Detailed information NTG0061529

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: SII_RS05940
• Genome accession: NC_022237
• Coordinates: 1224937..1225683 (+)
• Length: 248 a.a.
• NCBI ID: WP_037582857.1
• Uniprot ID: -
• Organism: Streptococcus intermedius C270
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1219937..1230683

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SII_RS05895 (SII_1163)	-	1220342..1220560 (-)	219	WP_020998889.1	Blp family class II bacteriocin	-
SII_RS05900 (SII_1164)	-	1220790..1221110 (-)	321	WP_020998890.1	hypothetical protein	-
SII_RS05905	-	1221146..1221373 (-)	228	WP_041823245.1	hypothetical protein	-
SII_RS05910 (SII_1165)	-	1221467..1221760 (-)	294	WP_020998891.1	bacteriocin immunity protein	-
SII_RS05915 (SII_1166)	-	1221989..1222204 (-)	216	WP_041823339.1	bacteriocin class II family protein	-
SII_RS09765 (SII_1167)	-	1222415..1222666 (-)	252	WP_020998893.1	hypothetical protein	-
SII_RS05920 (SII_1168)	-	1222981..1223202 (-)	222	WP_003025422.1	Blp family class II bacteriocin	-
SII_RS05925 (SII_1169)	-	1223210..1223530 (-)	321	WP_003037422.1	hypothetical protein	-
SII_RS05930 (SII_1170)	-	1223618..1223842 (-)	225	WP_003025424.1	Blp family class II bacteriocin	-
SII_RS05935 (SII_1171)	-	1224048..1224737 (+)	690	WP_020998895.1	CPBP family intramembrane glutamic endopeptidase	-
SII_RS05940 (SII_1172)	comE/blpR	1224937..1225683 (+)	747	WP_037582857.1	response regulator transcription factor	Regulator
SII_RS05945 (SII_1173)	-	1225685..1227001 (+)	1317	WP_020998896.1	sensor histidine kinase	-
SII_RS05950 (SII_1174)	-	1227082..1227234 (-)	153	WP_003073362.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SII_RS05955 (SII_1175)	-	1227331..1228692 (-)	1362	WP_020998897.1	bacteriocin secretion accessory protein	-

Sequence

Protein

• Length: 248 a.a.
• Molecular weight: 28725.13 Da
• Isoelectric Point: 7.6681

>NTDB_id=61529 SII_RS05940 WP_037582857.1 1224937..1225683(+) (comE/blpR) [Streptococcus intermedius C270]
MNIFILEDDLTQQYYMETIVEEIIEKHRLQYHHFEVFGKPKQLLEAISEKGSHQVFFLDIEIKTEEKKGLDVAKKIREID
PYAIIVFVTSHSELMPAAFKLQVGALDYLDKSLSKEALKKRIETALLHTENLTGKGLADDSLLFETPHTQIQVPFKDILY
IETSSRPHRLVLYTHRGRTEFTANLSDMLKKEKRFYQCHRSFVVNPANVHQVDKVNHILHFQNGATCLVSRSKIKGLTEA
IAALHRRE

Nucleotide

• Length: 747 bp

>NTDB_id=61529 SII_RS05940 WP_037582857.1 1224937..1225683(+) (comE/blpR) [Streptococcus intermedius C270]
ATGAATATTTTTATTTTAGAAGATGATCTTACTCAACAATATTATATGGAGACTATTGTTGAAGAAATTATCGAAAAACA
TCGTCTTCAATATCACCATTTTGAAGTTTTTGGAAAACCTAAACAATTACTAGAAGCCATATCTGAGAAAGGAAGCCATC
AGGTTTTCTTTTTGGATATTGAAATCAAAACTGAAGAAAAAAAGGGCTTAGACGTCGCCAAAAAGATACGCGAGATAGAT
CCTTATGCCATTATTGTCTTTGTAACCAGTCACTCTGAATTGATGCCGGCAGCGTTTAAACTGCAAGTCGGCGCCCTTGA
CTATCTTGACAAATCGTTATCAAAAGAAGCTTTGAAAAAACGGATCGAAACTGCGCTGCTACATACTGAAAACCTAACAG
GCAAAGGCCTGGCAGACGATTCTCTTCTCTTTGAAACACCTCATACACAAATACAAGTGCCGTTTAAAGATATTCTTTAC
ATTGAAACTTCCTCTCGTCCTCACCGTTTAGTACTTTACACACATAGAGGGCGTACGGAATTTACTGCCAATCTTTCAGA
TATGTTAAAAAAAGAAAAACGGTTCTACCAATGTCATCGTTCCTTTGTTGTTAACCCAGCTAATGTTCATCAAGTGGATA
AAGTAAATCATATCCTTCACTTCCAGAATGGTGCTACTTGTCTTGTTTCTAGATCAAAAATAAAAGGGTTAACAGAAGCT
ATTGCAGCCCTGCACCGGAGGGAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-123)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	49.798	99.597	0.496
comE/comE1	Streptococcus equinus JB1	45.992	95.565	0.44