Detailed information NTG0626475

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: N2A93_RS00355
• Genome accession: NZ_CP104046
• Coordinates: 54515..55432 (+)
• Length: 305 a.a.
• NCBI ID: WP_003107457.1
• Uniprot ID: A0ABP2SVA0
• Organism: Streptococcus parauberis strain KSP14
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 49515..60432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N2A93_RS00335 (N2A93_00335)	purD	50066..51328 (+)	1263	WP_003107463.1	phosphoribosylamine--glycine ligase	-
N2A93_RS00340 (N2A93_00340)	purE	51536..52024 (+)	489	WP_003107462.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
N2A93_RS00345 (N2A93_00345)	purK	52011..53096 (+)	1086	WP_003107461.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
N2A93_RS00350 (N2A93_00350)	purB	53106..54398 (+)	1293	WP_003107459.1	adenylosuccinate lyase	-
N2A93_RS00355 (N2A93_00355)	comR	54515..55432 (+)	918	WP_003107457.1	helix-turn-helix transcriptional regulator	Regulator
N2A93_RS00360 (N2A93_00360)	-	55498..55596 (+)	99	WP_199764314.1	quorum-sensing system DWW-type pheromone	-
N2A93_RS00365 (N2A93_00365)	ruvB	55731..56729 (+)	999	WP_003107456.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
N2A93_RS00370 (N2A93_00370)	-	56953..57381 (+)	429	WP_003107455.1	low molecular weight protein-tyrosine-phosphatase	-
N2A93_RS00375 (N2A93_00375)	-	57410..57811 (+)	402	WP_003105881.1	membrane protein	-
N2A93_RS00380 (N2A93_00380)	-	57808..59586 (+)	1779	WP_003107454.1	acyltransferase family protein	-

Sequence

Protein

• Length: 305 a.a.
• Molecular weight: 35766.83 Da
• Isoelectric Point: 9.0707

>NTDB_id=626475 N2A93_RS00355 WP_003107457.1 54515..55432(+) (comR) [Streptococcus parauberis strain KSP14]
MPELGDKIKAIRLGKKLTRESICGDETELSVRQLVRIEQNQSLPTLAKLVYLAKVLDIRLDKLINPKTISIPHDYLALKY
QIIRTPLYMNDQVMAIREGQFDAIFEKYYDYLPDEEKLIIDFLQSKFDVYQSGDANFGRPLLQDYIRQISKKKRYQINDI
FLIDLYLTCAIVSSFKAEFFDLDLYRRFLSKLLLMEKTLALSDLFLLNNVLLTCIDVGIRIGHFEVIQPALKASHRIMYK
VQDFQRLPIYCMHAWKNALFYTKSVKRGEDYFHQAQLFAKLIGDKNLEGKLAREWQKNLAESEKT

Nucleotide

• Length: 918 bp

>NTDB_id=626475 N2A93_RS00355 WP_003107457.1 54515..55432(+) (comR) [Streptococcus parauberis strain KSP14]
ATGCCAGAGCTCGGGGATAAAATCAAAGCTATTCGACTGGGAAAAAAGTTAACTAGAGAGTCTATTTGCGGTGATGAGAC
AGAATTGTCTGTGCGTCAATTGGTACGAATTGAGCAAAATCAATCTCTGCCTACTCTTGCAAAATTAGTTTATCTTGCTA
AAGTTCTAGATATTAGACTTGATAAGTTAATTAACCCAAAAACAATTTCAATCCCACATGATTATCTTGCCCTTAAATAT
CAAATTATCCGGACACCGTTGTATATGAATGATCAAGTTATGGCAATTAGAGAAGGGCAGTTTGATGCTATTTTTGAAAA
GTACTATGACTATTTGCCAGATGAAGAAAAACTCATTATTGATTTTTTACAATCTAAATTTGATGTCTATCAAAGTGGAG
ATGCAAATTTTGGCCGTCCCCTCTTACAAGATTACATCAGACAAATCAGTAAGAAAAAACGCTATCAAATTAATGATATC
TTCTTAATTGATCTCTATTTAACCTGTGCGATTGTCAGTTCTTTTAAAGCTGAGTTTTTTGACTTGGACCTTTATCGTCG
CTTTCTGTCCAAGTTATTGTTAATGGAGAAGACATTAGCCTTAAGTGATTTATTCTTACTTAATAATGTCCTTTTAACCT
GTATTGATGTTGGTATTAGGATAGGTCATTTTGAAGTCATTCAACCGGCTTTAAAGGCAAGTCATCGCATTATGTACAAG
GTTCAAGATTTCCAACGCCTGCCAATTTACTGCATGCATGCCTGGAAAAATGCTCTTTTTTATACTAAGTCTGTAAAAAG
AGGAGAGGATTACTTTCATCAGGCGCAGCTATTTGCCAAATTGATTGGTGATAAAAATTTGGAAGGGAAATTAGCTCGTG
AATGGCAAAAAAATTTGGCAGAAAGTGAAAAAACATGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	45.819	98.033	0.449
comR	Streptococcus mutans UA159	42.617	97.705	0.416
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	43.902	94.098	0.413
comR	Streptococcus pyogenes MGAS8232	39.799	98.033	0.39
comR	Streptococcus suis P1/7	37.374	97.377	0.364
comR	Streptococcus suis 05ZYH33	37.374	97.377	0.364