Detailed information NTG0613698

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: NPS17_RS01430
• Genome accession: NZ_CP101985
• Coordinates: 306410..307306 (+)
• Length: 298 a.a.
• NCBI ID: WP_002272265.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain COCC33-14R
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 301410..312306

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS17_RS01400 (NPS17_01400)	-	302263..302826 (+)	564	WP_258969046.1	nucleotidyltransferase family protein	-
NPS17_RS01405 (NPS17_01405)	-	303253..304266 (+)	1014	WP_002288918.1	YdcF family protein	-
NPS17_RS01410 (NPS17_01410)	-	304343..305119 (+)	777	WP_002293236.1	MBL fold metallo-hydrolase	-
NPS17_RS01415 (NPS17_01415)	tadA	305119..305589 (+)	471	WP_002293239.1	tRNA adenosine(34) deaminase TadA	-
NPS17_RS01420 (NPS17_01420)	-	305586..306149 (+)	564	WP_002262912.1	hypothetical protein	-
NPS17_RS01430 (NPS17_01430)	comR	306410..307306 (+)	897	WP_002272265.1	XRE family transcriptional regulator	Regulator
NPS17_RS01435 (NPS17_01435)	-	308076..308825 (+)	750	WP_002276184.1	hypothetical protein	-
NPS17_RS01440 (NPS17_01440)	-	308836..309414 (+)	579	WP_002302153.1	CPBP family intramembrane glutamic endopeptidase	-
NPS17_RS01445 (NPS17_01445)	-	309424..309852 (+)	429	WP_002302151.1	Msa family membrane protein	-
NPS17_RS01450 (NPS17_01450)	-	309845..310711 (+)	867	WP_002272214.1	ABC transporter ATP-binding protein	-
NPS17_RS01455 (NPS17_01455)	-	310714..311463 (+)	750	WP_002272215.1	hypothetical protein	-

Sequence

Protein

• Length: 298 a.a.
• Molecular weight: 34855.76 Da
• Isoelectric Point: 4.3876

>NTDB_id=613698 NPS17_RS01430 WP_002272265.1 306410..307306(+) (comR) [Streptococcus mutans strain COCC33-14R]
MSVKETIGQKIREEREKKGLSREQLCDTEEELTARQLVRIELGQSLPSIVKLEFIAKKLETDLTTLLAGESITIPEEYFT
MKYQLFKFPTYGDPKRLEQKTQMIEDIYEKYFNVLPEEELFTLELLDNSLDYISTKEAEAAEIIFEDFFKQLLLKEKYMF
NDLLLVSYYAIQYQDKNYNEKTLKILEETILKQEVSGDEYYNIELLGALTAIAGVYLDHAEYSKLKSLVDRMHEVITETQ
QYSAKPIVLIYEAKYYLYSEQNKEKAKGCYDLAALLAQNFGDDVLETNIEAERKKDQV

Nucleotide

• Length: 897 bp

>NTDB_id=613698 NPS17_RS01430 WP_002272265.1 306410..307306(+) (comR) [Streptococcus mutans strain COCC33-14R]
ATGAGTGTAAAGGAAACGATTGGTCAGAAAATTAGGGAAGAAAGAGAAAAAAAGGGTCTGTCACGTGAACAACTATGTGA
TACTGAAGAAGAATTAACGGCTCGTCAACTGGTACGTATTGAACTGGGGCAATCTTTACCGTCTATTGTAAAGCTGGAGT
TTATTGCAAAAAAATTGGAGACTGATTTAACCACTTTACTTGCAGGTGAAAGTATTACCATTCCAGAAGAATATTTCACT
ATGAAGTATCAGCTTTTCAAATTTCCCACTTATGGGGATCCTAAGCGTCTGGAACAGAAAACGCAAATGATTGAAGATAT
TTATGAAAAGTATTTTAATGTTTTGCCGGAGGAGGAGCTTTTTACTTTGGAATTGCTGGATAATTCTTTAGATTATATCT
CTACAAAAGAAGCAGAGGCAGCTGAAATCATCTTTGAAGACTTTTTTAAACAGTTGCTGCTAAAAGAAAAGTATATGTTC
AATGATTTGCTACTGGTATCGTACTATGCTATTCAATATCAAGATAAAAATTATAATGAAAAAACATTAAAGATATTAGA
AGAAACTATTCTGAAGCAAGAGGTTTCAGGTGATGAATACTATAATATTGAACTTTTAGGAGCATTGACAGCTATAGCAG
GCGTTTATCTAGATCATGCTGAGTATTCTAAATTAAAAAGTTTAGTAGATAGAATGCATGAAGTGATTACAGAGACACAG
CAGTACAGTGCTAAGCCTATAGTATTAATTTATGAGGCTAAATACTATCTCTATAGTGAACAAAACAAGGAGAAAGCAAA
AGGATGCTATGATTTAGCTGCTTTGCTGGCTCAGAATTTTGGTGATGATGTCTTAGAGACAAACATTGAAGCTGAAAGAA
AAAAAGATCAGGTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix domain (HTH_19) (8-70)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	44.108	99.664	0.44
comR	Streptococcus thermophilus LMD-9	44.108	99.664	0.44
comR	Streptococcus salivarius strain HSISS4	44.108	99.664	0.44
comR	Streptococcus salivarius SK126	44.108	99.664	0.44
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.472	100	0.416
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	40.803	100	0.409