Detailed information NTG0061614

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: EKM74_RS04200
• Genome accession: NZ_AP019306
• Coordinates: 744810..745523 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain TUM9463
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 739810..750523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EKM74_RS04140	-	741011..741274 (-)	264	WP_001205732.1	hypothetical protein	-
EKM74_RS04145	-	741283..741543 (-)	261	WP_000291510.1	DUF1108 family protein	-
EKM74_RS04150	-	741548..741850 (-)	303	WP_042109511.1	DUF2482 family protein	-
EKM74_RS04155	-	741945..742106 (-)	162	WP_000048129.1	DUF1270 family protein	-
EKM74_RS04160	-	742103..742426 (-)	324	WP_001120201.1	DUF771 domain-containing protein	-
EKM74_RS04165	-	742481..742861 (+)	381	WP_000762521.1	DUF2513 domain-containing protein	-
EKM74_RS04170	-	742848..743045 (-)	198	WP_001148856.1	hypothetical protein	-
EKM74_RS04175	-	743061..743813 (-)	753	WP_001148605.1	phage antirepressor KilAC domain-containing protein	-
EKM74_RS04180	-	743864..744193 (+)	330	WP_000128909.1	hypothetical protein	-
EKM74_RS04185	-	744182..744397 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
EKM74_RS04190	-	744413..744676 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
EKM74_RS04195	-	744673..744847 (-)	175	Protein_769	transcriptional regulator	-
EKM74_RS04200	irvR	744810..745523 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
EKM74_RS04205	-	745539..746471 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
EKM74_RS04210	-	746477..746818 (+)	342	WP_000591749.1	hypothetical protein	-
EKM74_RS04215	-	747022..747204 (+)	183	WP_000694772.1	hypothetical protein	-
EKM74_RS04220	-	747304..748287 (+)	984	WP_001558608.1	glycosyltransferase family 2 protein	-
EKM74_RS04225	-	748298..748540 (+)	243	WP_000427213.1	hypothetical protein	-
EKM74_RS04230	-	748603..749640 (+)	1038	WP_000857180.1	tyrosine-type recombinase/integrase	-
EKM74_RS04235	sph	749697..750521 (+)	825	Protein_777	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=61614 EKM74_RS04200 WP_001031454.1 744810..745523(+) (irvR) [Staphylococcus aureus strain TUM9463]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=61614 EKM74_RS04200 WP_001031454.1 744810..745523(+) (irvR) [Staphylococcus aureus strain TUM9463]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTATGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401