Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   LK431_RS01190 Genome accession   NZ_CP085951
Coordinates   231447..231956 (+) Length   169 a.a.
NCBI ID   WP_111695366.1    Uniprot ID   -
Organism   Haemophilus influenzae strain FDAARGOS_1561     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 226447..236956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK431_RS01170 (LK431_01170) - 226563..226892 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  LK431_RS01175 (LK431_01175) - 227034..227879 (-) 846 WP_111695367.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  LK431_RS01180 (LK431_01180) - 227956..230550 (-) 2595 WP_110430713.1 penicillin-binding protein 1A -
  LK431_RS01185 (LK431_01185) comA 230649..231446 (+) 798 WP_110430714.1 pilus assembly protein PilM Machinery gene
  LK431_RS01190 (LK431_01190) comB 231447..231956 (+) 510 WP_111695366.1 competence protein B Machinery gene
  LK431_RS01195 (LK431_01195) comC 231953..232474 (+) 522 WP_111695365.1 competence protein C Machinery gene
  LK431_RS01200 (LK431_01200) comD 232471..232884 (+) 414 WP_021034381.1 pilus assembly protein PilP Machinery gene
  LK431_RS01205 (LK431_01205) comE 232894..234237 (+) 1344 WP_021034382.1 type IV pilus secretin PilQ Machinery gene
  LK431_RS01210 (LK431_01210) tnpA 234234..234687 (+) 454 Protein_218 IS200/IS605 family transposase -
  LK431_RS01215 (LK431_01215) - 234935..235621 (+) 687 WP_021034384.1 ComF family protein -
  LK431_RS01220 (LK431_01220) nfuA 235697..236293 (+) 597 WP_021034385.1 Fe-S biogenesis protein NfuA -

Sequence

Protein


Download         Length: 169 a.a.        Molecular weight: 19955.96 Da        Isoelectric Point: 9.3352

>NTDB_id=621542 LK431_RS01190 WP_111695366.1 231447..231956(+) (comB) [Haemophilus influenzae strain FDAARGOS_1561]
MSMNLLPWRTYQHQNRLRRLAFYIALFILLAINLTLAFSNLIEQQKQHLQAQQTSFEQLNQQLYKTAKKIEQLRSAVQVG
EILTSIPKEQVKKSLQLLSELPFQQGELNKFKQDAHNLSLEGLAQDQREFELIHQFLKKHFPNVKLSQFQPEQQSLYFLF
DVEQVGEDK

Nucleotide


Download         Length: 510 bp        

>NTDB_id=621542 LK431_RS01190 WP_111695366.1 231447..231956(+) (comB) [Haemophilus influenzae strain FDAARGOS_1561]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAACCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAACTTTGGCTTTTAGTAATTTAATTGAACAACAGAAACAACATTTGCAGGCGCAACAAA
CATCTTTTGAACAACTTAATCAGCAACTTTATAAAACCGCCAAGAAAATTGAACAGTTGCGTAGTGCAGTGCAGGTTGGC
GAAATTTTGACATCTATTCCTAAAGAGCAAGTAAAAAAGAGTTTACAGCTGCTAAGTGAATTACCTTTTCAGCAAGGAGA
ACTGAATAAATTTAAACAAGATGCTCATAACTTAAGTTTGGAAGGTCTCGCACAAGATCAAAGAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGCCAGTTTCAACCTGAACAACAGTCATTGTATTTTCTCTTT
GATGTGGAACAAGTTGGAGAAGATAAGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

86.826

98.817

0.858
  comB Haemophilus influenzae Rd KW20

85.629

98.817

0.846