Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SCR2_RS02825 Genome accession   NC_022245
Coordinates   552775..554925 (+) Length   716 a.a.
NCBI ID   WP_006267089.1    Uniprot ID   F9P4Z8
Organism   Streptococcus constellatus subsp. pharyngis C818     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 547775..559925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCR2_RS02810 (SCR2_0556) holA 550131..551168 (+) 1038 WP_006267208.1 DNA polymerase III subunit delta -
  SCR2_RS02815 (SCR2_0557) - 551239..551844 (+) 606 WP_006267096.1 superoxide dismutase -
  SCR2_RS02820 (SCR2_0558) - 551917..552291 (-) 375 WP_022525583.1 hypothetical protein -
  SCR2_RS02825 (SCR2_0559) comA/nlmT 552775..554925 (+) 2151 WP_006267089.1 peptide cleavage/export ABC transporter Regulator
  SCR2_RS02830 (SCR2_0560) - 554936..556296 (+) 1361 Protein_545 bacteriocin secretion accessory protein -
  SCR2_RS02835 (SCR2_0561) - 556393..556542 (+) 150 WP_003037249.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SCR2_RS10595 - 556587..557408 (-) 822 WP_235043796.1 sensor histidine kinase -
  SCR2_RS02845 (SCR2_0563) comE/blpR 557899..558645 (-) 747 WP_041786327.1 response regulator transcription factor Regulator
  SCR2_RS02850 (SCR2_0564) - 558814..559527 (-) 714 WP_020997680.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80343.96 Da        Isoelectric Point: 9.4725

>NTDB_id=61813 SCR2_RS02825 WP_006267089.1 552775..554925(+) (comA/nlmT) [Streptococcus constellatus subsp. pharyngis C818]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIILSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLFILIMVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSVVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLNKTFKLSKYSIMQTALKQGAQFI
LNVVILWVGASLAMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANNRLNEVYLVESEFKTKQVITEKNFLA
GDITFHNVSYKYGFGRDTLSDINLTIKIGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGTNQIFSQEEIIRACEIAEIRSDIEQIPMGYQTELSDGAGLSGGQKQRIALARALLTKSSI
LILDEATSGLDVLTEKKVIDNLIGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHTKLMERKGFYHHLFNK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=61813 SCR2_RS02825 WP_006267089.1 552775..554925(+) (comA/nlmT) [Streptococcus constellatus subsp. pharyngis C818]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTGGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCGCATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCACAAGAAATAGGCTTTGAGACACGACCGATTCAAGGGGATATGTCCTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTTTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGACGAATACATTCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTATACTTAGTCAGCGACTAACCATCGATGTA
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTTTATTTTGATAA
TGGTAGGAGGGGTACTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCCGTGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAAGTCGTTACCAAAAGATTGATAGTGAGTTTG
TCGATTATCTGAATAAGACTTTCAAGCTAAGTAAATATTCCATTATGCAGACAGCTCTCAAACAAGGAGCACAATTTATT
TTGAATGTTGTTATTCTATGGGTTGGAGCCTCTCTGGCTATGTCTCAAAAAATTTCGATTGGACAGCTGATTACTTTTAA
TGCACTCCTTTCGTATTTTACAAGTCCACTTGAAAGTATCATCAATCTGCAAACCAAGCTGCAATCGGCTAAGGTTGCCA
ACAATCGGTTGAATGAAGTCTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCATTACAGAGAAAAATTTCTTGGCT
GGTGATATTACGTTCCATAATGTTTCCTATAAGTACGGTTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AATAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGATCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAACCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATACCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCATCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATAGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAACGGACAAATCAAGTGATTGTTCTTGATAAAGGACAGA
TTATTGAAACTGGTTCCCACACTAAATTGATGGAAAGAAAAGGTTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(6-141)

ABC transporter transmembrane region (ABC_membrane)

(168-437)

ABC transporter (ABC_tran)

(499-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P4Z8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.073

99.022

0.714
  comA Streptococcus mitis NCTC 12261

65.919

99.581

0.656
  comA Streptococcus mitis SK321

65.778

99.581

0.655
  comA Streptococcus pneumoniae D39

65.498

99.581

0.652
  comA Streptococcus pneumoniae Rx1

65.498

99.581

0.652
  comA Streptococcus pneumoniae R6

65.498

99.581

0.652
  comA Streptococcus gordonii str. Challis substr. CH1

65.358

99.581

0.651
  comA Streptococcus pneumoniae TIGR4

65.077

99.581

0.648

Multiple sequence alignment