Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   LOD77_RS04770 Genome accession   NZ_CP086728
Coordinates   928707..930080 (+) Length   457 a.a.
NCBI ID   WP_274505879.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SS20     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 923707..935080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOD77_RS04740 (LOD77_04730) - 924157..925437 (+) 1281 WP_274505875.1 lipopolysaccharide biosynthesis protein -
  LOD77_RS04745 (LOD77_04735) - 925497..926276 (+) 780 WP_274505876.1 glycosyltransferase family A protein -
  LOD77_RS04750 (LOD77_04740) - 926285..926983 (+) 699 WP_174846160.1 glycosyltransferase family 2 protein -
  LOD77_RS04755 (LOD77_04745) - 926983..927312 (+) 330 WP_174846159.1 DUF2304 domain-containing protein -
  LOD77_RS04760 (LOD77_04750) - 927569..927946 (+) 378 WP_274505877.1 hypothetical protein -
  LOD77_RS04765 (LOD77_04755) ciaR 928043..928714 (+) 672 WP_024392086.1 response regulator transcription factor Regulator
  LOD77_RS04770 (LOD77_04760) ciaH 928707..930080 (+) 1374 WP_274505879.1 HAMP domain-containing sensor histidine kinase Regulator
  LOD77_RS04775 (LOD77_04765) - 930167..931384 (+) 1218 WP_274505880.1 transglutaminase domain-containing protein -
  LOD77_RS04780 (LOD77_04770) rpsT 931418..931666 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  LOD77_RS04785 (LOD77_04775) coaA 931725..932645 (-) 921 WP_237396439.1 type I pantothenate kinase -
  LOD77_RS04790 (LOD77_04780) - 932721..933311 (+) 591 WP_171988423.1 class I SAM-dependent methyltransferase -
  LOD77_RS04795 (LOD77_04785) - 933308..934585 (+) 1278 WP_274505881.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51391.50 Da        Isoelectric Point: 5.1078

>NTDB_id=626197 LOD77_RS04770 WP_274505879.1 928707..930080(+) (ciaH) [Streptococcus parasuis strain SS20]
MSKRFIKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNIADESDSAESNSDTTNSPKNQKDDQLKLGYNTHVLLYSNDGVVVNPDNFTGLSDLSLDKKNLGEIKEATVDSTFGGSE
DYRYVTIELAPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISILASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLAVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIAEVPPSYFDEI
FENYMMIADENGKTVTVNNLIHQPIRTDKVLVKQLLTILFDNAMKYTEEDGAIQVTANIKDKLVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=626197 LOD77_RS04770 WP_274505879.1 928707..930080(+) (ciaH) [Streptococcus parasuis strain SS20]
ATGTCTAAGCGATTTATAAAAATCATTTCAACAGATAAATTTTCATTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACCGCCATTATTTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCTGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAT
GGAAATATTGCTGATGAAAGTGATTCTGCAGAATCTAATTCAGATACAACAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTACAATACACATGTATTACTCTATTCAAATGATGGTGTAGTCGTTAATCCAGATAACTTTACAGGAC
TTTCTGATTTATCCTTAGACAAGAAAAATTTAGGCGAAATAAAGGAAGCAACGGTTGATTCTACATTCGGGGGTTCAGAA
GATTATCGTTATGTTACTATTGAATTGGCGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCTATTGAGACGTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTGGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTAATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTTTAGCTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTTTGGAAAGTAGTGAGAGTATAGGATCAAGCCTAGAGGAAGTTCGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATCGCTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTGAGAATTACATGATGATTGCAGATGAAAATGGTAAAACAGTCACGGTTAATAATTTGATTCATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGAAGATGGCGCTATCC
AAGTGACAGCCAATATCAAAGATAAGTTAGTTTACTTTACGGTAGCAGACAATGGATTGGGTATCAGTGATAGCGATAAA
AAGAAAATTTTCGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTCGGTTTATCCTT
AGCCTTACAAATTTCCAATAGTTTGAAAGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTACCGAGATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae D39

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae R6

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae TIGR4

51.096

99.781

0.51
  ciaH Streptococcus mutans UA159

50.562

97.374

0.492