Detailed information NTG0061611

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SCI_RS08175
• Genome accession: NC_022238
• Coordinates: 1642529..1643596 (-)
• Length: 355 a.a.
• NCBI ID: WP_006268109.1
• Uniprot ID: F9P7H5
• Organism: Streptococcus constellatus subsp. pharyngis C1050
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1637529..1648596

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCI_RS08155 (SCI_1599)	-	1638160..1639614 (+)	1455	WP_020998023.1	sucrose-6-phosphate hydrolase	-
SCI_RS08160 (SCI_1600)	-	1639595..1640560 (+)	966	WP_006268416.1	LacI family DNA-binding transcriptional regulator	-
SCI_RS08165 (SCI_1601)	-	1640630..1641452 (-)	823	Protein_1614	Cof-type HAD-IIB family hydrolase	-
SCI_RS08170 (SCI_1602)	amiF	1641595..1642518 (-)	924	WP_020998024.1	ATP-binding cassette domain-containing protein	Regulator
SCI_RS08175 (SCI_1603)	amiE	1642529..1643596 (-)	1068	WP_006268109.1	ABC transporter ATP-binding protein	Regulator
SCI_RS08180 (SCI_1604)	amiD	1643605..1644531 (-)	927	WP_006268005.1	oligopeptide ABC transporter permease OppC	Regulator
SCI_RS08185 (SCI_1605)	amiC	1644531..1646027 (-)	1497	WP_006268182.1	ABC transporter permease	Regulator
SCI_RS08190 (SCI_1606)	amiA3	1646391..1648370 (-)	1980	WP_020998025.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39582.24 Da
• Isoelectric Point: 4.7899

>NTDB_id=61611 SCI_RS08175 WP_006268109.1 1642529..1643596(-) (amiE) [Streptococcus constellatus subsp. pharyngis C1050]
MTQEKNVILTARDIVVEFDVRDKVLTAIRGVSLDLIEGEVLALVGESGSGKSVLTKTFTGMLEDNGRVAQGSINYRGQDL
TKLKSNKDWEPIRGVKIATIFQDPMTSLDPINTIGSQITEVIVKHQKKTAKEAKEMAIDYMNKVGIPDAEKRFSEYPFQY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIIDLLKSLQQEYQFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEDVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYSHLQGDAFALRSDYAMEIDFEEKPPQIYVSDTHWAK
TWLLHENAPKVNKPAVIDDLHEKISSKMGFAHLDA

Nucleotide

• Length: 1068 bp

>NTDB_id=61611 SCI_RS08175 WP_006268109.1 1642529..1643596(-) (amiE) [Streptococcus constellatus subsp. pharyngis C1050]
ATGACACAAGAAAAAAATGTAATATTGACTGCCCGCGATATTGTCGTGGAATTTGACGTTCGTGATAAAGTCTTAACCGC
CATTCGTGGTGTATCACTTGACCTCATCGAAGGTGAAGTTCTTGCTCTCGTAGGAGAGTCAGGTTCTGGTAAATCTGTTT
TAACAAAGACTTTTACTGGAATGTTAGAGGATAATGGTCGAGTAGCGCAAGGATCGATTAACTATCGTGGACAAGATTTG
ACAAAATTGAAATCCAATAAAGATTGGGAACCTATTCGTGGTGTTAAAATTGCGACTATTTTCCAAGACCCAATGACAAG
TTTAGACCCAATTAACACGATTGGTAGCCAGATTACAGAAGTTATTGTAAAACATCAAAAGAAAACGGCAAAAGAAGCGA
AGGAAATGGCTATTGACTATATGAATAAAGTCGGTATTCCTGATGCTGAAAAGCGTTTTAGTGAGTATCCTTTCCAATAT
TCAGGAGGAATGCGTCAACGGATCGTTATTGCCATTGCGCTTGCTTGTCGTCCTGATATCCTAATCTGTGATGAACCTAC
AACAGCGCTTGATGTTACCATTCAAGCACAAATCATTGATTTGTTGAAATCATTGCAACAAGAGTATCAATTCACTACTA
TTTTTATCACCCACGACCTTGGAGTGGTAGCAAGTATTGCGGATAAAGTTGCCGTTATGTATGCTGGAGAAATCGTCGAG
TATGGTACAGTAGAAGACGTCTTTTATGATCCACGTCATCCTTATACTTGGAGCTTGTTATCAAGCTTGCCACAGTTGGC
AGATGATAAAGGAGAGCTTTACTCTATTCCTGGCACACCGCCGTCTCTTTATTCACACTTGCAAGGAGATGCTTTCGCTC
TTCGTTCAGATTATGCGATGGAAATTGATTTTGAGGAAAAACCACCTCAAATCTATGTATCAGATACACATTGGGCAAAA
ACGTGGTTGCTTCATGAAAATGCTCCAAAAGTGAATAAACCTGCTGTTATTGATGATTTACATGAAAAAATTAGCTCAAA
AATGGGTTTTGCTCATTTAGACGCTTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: F9P7H5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	86.402	99.437	0.859
amiE	Streptococcus thermophilus LMG 18311	84.986	99.437	0.845
amiE	Streptococcus thermophilus LMD-9	84.986	99.437	0.845
oppD	Streptococcus mutans UA159	55.65	99.718	0.555