Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | LQF73_RS10230 | Genome accession | NZ_CP088015 |
| Coordinates | 2067028..2069190 (-) | Length | 720 a.a. |
| NCBI ID | WP_068813212.1 | Uniprot ID | A0A2N5KWZ3 |
| Organism | Lactobacillus crispatus strain M247 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 2040711..2069193 | 2067028..2069190 | within | 0 |
Gene organization within MGE regions
Location: 2040711..2069193
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LQF73_RS10055 (LQF73_10005) | - | 2040711..2041604 (-) | 894 | WP_005718198.1 | C40 family peptidase | - |
| LQF73_RS10060 (LQF73_10010) | - | 2041774..2042517 (-) | 744 | WP_005726403.1 | C40 family peptidase | - |
| LQF73_RS10065 (LQF73_10015) | - | 2042786..2043334 (-) | 549 | WP_005722445.1 | C40 family peptidase | - |
| LQF73_RS10070 (LQF73_10020) | - | 2043505..2044047 (-) | 543 | WP_005718194.1 | guanylate kinase | - |
| LQF73_RS10075 (LQF73_10025) | - | 2044144..2044446 (+) | 303 | WP_005718193.1 | DUF2187 family protein | - |
| LQF73_RS10080 (LQF73_10030) | - | 2044532..2046040 (+) | 1509 | WP_005718192.1 | O-antigen ligase family protein | - |
| LQF73_RS10085 (LQF73_10035) | - | 2046095..2046718 (-) | 624 | WP_005722447.1 | LVIS_2131 family protein | - |
| LQF73_RS10090 (LQF73_10040) | - | 2046906..2048057 (-) | 1152 | WP_020993065.1 | RNA-guided endonuclease TnpB family protein | - |
| LQF73_RS10095 (LQF73_10045) | nrdI | 2048350..2048796 (+) | 447 | WP_005718188.1 | class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI | - |
| LQF73_RS10100 (LQF73_10050) | - | 2048799..2049734 (+) | 936 | WP_005718186.1 | ribonucleotide-diphosphate reductase subunit beta | - |
| LQF73_RS10105 (LQF73_10055) | - | 2049774..2050304 (-) | 531 | WP_005718185.1 | hypothetical protein | - |
| LQF73_RS10110 (LQF73_10060) | - | 2050616..2051794 (+) | 1179 | WP_005727505.1 | IS256 family transposase | - |
| LQF73_RS10115 (LQF73_10065) | - | 2051928..2052515 (+) | 588 | WP_005729079.1 | C39 family peptidase | - |
| LQF73_RS10120 (LQF73_10070) | - | 2052712..2053197 (-) | 486 | WP_005718183.1 | threonine/serine exporter family protein | - |
| LQF73_RS10125 (LQF73_10075) | - | 2053200..2053970 (-) | 771 | WP_005718182.1 | threonine/serine exporter family protein | - |
