Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   SCRE_RS08575 Genome accession   NC_022236
Coordinates   1730738..1731175 (-) Length   145 a.a.
NCBI ID   WP_003035329.1    Uniprot ID   F9P803
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1725738..1736175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS08555 (SCRE_1680) glmS 1725942..1727756 (-) 1815 WP_020998064.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
  SCRE_RS08560 (SCRE_1681) - 1728147..1729346 (-) 1200 WP_006267970.1 acetate kinase -
  SCRE_RS08565 (SCRE_1682) comYH 1729393..1730346 (-) 954 WP_020998065.1 class I SAM-dependent methyltransferase Machinery gene
  SCRE_RS08570 (SCRE_1683) comGG 1730431..1730757 (-) 327 WP_020998066.1 competence type IV pilus minor pilin ComGG -
  SCRE_RS08575 (SCRE_1684) comGF/cglF 1730738..1731175 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  SCRE_RS08580 (SCRE_1685) comGE/cglE 1731159..1731452 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  SCRE_RS08585 (SCRE_1686) comYD 1731424..1731852 (-) 429 WP_020998067.1 competence type IV pilus minor pilin ComGD Machinery gene
  SCRE_RS08590 (SCRE_1687) comYC 1731812..1732129 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  SCRE_RS08595 (SCRE_1688) comYB 1732126..1733148 (-) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  SCRE_RS08600 (SCRE_1689) comYA 1733090..1734031 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  SCRE_RS08605 - 1734101..1734466 (-) 366 WP_022525692.1 DUF1033 family protein -
  SCRE_RS08610 (SCRE_1690) glnA 1734654..1736000 (-) 1347 WP_020998070.1 type I glutamate--ammonia ligase -

Sequence

Protein


Download         Length: 145 a.a.        Molecular weight: 16865.57 Da        Isoelectric Point: 10.6422

>NTDB_id=61490 SCRE_RS08575 WP_003035329.1 1730738..1731175(-) (comGF/cglF) [Streptococcus constellatus subsp. pharyngis C232]
MFKANKVKAFTLLEALVALFVISGSVLLFQSMTRLLASEVRARQHSEQREWLLFAHQLEAELIRSSFEKVENNRLYMKQD
GKTIAFGKSSGQDFRKTNANGKGYQPMIYNVKKAEISQKNELIHIRMTFKRGLEREFVYRVETKS

Nucleotide


Download         Length: 438 bp        

>NTDB_id=61490 SCRE_RS08575 WP_003035329.1 1730738..1731175(-) (comGF/cglF) [Streptococcus constellatus subsp. pharyngis C232]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACACTTTTAGAGGCTCTGGTTGCCCTCTTTGTAATCAGCGGGAGTGTGCT
ATTATTTCAATCGATGACGCGTCTTCTGGCTTCGGAGGTCCGAGCTCGACAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCCCATCAATTAGAAGCGGAATTGATTCGTTCTTCATTTGAAAAAGTGGAGAATAATCGTTTATACATGAAGCAGGAC
GGTAAGACGATTGCATTTGGAAAGTCAAGTGGACAAGATTTCAGAAAAACCAATGCAAATGGGAAAGGCTATCAGCCTAT
GATTTATAATGTGAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATATCAGAATGACATTTAAGCGAGGATTGG
AAAGGGAGTTCGTCTATCGTGTGGAAACAAAGAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(39-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P803

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae R6

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae TIGR4

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae Rx1

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae D39

66.429

96.552

0.641
  comGF/cglF Streptococcus mitis NCTC 12261

65.714

96.552

0.634
  comGF/cglF Streptococcus mitis SK321

65.714

96.552

0.634
  comYF Streptococcus mutans UA159

43.972

97.241

0.428
  comYF Streptococcus mutans UA140

43.972

97.241

0.428
  comGF Lactococcus lactis subsp. cremoris KW2

42.963

93.103

0.4

Multiple sequence alignment