Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LIO32_RS05890 Genome accession   NZ_CP085087
Coordinates   1176723..1177394 (-) Length   223 a.a.
NCBI ID   WP_024394126.1    Uniprot ID   -
Organism   Streptococcus suis strain Ssuis_MA2     
Function   repress competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1178353..1179555 1176723..1177394 flank 959


Gene organization within MGE regions


Location: 1176723..1179555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO32_RS05890 ciaR 1176723..1177394 (-) 672 WP_024394126.1 response regulator transcription factor Regulator
  LIO32_RS05895 - 1177588..1177968 (-) 381 WP_023369940.1 hypothetical protein -
  LIO32_RS05900 - 1178353..1179555 (+) 1203 WP_319022741.1 IS110 family transposase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25306.00 Da        Isoelectric Point: 4.2183

>NTDB_id=615273 LIO32_RS05890 WP_024394126.1 1176723..1177394(-) (ciaR) [Streptococcus suis strain Ssuis_MA2]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=615273 LIO32_RS05890 WP_024394126.1 1176723..1177394(-) (ciaR) [Streptococcus suis strain Ssuis_MA2]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGATCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGACCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.583

100

0.906
  ciaR Streptococcus pneumoniae Rx1

88.789

100

0.888
  ciaR Streptococcus pneumoniae D39

88.789

100

0.888
  ciaR Streptococcus pneumoniae R6

88.789

100

0.888
  ciaR Streptococcus pneumoniae TIGR4

88.789

100

0.888
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.053

100

0.386
  vicR Streptococcus mutans UA159

35.897

100

0.377
  micA Streptococcus pneumoniae Cp1015

34.764

100

0.363