| LQF73_RS10130 (LQF73_10080) | - | 2053981..2055522 (-) | 1542 | WP_005718181.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| LQF73_RS10135 (LQF73_10085) | - | 2055536..2055913 (-) | 378 | WP_005718180.1 | hypothetical protein | - |
| LQF73_RS10140 (LQF73_10090) | - | 2056058..2056609 (+) | 552 | WP_005722451.1 | GNAT family N-acetyltransferase | - |
| LQF73_RS10145 (LQF73_10095) | - | 2056924..2057085 (+) | 162 | WP_005718177.1 | hypothetical protein | - |
| LQF73_RS10150 (LQF73_10100) | - | 2057099..2057482 (+) | 384 | WP_005718176.1 | PBECR4 domain-containing protein | - |
| LQF73_RS10155 (LQF73_10105) | - | 2057479..2058168 (-) | 690 | WP_005718174.1 | DUF554 domain-containing protein | - |
| LQF73_RS10160 (LQF73_10110) | - | 2058233..2059471 (-) | 1239 | WP_005718173.1 | LCP family protein | - |
| LQF73_RS10165 (LQF73_10115) | pepF | 2059639..2061435 (+) | 1797 | WP_005718172.1 | oligoendopeptidase F | Regulator |
| LQF73_RS10170 (LQF73_10120) | - | 2061587..2061802 (+) | 216 | WP_005723825.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| LQF73_RS10175 (LQF73_10125) | - | 2061806..2062213 (+) | 408 | WP_005723824.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| LQF73_RS10180 (LQF73_10130) | - | 2062327..2062602 (-) | 276 | WP_005723823.1 | bacteriocin immunity protein | - |
| LQF73_RS10185 (LQF73_10135) | - | 2062606..2062824 (-) | 219 | WP_005726358.1 | TIGR04139 family peptide modification target | - |
| LQF73_RS10190 (LQF73_10140) | - | 2062998..2063294 (-) | 297 | WP_005725464.1 | bacteriocin immunity protein | - |
| LQF73_RS10195 (LQF73_10145) | - | 2063310..2063570 (-) | 261 | WP_005726357.1 | thioredoxin domain-containing protein | - |
| LQF73_RS10200 (LQF73_10150) | - | 2063757..2064935 (+) | 1179 | WP_005727388.1 | IS256 family transposase | - |
| LQF73_RS10205 (LQF73_10155) | - | 2065113..2065259 (-) | 147 | WP_005723821.1 | hypothetical protein | - |
| LQF73_RS10210 (LQF73_10160) | - | 2065269..2065415 (-) | 147 | WP_005727423.1 | hypothetical protein | - |
| LQF73_RS10215 (LQF73_10165) | - | 2065718..2065993 (-) | 276 | WP_005723819.1 | bacteriocin immunity protein | - |
| LQF73_RS10220 (LQF73_10170) | - | 2066015..2066212 (-) | 198 | WP_005723817.1 | hypothetical protein | - |
