Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   SANR_RS05705 Genome accession   NC_022239
Coordinates   1149897..1150571 (-) Length   224 a.a.
NCBI ID   WP_003036714.1    Uniprot ID   -
Organism   Streptococcus anginosus C238     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1144897..1155571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS05690 (SANR_1117) - 1144932..1146545 (-) 1614 WP_020999625.1 M20/M25/M40 family metallo-hydrolase -
  SANR_RS05695 (SANR_1118) - 1146722..1148170 (+) 1449 WP_003036764.1 alpha-amylase -
  SANR_RS05700 (SANR_1119) ciaH 1148561..1149907 (-) 1347 WP_003036710.1 sensor histidine kinase Regulator
  SANR_RS05705 (SANR_1120) ciaR 1149897..1150571 (-) 675 WP_003036714.1 response regulator transcription factor Regulator
  SANR_RS05710 (SANR_1121) - 1150846..1151301 (-) 456 WP_003036769.1 hypothetical protein -
  SANR_RS05715 (SANR_1122) - 1151638..1152381 (-) 744 WP_003036850.1 alpha/beta fold hydrolase -
  SANR_RS05725 (SANR_1124) rplS 1152623..1152970 (-) 348 WP_003024326.1 50S ribosomal protein L19 -
  SANR_RS05730 (SANR_1125) - 1153120..1154079 (-) 960 WP_003036699.1 ROK family glucokinase -
  SANR_RS11895 - 1154353..1154649 (+) 297 WP_003036801.1 LysR family transcriptional regulator -
  SANR_RS11900 - 1154850..1155128 (+) 279 WP_003036789.1 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25373.03 Da        Isoelectric Point: 4.2408

>NTDB_id=61678 SANR_RS05705 WP_003036714.1 1149897..1150571(-) (ciaR) [Streptococcus anginosus C238]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLIMTA
KESLNDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLSYGDVTINLSTNTTLVDGNEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTTFANNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=61678 SANR_RS05705 WP_003036714.1 1149897..1150571(-) (ciaR) [Streptococcus anginosus C238]
ATGATTAAGATTCTATTAGTGGAAGACGACCTCGGTCTATCTAATTCAGTATTTGATTTTTTGGATGATTTTGCAGATGT
CATGCAAGTTTTTGACGGTGAGGAAGGATTGTACGAGGCTGAGAGTGGCGTGTACGACCTTATCTTGCTTGATCTGATGT
TGCCAGAAAAAGACGGTTTCCAAGTATTGAAAGAATTGCGTGAAAAAGGCGTTACCACACCTGTTTTGATTATGACAGCC
AAAGAAAGTTTGAATGATAAAGGACATGGTTTTGAACTGGGAGCTGACGATTATTTGACCAAACCATTTTATTTGGAAGA
GTTAAAAATGCGGATTCAAGCTCTTTTGAAACGATCGGGCAAGTTTAATGAAAATACTCTTTCTTATGGCGATGTCACTA
TTAATTTATCAACAAACACTACACTTGTAGACGGAAATGAAGTAGAATTGCTCGGAAAAGAATTTGACTTGCTGGTGTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCTAAGACACAGATTTTCGATCGCTTGTGGGGATTTGATAGTGATACAACGAT
TTCAGTTGTAGAAGTTTATGTCTCAAAAATCCGGAAAAAATTGAAAGGGACGACCTTTGCGAACAATCTTCAAACGCTTC
GTAGTGTCGGATATATTTTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

91.518

100

0.915
  ciaR Streptococcus pneumoniae D39

91.518

100

0.915
  ciaR Streptococcus pneumoniae R6

91.518

100

0.915
  ciaR Streptococcus pneumoniae TIGR4

91.518

100

0.915
  ciaR Streptococcus mutans UA159

89.686

99.554

0.893
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.207

100

0.397
  vicR Streptococcus mutans UA159

36.481

100

0.379
  covR Streptococcus salivarius strain HSISS4

35.683

100

0.362

Multiple sequence alignment