Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SII_RS05960 Genome accession   NC_022237
Coordinates   1228703..1230853 (-) Length   716 a.a.
NCBI ID   WP_020998898.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1223703..1235853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS05935 (SII_1171) - 1224048..1224737 (+) 690 WP_020998895.1 CPBP family intramembrane glutamic endopeptidase -
  SII_RS05940 (SII_1172) comE/blpR 1224937..1225683 (+) 747 WP_037582857.1 response regulator transcription factor Regulator
  SII_RS05945 (SII_1173) - 1225685..1227001 (+) 1317 WP_020998896.1 sensor histidine kinase -
  SII_RS05950 (SII_1174) - 1227082..1227234 (-) 153 WP_003073362.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SII_RS05955 (SII_1175) - 1227331..1228692 (-) 1362 WP_020998897.1 bacteriocin secretion accessory protein -
  SII_RS05960 (SII_1176) comA/nlmT 1228703..1230853 (-) 2151 WP_020998898.1 peptide cleavage/export ABC transporter Regulator
  SII_RS05965 (SII_1177) - 1231334..1231708 (+) 375 WP_041823246.1 hypothetical protein -
  SII_RS05970 (SII_1178) - 1231781..1232386 (-) 606 WP_003073371.1 superoxide dismutase -
  SII_RS05975 (SII_1179) holA 1232457..1233494 (-) 1038 WP_020998900.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80503.04 Da        Isoelectric Point: 9.1639

>NTDB_id=61530 SII_RS05960 WP_020998898.1 1228703..1230853(-) (comA/nlmT) [Streptococcus intermedius C270]
MNVKKTFVPQIDARDCGVAALASVAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMRSTLGMVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSILIIVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNYDVMQSNSMVNSAIIEDINGIETIKSLTSEEARYQKIDSEFVNYLDKSFTLSKYSIFQTTLKQGFQLI
LNVLILWLGAHLVISEKISIGQLITFTALLSYFTNSLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQTLTEKGFLA
GDITFHNVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFNGSILENLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGFHAELMERQGFYHHLFNK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=61530 SII_RS05960 WP_020998898.1 1228703..1230853(-) (comA/nlmT) [Streptococcus intermedius C270]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCGTTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGATCCAAGTGTAAAAATAACCAAGATATCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTTTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGACGAATACATTCCAAATCAAATGAGATCAACTCTTGGAATGGTGTCTATTGGTCTGATTATTA
CTTATATTTTGCAGCAAATGATGAGTTTTTCCAGAGATTATTTATTGATTGTACTTAGTCAGCGGCTGACCATCGATGTG
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTCTATTTTGATAA
TAGTAGGAGGGGTATTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCCATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATTATGACGTCATGCAAAGCAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAGCTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGACAAATCTTTTACGCTTAGTAAATATTCTATTTTTCAAACAACTCTTAAACAAGGCTTTCAATTGATT
TTAAATGTGCTTATTTTATGGCTCGGTGCGCATTTAGTTATATCTGAGAAAATCTCAATTGGGCAGCTCATCACATTTAC
GGCTCTACTTTCTTATTTTACAAATTCTCTTGAAAGTATTATTAATCTGCAAACTAAGCTGCAATCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATTTAGTAGAGTCTGAATTTAAAACTAAGCAAACACTTACAGAGAAAGGTTTCTTGGCT
GGTGATATTACGTTCCATAATGTCTCCTATAAATATGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGACCTTAAAATGATTGATAAGAAGACGCTTCGTCAGTATATCAAT
TATTTACCACAACAAGCCTATATTTTTAATGGTTCCATCTTAGAAAATCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGACGAAGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAGGTTATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATTCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-648)

ABC transporter transmembrane region (ABC_membrane)

(168-437)

Peptidase C39 family (Peptidase_C39)

(6-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.214

99.022

0.715
  comA Streptococcus mitis NCTC 12261

67.041

99.581

0.668
  comA Streptococcus mitis SK321

66.9

99.581

0.666
  comA Streptococcus pneumoniae D39

66.339

99.581

0.661
  comA Streptococcus pneumoniae Rx1

66.339

99.581

0.661
  comA Streptococcus pneumoniae R6

66.339

99.581

0.661
  comA Streptococcus gordonii str. Challis substr. CH1

66.199

99.581

0.659
  comA Streptococcus pneumoniae TIGR4

65.919

99.581

0.656

Multiple sequence alignment