Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LOD77_RS04765 Genome accession   NZ_CP086728
Coordinates   928043..928714 (+) Length   223 a.a.
NCBI ID   WP_024392086.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SS20     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 923043..933714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOD77_RS04740 (LOD77_04730) - 924157..925437 (+) 1281 WP_274505875.1 lipopolysaccharide biosynthesis protein -
  LOD77_RS04745 (LOD77_04735) - 925497..926276 (+) 780 WP_274505876.1 glycosyltransferase family A protein -
  LOD77_RS04750 (LOD77_04740) - 926285..926983 (+) 699 WP_174846160.1 glycosyltransferase family 2 protein -
  LOD77_RS04755 (LOD77_04745) - 926983..927312 (+) 330 WP_174846159.1 DUF2304 domain-containing protein -
  LOD77_RS04760 (LOD77_04750) - 927569..927946 (+) 378 WP_274505877.1 hypothetical protein -
  LOD77_RS04765 (LOD77_04755) ciaR 928043..928714 (+) 672 WP_024392086.1 response regulator transcription factor Regulator
  LOD77_RS04770 (LOD77_04760) ciaH 928707..930080 (+) 1374 WP_274505879.1 HAMP domain-containing sensor histidine kinase Regulator
  LOD77_RS04775 (LOD77_04765) - 930167..931384 (+) 1218 WP_274505880.1 transglutaminase domain-containing protein -
  LOD77_RS04780 (LOD77_04770) rpsT 931418..931666 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  LOD77_RS04785 (LOD77_04775) coaA 931725..932645 (-) 921 WP_237396439.1 type I pantothenate kinase -
  LOD77_RS04790 (LOD77_04780) - 932721..933311 (+) 591 WP_171988423.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25198.82 Da        Isoelectric Point: 4.2459

>NTDB_id=626196 LOD77_RS04765 WP_024392086.1 928043..928714(+) (ciaR) [Streptococcus parasuis strain SS20]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVSTPVLITTA
KEGLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNTTTVNGQEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGENLQTLRSVGYILKNV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=626196 LOD77_RS04765 WP_024392086.1 928043..928714(+) (ciaR) [Streptococcus parasuis strain SS20]
ATGATTAAGATACTGTTGGTAGAAGACGATTTAAGCCTTTCTAATTCAGTCTTTGATTTTTTAGATGATTTTGCAGACGT
TATGCAAGTTTTTGATGGTGAAGAAGGTATTTACGAAGCGGAAACAGGGGTTTATGACTTAATTCTTTTAGATTTAATGT
TACCTGAGAAAGATGGTTTTCAAGTATTAAAAGAATTGCGTGAAAAAGGGGTTTCTACTCCCGTTCTGATTACGACAGCC
AAGGAAGGCCTAGAGGATAAAGGACATGGGTTTGAATTGGGTGCAGATGACTATCTCACAAAACCATTCTATTTAGAAGA
ACTCAAAATGCGTATTCAAGCCTTGTTAAAACGAGCAGGGAAGTTCAATGAAAATACTCTAACATACGGAGATGTTACTG
TCGACTTATCTACAAATACTACGACAGTCAATGGTCAAGAAGTAGAATTGTTAGGGAAAGAGTTCGATTTGTTGGTATAT
TTCTTACAGAATCAGAATGTGATTTTACCTAAAACACAGATTTTTGATCGTATTTGGGGATTTGATAGTGATACAACCAT
TTCAGTTGTTGAAGTTTACGTATCAAAAGTAAGGAAAAAATTGAAAGGAACCGCATTTGGAGAAAATCTTCAAACTCTTC
GTAGTGTCGGTTACATTTTGAAAAATGTCTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.238

100

0.892
  ciaR Streptococcus pneumoniae Rx1

88.789

100

0.888
  ciaR Streptococcus pneumoniae D39

88.789

100

0.888
  ciaR Streptococcus pneumoniae R6

88.789

100

0.888
  ciaR Streptococcus pneumoniae TIGR4

88.789

100

0.888
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.611

100

0.381
  vicR Streptococcus mutans UA159

35.043

100

0.368