Detailed information NTG0621545

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: LK431_RS01205
• Genome accession: NZ_CP085951
• Coordinates: 232894..234237 (+)
• Length: 447 a.a.
• NCBI ID: WP_021034382.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain FDAARGOS_1561
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 227894..239237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK431_RS01180 (LK431_01180)	-	227956..230550 (-)	2595	WP_110430713.1	penicillin-binding protein 1A	-
LK431_RS01185 (LK431_01185)	comA	230649..231446 (+)	798	WP_110430714.1	pilus assembly protein PilM	Machinery gene
LK431_RS01190 (LK431_01190)	comB	231447..231956 (+)	510	WP_111695366.1	competence protein B	Machinery gene
LK431_RS01195 (LK431_01195)	comC	231953..232474 (+)	522	WP_111695365.1	competence protein C	Machinery gene
LK431_RS01200 (LK431_01200)	comD	232471..232884 (+)	414	WP_021034381.1	pilus assembly protein PilP	Machinery gene
LK431_RS01205 (LK431_01205)	comE	232894..234237 (+)	1344	WP_021034382.1	type IV pilus secretin PilQ	Machinery gene
LK431_RS01210 (LK431_01210)	tnpA	234234..234687 (+)	454	Protein_218	IS200/IS605 family transposase	-
LK431_RS01215 (LK431_01215)	-	234935..235621 (+)	687	WP_021034384.1	ComF family protein	-
LK431_RS01220 (LK431_01220)	nfuA	235697..236293 (+)	597	WP_021034385.1	Fe-S biogenesis protein NfuA	-
LK431_RS01225 (LK431_01225)	nudC	236361..237155 (+)	795	WP_021034386.1	NAD(+) diphosphatase	-
LK431_RS01230 (LK431_01230)	-	237191..237781 (+)	591	WP_021034387.1	YjaG family protein	-
LK431_RS01235 (LK431_01235)	-	237920..238192 (+)	273	WP_005630954.1	HU family DNA-binding protein	-

Sequence

Protein

• Length: 447 a.a.
• Molecular weight: 49516.68 Da
• Isoelectric Point: 6.7046

>NTDB_id=621545 LK431_RS01205 WP_021034382.1 232894..234237(+) (comE) [Haemophilus influenzae strain FDAARGOS_1561]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVIDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKWQVAGNLTTNEPHLESHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPHSVQNIKKLISEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVSYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide

• Length: 1344 bp

>NTDB_id=621545 LK431_RS01205 WP_021034382.1 232894..234237(+) (comE) [Haemophilus influenzae strain FDAARGOS_1561]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTCTGTTTTTGTTTACCCTTAATTGTTTTTGCTAATCCCAAAAC
TGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACATTAGAGCAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATAGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAGGCAAATG
GCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGAGAGCCATACAGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGACAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTCGTGATTCAAGATGAACCTCATTCTGTGCAAAATATCAAAAAACTAATTTCTGAAATGGATAAACCTATTGAGCA
GATTGCTATTGAAGCGCGTATTGTGACGATAACAGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACGGAAAATGCAAGACGAGTTGCGGGCAGTCTTGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACAACACCTGCTGGCTCGATAGCATTACAAGTCGCCAAAATTAATGGGCGATTGCTCGATTTAGAATT
GAGTGCGTTAGAGCGTGAAAATAATGTAGAAATTATCGCAAGCCCTCGCTTACTAACCACAAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTATATTGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGCGAGGCGGTG
CTTGGTTTGGAAGTCACACCACATATTTCTAAAGATAACAATATTTTACTTGATTTATTAGTGAGCCAAAACTCACCAGG
TTCTCGTGTTTCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTGTTTCACGACACAATTACGAAAAGCGAAGATAAGGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTCAGCAAAGAAAGCGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCGCATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAGCAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (123-187)

• Bacterial type II and III secretion system protein (Secretin) (269-429)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	95.955	99.553	0.955
comE	Haemophilus influenzae 86-028NP	95.73	99.553	0.953
comE	Glaesserella parasuis strain SC1401	52.941	95.078	0.503
pilQ	Vibrio campbellii strain DS40M4	42.959	93.736	0.403
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	42.233	92.17	0.389
pilQ	Vibrio cholerae strain A1552	42.233	92.17	0.389