Detailed information NTG0061875

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SIR_RS13635
• Genome accession: NC_022246
• Coordinates: 776337..777179 (+)
• Length: 280 a.a.
• NCBI ID: WP_020998618.1
• Uniprot ID: T1ZFA2
• Organism: Streptococcus intermedius B196
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 771337..782179

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SIR_RS13610 (SIR_0759)	-	772926..773264 (+)	339	WP_003072637.1	ATP cone domain-containing protein	-
SIR_RS13615 (SIR_0760)	rpsU	773413..773589 (+)	177	WP_000048054.1	30S ribosomal protein S21	-
SIR_RS13620 (SIR_0761)	ylqF	773994..774845 (+)	852	WP_021002708.1	ribosome biogenesis GTPase YlqF	-
SIR_RS13625 (SIR_0762)	-	774832..775608 (+)	777	WP_021002709.1	ribonuclease HII	-
SIR_RS13630 (SIR_0763)	-	775697..776254 (+)	558	WP_021002710.1	sugar O-acetyltransferase	-
SIR_RS13635 (SIR_0764)	dprA/cilB/dalA	776337..777179 (+)	843	WP_020998618.1	DNA-processing protein DprA	Machinery gene
SIR_RS13640 (SIR_0765)	topA	777265..779358 (+)	2094	WP_112384696.1	type I DNA topoisomerase	-
SIR_RS13645 (SIR_0766)	-	779414..779908 (+)	495	WP_021002712.1	hypothetical protein	-
SIR_RS13650 (SIR_0767)	trmFO	780002..781336 (+)	1335	WP_021002713.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31115.65 Da
• Isoelectric Point: 5.6463

>NTDB_id=61875 SIR_RS13635 WP_020998618.1 776337..777179(+) (dprA/cilB/dalA) [Streptococcus intermedius B196]
MNNFDIYKLKEAGLTNQQVINVLEYAEIHEKDLSAKGMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIIKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGPEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCITSGSDVLSEFQF

Nucleotide

• Length: 843 bp

>NTDB_id=61875 SIR_RS13635 WP_020998618.1 776337..777179(+) (dprA/cilB/dalA) [Streptococcus intermedius B196]
ATGAATAATTTTGATATTTATAAATTAAAAGAAGCCGGCTTGACAAACCAACAAGTTATCAATGTATTAGAATATGCTGA
AATACATGAAAAAGATTTGTCTGCCAAAGGCATGGCAGTTGTTTCCGAATGCCGTAATCCTGCTCTTTTTATTGAAAAAT
ATTTGCAGTTAGATGATGATTTATTACGTCAAGAATTTGAGAAATTCCCATCCTTTTCTATCTTGGACGATGTATATCCT
TGGGATTTGAGTGAAATTTATAATCCACCCGTTCTTCTTTTTTATAAAGGTAATTTGGATTTGCTAAAATTACCTAAAGT
GGCTGTTGTAGGAAGTCGGAATAGTAGCCGAGTAGGCAGTCAATCTGTTCAAAAGATTATTAAAGAGCTAAACAATGAAT
TGGTTATTGTGAGTGGTTTAGCACGCGGAATTGATACCTCGGCTCACATGGCAGCGTTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGCCTAGATGTGTTTTACCCAAGGGCGAATAAGAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTGCTTAGTGAGTATGGTCCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GTAGAGGGGTTATTGTCGCTGAAGCTAAAATGCGCTCAGGCAGCCTTATTACTTGTGAGCGAGCAATGGAAGAAGGGCGA
GATGTATTTGCTATTCCAGGGTCAATTTTAGATGGAAGAAGTGATGGCTGTCATCATTTGATTCAGGAGGGAGCAAAATG
CATTACATCAGGGTCTGACGTACTTTCTGAATTCCAGTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-60)

3D structure

• AlphaFold DB: T1ZFA2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	76.429	100	0.764
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae D39	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae R6	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	76.071	100	0.761
dprA/cilB/dalA	Streptococcus mitis SK321	75.714	100	0.757
dprA	Streptococcus mutans UA159	65	100	0.65
dprA	Lactococcus lactis subsp. cremoris KW2	57.143	100	0.571
dprA	Legionella pneumophila strain ERS1305867	43.154	86.071	0.371
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75	0.361