Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   LK431_RS00850 Genome accession   NZ_CP085951
Coordinates   162422..163114 (+) Length   230 a.a.
NCBI ID   WP_041175383.1    Uniprot ID   -
Organism   Haemophilus influenzae strain FDAARGOS_1561     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 157422..168114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK431_RS00830 (LK431_00830) ampD 158699..159253 (-) 555 WP_021035702.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LK431_RS00835 (LK431_00835) pilA 159368..159817 (+) 450 WP_021035703.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LK431_RS00840 (LK431_00840) pilB 159814..161208 (+) 1395 WP_111695393.1 GspE/PulE family protein Machinery gene
  LK431_RS00845 (LK431_00845) pilC 161205..162425 (+) 1221 WP_021035705.1 type II secretion system F family protein Machinery gene
  LK431_RS00850 (LK431_00850) pilD 162422..163114 (+) 693 WP_041175383.1 prepilin peptidase Machinery gene
  LK431_RS00855 (LK431_00855) rho 163168..164430 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  LK431_RS00860 (LK431_00860) metJ 164678..164995 (+) 318 WP_021035707.1 met regulon transcriptional regulator MetJ -
  LK431_RS00865 (LK431_00865) cueR 165009..165395 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  LK431_RS00870 (LK431_00870) - 165472..165678 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  LK431_RS00875 (LK431_00875) - 165752..165958 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  LK431_RS00880 (LK431_00880) - 165933..168101 (+) 2169 WP_041175384.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26754.82 Da        Isoelectric Point: 9.1329

>NTDB_id=621538 LK431_RS00850 WP_041175383.1 162422..163114(+) (pilD) [Haemophilus influenzae strain FDAARGOS_1561]
MIYFIMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNRSPFQPHFASIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIRLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=621538 LK431_RS00850 WP_041175383.1 162422..163114(+) (pilD) [Haemophilus influenzae strain FDAARGOS_1561]
ATGATTTATTTCATAATGTTTTTATTAGGCGGTATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACCGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGAGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGAGCAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCGTTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

96.957

100

0.97
  pilD Haemophilus influenzae Rd KW20

94.348

100

0.943