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LV497_RS02725 Genome accession   NZ_CP090007
Coordinates   687522..688217 (-) Length   231 a.a.
NCBI ID   WP_022496133.1    Uniprot ID   -
Organism   Streptococcus salivarius strain SALI-10     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 682522..693217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS02710 (LV497_02710) - 683333..683878 (-) 546 WP_013991031.1 GNAT family N-acetyltransferase -
  LV497_RS02715 (LV497_02715) - 683944..685206 (-) 1263 WP_084915391.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  LV497_RS02720 (LV497_02720) comEC/celB 685292..687532 (-) 2241 WP_073688088.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LV497_RS02725 (LV497_02725) comEA 687522..688217 (-) 696 WP_022496133.1 helix-hairpin-helix domain-containing protein Machinery gene
  LV497_RS02730 (LV497_02730) - 688326..689081 (-) 756 WP_022496132.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  LV497_RS02735 (LV497_02735) - 689211..690146 (+) 936 WP_245085209.1 polysaccharide deacetylase family protein -
  LV497_RS02740 (LV497_02740) - 690196..690960 (+) 765 WP_002884567.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  LV497_RS02745 (LV497_02745) - 690964..691233 (+) 270 WP_245085212.1 GIY-YIG nuclease family protein -
  LV497_RS02750 (LV497_02750) - 691289..692866 (-) 1578 WP_002891571.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24362.26 Da        Isoelectric Point: 4.7321

>NTDB_id=640104 LV497_RS02725 WP_022496133.1 687522..688217(-) (comEA) [Streptococcus salivarius strain SALI-10]
MKEKIIAYVKDNRLFVSVIALLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKDK
SKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVVYVATKDENLSVLGQSGTGQVSDKG
GQTSAKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLEKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=640104 LV497_RS02725 WP_022496133.1 687522..688217(-) (comEA) [Streptococcus salivarius strain SALI-10]
GTGAAGGAAAAGATTATAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTTTACTGATGGTGATTTTTTG
CTTCTTTCTATGGATGACTTGTGGTGCGGGCAACAGTATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCATCCAAACAAAGCTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTGAAAAGGATAAG
TCAAAAGTAACAGTAGATGTTAAGGGGGCTGTGGCTAATCCGGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTAACTGA
TGCCATCAAAGCCGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTGTTAACTTAGCTGCAAGCCTGTCGGACGAAG
AGGTTGTCTATGTGGCAACTAAGGATGAAAACCTTTCTGTTCTTGGTCAATCAGGAACTGGTCAGGTTTCTGACAAAGGA
GGGCAAACTAGTGCTAAGGATGGCAAAATTAACTTAAACACAGCGACTTCAGAGGAGTTGCAAACTATTTCTGGGATTGG
AGCTAAGCGTGCTGAGGATATCATTGCCTATCGTGAAAGTCATGGAGGTTTTCAATCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACTTTAGAAAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(168-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

91.775

100

0.918
  comEA/celA/cilE Streptococcus mitis SK321

42.358

99.134

0.42
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

41.228

98.701

0.407
  comEA/celA/cilE Streptococcus mitis NCTC 12261

40.789

98.701

0.403
  comEA/celA/cilE Streptococcus pneumoniae Rx1

40.789

98.701

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

40.789

98.701

0.403
  comEA/celA/cilE Streptococcus pneumoniae R6

40.789

98.701

0.403