| LQF73_RS10225 (LQF73_10175) | - | 2066379..2067017 (-) | 639 | WP_225520247.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| LQF73_RS10230 (LQF73_10180) | comA | 2067028..2069190 (-) | 2163 | WP_068813212.1 | peptide cleavage/export ABC transporter | Regulator |
Sequence
Protein
Download Length: 720 a.a. Molecular weight: 80952.45 Da Isoelectric Point: 9.5103
>NTDB_id=632441 LQF73_RS10230 WP_068813212.1 2067028..2069190(-) (comA) [Lactobacillus crispatus strain M247]
MGMLTYKSIYVPQIDETDCGAACLAMILKNYHSQVSIAHLRHIAKTNTEGTTALGLVKTAEKFNMDVQAVKADMSLFNMK
DIQYPFIVHVIKDGGLLHYYVVLKSTKRKIIVADPDPTSGIKKMSKKAFEKEWTGITLFMVPKADFKPVKEKKNNLLSLF
PYMFKQKKLVRNIILAALLMTLISICSSYFVQGLIDTYIPNGTFTTLSVLAIGLLIAYVFNSIFSYGQQFLLNVLGQRLS
IDLNLQYIKHIFELPMEFFTTRKTGEITSRFSDASRIIDALASTVISLFLDLSIVILMGIILAVQNMTLFLITLASLPLY
AIVILGFSKRFERLNNDQMESNAVVSSSIIEDIQGIETIKALNSEQVRYRKIDSQFVDYLKKAFKYSKTEAFQTALKTFI
RLSLNVIILWVGASVVMHNQMSIGELMAFNALLSYFIDPLQNIINLQPTLQAANVAQNRLNEVYLVQSEFKGKTSVNDSH
DLNGDINFSHVDYRYGYGEDVLKDINLTIKDNEKLTIVGMSGSGKSTMVKLLVDFFSPTKGKVTFNGHSTRSINKHVLRS
YVNYVPQTPYIFAGTIKENLLLGSRKNITEKEIEEACQIAEIKNDIEKLPLGFNTQLDENAKILSGGQKQRLTIARALLS
PAKVLIFDEATSGLDTITEKKVVDNLIRLKNKTVIFIAHRLAIAERTDNIVVLNQGQIVEQGNHSELMAKHGYYYDLVKS
MGMLTYKSIYVPQIDETDCGAACLAMILKNYHSQVSIAHLRHIAKTNTEGTTALGLVKTAEKFNMDVQAVKADMSLFNMK
DIQYPFIVHVIKDGGLLHYYVVLKSTKRKIIVADPDPTSGIKKMSKKAFEKEWTGITLFMVPKADFKPVKEKKNNLLSLF
PYMFKQKKLVRNIILAALLMTLISICSSYFVQGLIDTYIPNGTFTTLSVLAIGLLIAYVFNSIFSYGQQFLLNVLGQRLS
IDLNLQYIKHIFELPMEFFTTRKTGEITSRFSDASRIIDALASTVISLFLDLSIVILMGIILAVQNMTLFLITLASLPLY
AIVILGFSKRFERLNNDQMESNAVVSSSIIEDIQGIETIKALNSEQVRYRKIDSQFVDYLKKAFKYSKTEAFQTALKTFI
RLSLNVIILWVGASVVMHNQMSIGELMAFNALLSYFIDPLQNIINLQPTLQAANVAQNRLNEVYLVQSEFKGKTSVNDSH
DLNGDINFSHVDYRYGYGEDVLKDINLTIKDNEKLTIVGMSGSGKSTMVKLLVDFFSPTKGKVTFNGHSTRSINKHVLRS
YVNYVPQTPYIFAGTIKENLLLGSRKNITEKEIEEACQIAEIKNDIEKLPLGFNTQLDENAKILSGGQKQRLTIARALLS
PAKVLIFDEATSGLDTITEKKVVDNLIRLKNKTVIFIAHRLAIAERTDNIVVLNQGQIVEQGNHSELMAKHGYYYDLVKS
Nucleotide
Download Length: 2163 bp
>NTDB_id=632441 LQF73_RS10230 WP_068813212.1 2067028..2069190(-) (comA) [Lactobacillus crispatus strain M247]
ATGGGCATGTTAACGTATAAATCAATTTATGTTCCACAAATCGATGAAACAGACTGTGGTGCAGCTTGTTTAGCAATGAT
CTTAAAGAATTATCATTCTCAAGTATCAATAGCACATTTACGTCATATTGCTAAAACCAATACTGAAGGAACTACTGCTT
TAGGATTAGTTAAAACTGCGGAAAAATTCAATATGGATGTTCAAGCGGTAAAAGCAGATATGTCCTTATTCAATATGAAA
GATATTCAATATCCTTTTATTGTTCATGTGATAAAAGATGGAGGATTGTTACATTATTATGTAGTTCTTAAAAGTACTAA
