Detailed information NTG0061529

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: EKM72_RS04215
• Genome accession: NZ_AP019305
• Coordinates: 747202..747915 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain TUM9458
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 742202..752915

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EKM72_RS04155	-	743403..743666 (-)	264	WP_001205732.1	hypothetical protein	-
EKM72_RS04160	-	743675..743935 (-)	261	WP_000291510.1	DUF1108 family protein	-
EKM72_RS04165	-	743940..744242 (-)	303	WP_042109511.1	DUF2482 family protein	-
EKM72_RS04170	-	744337..744498 (-)	162	WP_000048129.1	DUF1270 family protein	-
EKM72_RS04175	-	744495..744818 (-)	324	WP_001120201.1	DUF771 domain-containing protein	-
EKM72_RS04180	-	744873..745253 (+)	381	WP_000762521.1	DUF2513 domain-containing protein	-
EKM72_RS04185	-	745240..745437 (-)	198	WP_001148856.1	hypothetical protein	-
EKM72_RS04190	-	745453..746205 (-)	753	WP_001148605.1	phage antirepressor KilAC domain-containing protein	-
EKM72_RS04195	-	746256..746585 (+)	330	WP_000128909.1	hypothetical protein	-
EKM72_RS04200	-	746574..746789 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
EKM72_RS04205	-	746805..747068 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
EKM72_RS04210	-	747065..747239 (-)	175	Protein_772	transcriptional regulator	-
EKM72_RS04215	irvR	747202..747915 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
EKM72_RS04220	-	747931..748863 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
EKM72_RS04225	-	748869..749210 (+)	342	WP_000591749.1	hypothetical protein	-
EKM72_RS04230	-	749414..749596 (+)	183	WP_000694772.1	hypothetical protein	-
EKM72_RS04235	-	749696..750679 (+)	984	WP_001558608.1	glycosyltransferase family 2 protein	-
EKM72_RS04240	-	750690..750932 (+)	243	WP_000427213.1	hypothetical protein	-
EKM72_RS04245	-	750995..752032 (+)	1038	WP_000857180.1	tyrosine-type recombinase/integrase	-
EKM72_RS04250	sph	752089..752913 (+)	825	Protein_780	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=61529 EKM72_RS04215 WP_001031454.1 747202..747915(+) (irvR) [Staphylococcus aureus strain TUM9458]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=61529 EKM72_RS04215 WP_001031454.1 747202..747915(+) (irvR) [Staphylococcus aureus strain TUM9458]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTATGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401