Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SCRE_RS08580 Genome accession   NC_022236
Coordinates   1731159..1731452 (-) Length   97 a.a.
NCBI ID   WP_003035318.1    Uniprot ID   I0SGQ0
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1726159..1736452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS08560 (SCRE_1681) - 1728147..1729346 (-) 1200 WP_006267970.1 acetate kinase -
  SCRE_RS08565 (SCRE_1682) comYH 1729393..1730346 (-) 954 WP_020998065.1 class I SAM-dependent methyltransferase Machinery gene
  SCRE_RS08570 (SCRE_1683) comGG 1730431..1730757 (-) 327 WP_020998066.1 competence type IV pilus minor pilin ComGG -
  SCRE_RS08575 (SCRE_1684) comGF/cglF 1730738..1731175 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  SCRE_RS08580 (SCRE_1685) comGE/cglE 1731159..1731452 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  SCRE_RS08585 (SCRE_1686) comYD 1731424..1731852 (-) 429 WP_020998067.1 competence type IV pilus minor pilin ComGD Machinery gene
  SCRE_RS08590 (SCRE_1687) comYC 1731812..1732129 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  SCRE_RS08595 (SCRE_1688) comYB 1732126..1733148 (-) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  SCRE_RS08600 (SCRE_1689) comYA 1733090..1734031 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  SCRE_RS08605 - 1734101..1734466 (-) 366 WP_022525692.1 DUF1033 family protein -
  SCRE_RS08610 (SCRE_1690) glnA 1734654..1736000 (-) 1347 WP_020998070.1 type I glutamate--ammonia ligase -
  SCRE_RS08615 (SCRE_1691) - 1736039..1736398 (-) 360 WP_003073972.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10936.85 Da        Isoelectric Point: 10.4707

>NTDB_id=61491 SCRE_RS08580 WP_003035318.1 1731159..1731452(-) (comGE/cglE) [Streptococcus constellatus subsp. pharyngis C232]
MENLRKQYVRGTILLEALLASAVFAFIVTLLLGQIHQSRQTENDLLKKEEVLRVANMALQTKQSHLTINGIEVRVKKSQQ
GIQIYHGKELIVGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=61491 SCRE_RS08580 WP_003035318.1 1731159..1731452(-) (comGE/cglE) [Streptococcus constellatus subsp. pharyngis C232]
ATGGAAAATTTAAGAAAACAATACGTTAGAGGAACGATTTTATTAGAAGCTTTATTGGCATCGGCTGTTTTTGCGTTTAT
TGTGACCTTGTTATTGGGGCAGATCCATCAGTCTCGACAGACAGAAAATGATTTACTGAAAAAAGAAGAAGTTCTAAGAG
TGGCTAATATGGCATTACAAACAAAGCAAAGCCATTTAACAATAAACGGTATTGAAGTTCGTGTTAAAAAAAGTCAACAA
GGCATCCAGATTTATCATGGGAAGGAGCTGATTGTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SGQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

42.424

100

0.433
  comYE Streptococcus mutans UA159

42.424

100

0.433

Multiple sequence alignment