AAGAAAAATAATCGTAGCCGATCCTGATCCTACTAGTGGAATTAAAAAAATGTCCAAAAAGGCGTTTGAAAAAGAGTGGA
CAGGTATTACATTGTTTATGGTGCCTAAGGCAGATTTTAAGCCTGTAAAGGAGAAAAAGAATAATCTATTATCATTATTC
CCTTATATGTTTAAACAGAAAAAGTTAGTTAGAAACATTATTTTAGCTGCTTTGCTGATGACACTGATTAGTATCTGTAG
CTCATATTTTGTACAAGGGTTGATTGATACATATATTCCTAACGGTACATTTACCACGTTATCTGTTTTAGCTATTGGGT
TATTGATTGCATATGTCTTTAACTCAATTTTTTCATATGGTCAGCAATTTTTATTGAATGTTTTGGGGCAGCGGTTATCA
ATCGATCTTAATTTACAATACATTAAGCATATTTTTGAATTACCGATGGAATTTTTTACTACCAGAAAAACTGGTGAGAT
TACTTCTCGTTTTTCTGATGCAAGTAGAATTATAGATGCATTGGCAAGTACGGTGATTTCATTATTCCTTGATCTTTCAA
TTGTAATTTTAATGGGTATAATTTTGGCGGTTCAAAACATGACATTGTTTTTGATTACGCTAGCTTCATTACCACTCTAT
GCTATTGTTATTCTCGGCTTTTCAAAAAGGTTTGAAAGATTAAATAATGACCAGATGGAAAGTAATGCGGTAGTTAGTTC
ATCAATTATTGAAGATATTCAAGGAATTGAGACGATTAAAGCATTAAACAGTGAACAAGTACGTTATCGAAAAATTGATA
GTCAGTTTGTTGATTATTTAAAAAAAGCTTTTAAGTATAGCAAAACAGAAGCTTTTCAAACTGCTTTGAAAACTTTTATT
AGATTATCACTGAATGTCATTATTCTTTGGGTGGGGGCAAGTGTTGTAATGCATAATCAGATGTCTATTGGTGAATTGAT
GGCATTTAATGCATTATTATCATATTTTATTGATCCATTACAAAATATTATTAACTTGCAACCTACACTTCAAGCTGCAA
ATGTAGCTCAGAATCGTTTAAATGAAGTTTATTTAGTTCAAAGTGAATTTAAGGGCAAAACTTCAGTTAATGATAGTCAT
GATTTAAATGGAGACATTAATTTCTCACATGTCGATTATCGTTATGGATATGGTGAAGATGTCTTAAAAGATATTAATTT
GACGATCAAAGATAATGAGAAATTAACTATTGTGGGAATGAGTGGATCAGGTAAGTCAACTATGGTTAAATTGTTGGTTG
ATTTTTTCAGTCCCACAAAAGGAAAAGTAACTTTTAATGGTCATTCGACTAGAAGTATAAATAAGCATGTTTTACGCTCA
TATGTGAATTATGTGCCACAAACTCCATATATTTTTGCAGGTACCATTAAAGAGAATCTTTTGTTGGGAAGTCGTAAGAA
TATAACTGAAAAAGAGATAGAAGAAGCTTGCCAAATCGCGGAGATAAAGAATGACATTGAAAAATTGCCATTAGGATTTA
ATACACAATTAGATGAAAATGCTAAGATTTTGTCAGGTGGTCAGAAGCAAAGATTAACAATTGCTAGGGCCTTACTTTCA
CCTGCTAAGGTATTGATTTTTGATGAAGCAACAAGTGGGCTTGATACAATTACTGAGAAAAAAGTGGTTGATAATTTAAT
TAGGTTAAAGAATAAAACTGTTATATTTATTGCGCATCGTTTAGCTATTGCTGAAAGAACTGACAATATTGTGGTATTGA
ATCAGGGTCAAATTGTAGAACAAGGTAATCACAGTGAATTAATGGCTAAACATGGGTATTATTATGATTTGGTGAAAAGC
TAG
ATGGGCATGTTAACGTATAAATCAATTTATGTTCCACAAATCGATGAAACAGACTGTGGTGCAGCTTGTTTAGCAATGAT
CTTAAAGAATTATCATTCTCAAGTATCAATAGCACATTTACGTCATATTGCTAAAACCAATACTGAAGGAACTACTGCTT
TAGGATTAGTTAAAACTGCGGAAAAATTCAATATGGATGTTCAAGCGGTAAAAGCAGATATGTCCTTATTCAATATGAAA
GATATTCAATATCCTTTTATTGTTCATGTGATAAAAGATGGAGGATTGTTACATTATTATGTAGTTCTTAAAAGTACTAA
AAGAAAAATAATCGTAGCCGATCCTGATCCTACTAGTGGAATTAAAAAAATGTCCAAAAAGGCGTTTGAAAAAGAGTGGA
