Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   T15_RS00765 Genome accession   NC_022665
Coordinates   114970..116007 (+) Length   345 a.a.
NCBI ID   WP_256786938.1    Uniprot ID   -
Organism   Streptococcus suis T15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 109970..121007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  T15_RS00750 (T15_0115) - 112672..113037 (+) 366 WP_023369079.1 DUF1033 family protein -
  T15_RS00755 (T15_0116) - 113072..114022 (-) 951 WP_023369081.1 S66 peptidase family protein -
  T15_RS00760 (T15_0117) comYA 114108..115058 (+) 951 WP_023369082.1 competence type IV pilus ATPase ComGA Machinery gene
  T15_RS00765 (T15_0118) comYB 114970..116007 (+) 1038 WP_256786938.1 competence type IV pilus assembly protein ComGB Machinery gene
  T15_RS00770 (T15_0119) comYC 116009..116290 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  T15_RS00775 (T15_0120) comGD 116271..116678 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD -
  T15_RS00780 (T15_0121) comYE 116650..116943 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  T15_RS00785 (T15_0122) comGF/cglF 116930..117364 (+) 435 WP_023369086.1 competence type IV pilus minor pilin ComGF Machinery gene
  T15_RS00790 (T15_0123) comGG 117342..117752 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG -
  T15_RS00795 (T15_0124) comYH 117809..118762 (+) 954 WP_011922562.1 class I SAM-dependent methyltransferase Machinery gene
  T15_RS00800 (T15_0125) - 118812..119999 (+) 1188 WP_023369088.1 acetate kinase -
  T15_RS00805 (T15_0126) - 120314..120865 (+) 552 WP_023369090.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38906.84 Da        Isoelectric Point: 9.6074

>NTDB_id=63285 T15_RS00765 WP_256786938.1 114970..116007(+) (comYB) [Streptococcus suis T15]
MRKLIAFLQQDISVLGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSSLSLVAVLAGMVWFRKTSKIKAFSRLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=63285 T15_RS00765 WP_256786938.1 114970..116007(+) (comYB) [Streptococcus suis T15]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCAAGTTTGCTG
GCTGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATTCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTAGCGACCTATCCGATTATATTGC
TTGGTTTTCTGCTTTTGATTATGCTAGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACCGTG
CTGATCAATCATCTACCGACCATCTTTTTATCTCTAAGTAGCCTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACTAGCAAAATCAAAGCATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGTTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAATCGCAGCTTTTTCGTGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
CAAAACCTATGCCTTTTTCAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATTTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus mitis NCTC 12261

60.299

97.101

0.586
  comGB/cglB Streptococcus mitis SK321

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae Rx1

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae D39

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae R6

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae TIGR4

59.701

97.101

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

97.681

0.499

Multiple sequence alignment