Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LK431_RS00845 Genome accession   NZ_CP085951
Coordinates   161205..162425 (+) Length   406 a.a.
NCBI ID   WP_021035705.1    Uniprot ID   -
Organism   Haemophilus influenzae strain FDAARGOS_1561     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 156205..167425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK431_RS00825 (LK431_00825) corC 157168..158067 (-) 900 WP_021035700.1 CNNM family magnesium/cobalt transport protein CorC -
  LK431_RS00830 (LK431_00830) ampD 158699..159253 (-) 555 WP_021035702.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LK431_RS00835 (LK431_00835) pilA 159368..159817 (+) 450 WP_021035703.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LK431_RS00840 (LK431_00840) pilB 159814..161208 (+) 1395 WP_111695393.1 GspE/PulE family protein Machinery gene
  LK431_RS00845 (LK431_00845) pilC 161205..162425 (+) 1221 WP_021035705.1 type II secretion system F family protein Machinery gene
  LK431_RS00850 (LK431_00850) pilD 162422..163114 (+) 693 WP_041175383.1 prepilin peptidase Machinery gene
  LK431_RS00855 (LK431_00855) rho 163168..164430 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  LK431_RS00860 (LK431_00860) metJ 164678..164995 (+) 318 WP_021035707.1 met regulon transcriptional regulator MetJ -
  LK431_RS00865 (LK431_00865) cueR 165009..165395 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  LK431_RS00870 (LK431_00870) - 165472..165678 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  LK431_RS00875 (LK431_00875) - 165752..165958 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46331.46 Da        Isoelectric Point: 9.7232

>NTDB_id=621537 LK431_RS00845 WP_021035705.1 161205..162425(+) (pilC) [Haemophilus influenzae strain FDAARGOS_1561]
MTKKLFYYQASNALNQEQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFAFSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDFLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=621537 LK431_RS00845 WP_021035705.1 161205..162425(+) (pilC) [Haemophilus influenzae strain FDAARGOS_1561]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGGAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTTACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTGCAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCAACAATAACCGCAATATTGCTCTCAATATCTAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTCCTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGAAGCCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.537

100

0.975
  pilC Glaesserella parasuis strain SC1401

37.905

98.768

0.374