CAGGTATTACATTGTTTATGGTGCCTAAGGCAGATTTTAAGCCTGTAAAGGAGAAAAAGAATAATCTATTATCATTATTC
CCTTATATGTTTAAACAGAAAAAGTTAGTTAGAAACATTATTTTAGCTGCTTTGCTGATGACACTGATTAGTATCTGTAG
CTCATATTTTGTACAAGGGTTGATTGATACATATATTCCTAACGGTACATTTACCACGTTATCTGTTTTAGCTATTGGGT
TATTGATTGCATATGTCTTTAACTCAATTTTTTCATATGGTCAGCAATTTTTATTGAATGTTTTGGGGCAGCGGTTATCA
ATCGATCTTAATTTACAATACATTAAGCATATTTTTGAATTACCGATGGAATTTTTTACTACCAGAAAAACTGGTGAGAT
TACTTCTCGTTTTTCTGATGCAAGTAGAATTATAGATGCATTGGCAAGTACGGTGATTTCATTATTCCTTGATCTTTCAA
TTGTAATTTTAATGGGTATAATTTTGGCGGTTCAAAACATGACATTGTTTTTGATTACGCTAGCTTCATTACCACTCTAT
GCTATTGTTATTCTCGGCTTTTCAAAAAGGTTTGAAAGATTAAATAATGACCAGATGGAAAGTAATGCGGTAGTTAGTTC
ATCAATTATTGAAGATATTCAAGGAATTGAGACGATTAAAGCATTAAACAGTGAACAAGTACGTTATCGAAAAATTGATA
GTCAGTTTGTTGATTATTTAAAAAAAGCTTTTAAGTATAGCAAAACAGAAGCTTTTCAAACTGCTTTGAAAACTTTTATT
AGATTATCACTGAATGTCATTATTCTTTGGGTGGGGGCAAGTGTTGTAATGCATAATCAGATGTCTATTGGTGAATTGAT
GGCATTTAATGCATTATTATCATATTTTATTGATCCATTACAAAATATTATTAACTTGCAACCTACACTTCAAGCTGCAA
ATGTAGCTCAGAATCGTTTAAATGAAGTTTATTTAGTTCAAAGTGAATTTAAGGGCAAAACTTCAGTTAATGATAGTCAT
GATTTAAATGGAGACATTAATTTCTCACATGTCGATTATCGTTATGGATATGGTGAAGATGTCTTAAAAGATATTAATTT
GACGATCAAAGATAATGAGAAATTAACTATTGTGGGAATGAGTGGATCAGGTAAGTCAACTATGGTTAAATTGTTGGTTG
ATTTTTTCAGTCCCACAAAAGGAAAAGTAACTTTTAATGGTCATTCGACTAGAAGTATAAATAAGCATGTTTTACGCTCA
TATGTGAATTATGTGCCACAAACTCCATATATTTTTGCAGGTACCATTAAAGAGAATCTTTTGTTGGGAAGTCGTAAGAA
TATAACTGAAAAAGAGATAGAAGAAGCTTGCCAAATCGCGGAGATAAAGAATGACATTGAAAAATTGCCATTAGGATTTA
ATACACAATTAGATGAAAATGCTAAGATTTTGTCAGGTGGTCAGAAGCAAAGATTAACAATTGCTAGGGCCTTACTTTCA
CCTGCTAAGGTATTGATTTTTGATGAAGCAACAAGTGGGCTTGATACAATTACTGAGAAAAAAGTGGTTGATAATTTAAT
TAGGTTAAAGAATAAAACTGTTATATTTATTGCGCATCGTTTAGCTATTGCTGAAAGAACTGACAATATTGTGGTATTGA
ATCAGGGTCAAATTGTAGAACAAGGTAATCACAGTGAATTAATGGCTAAACATGGGTATTATTATGATTTGGTGAAAAGC
TAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis NCTC 12261 |
55.602 |
99.167 |
0.551 |
| comA | Streptococcus pneumoniae Rx1 |
55.462 |
99.167 |
0.55 |
| comA | Streptococcus pneumoniae D39 |
55.462 |
99.167 |
0.55 |
| comA | Streptococcus pneumoniae R6 |
55.462 |
99.167 |
0.55 |
| comA | Streptococcus pneumoniae TIGR4 |
55.322 |
99.167 |
0.549 |
| comA | Streptococcus mitis SK321 |
55.182 |
99.167 |
0.547 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
54.342 |
99.167 |
0.539 |
| comA/nlmT | Streptococcus mutans UA159 |
54.173 |
98.194 |
0.532 |