Detailed information NTG0061230

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAAG_RS09515
• Genome accession: NC_022113
• Coordinates: 1919867..1920910 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus subsp. aureus 55/2053
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1914867..1925910

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAAG_RS09485 (SAAG_02398)	-	1915288..1916544 (-)	1257	WP_001793983.1	aminopeptidase	-
SAAG_RS09490 (SAAG_02399)	-	1916547..1916747 (-)	201	WP_000180460.1	DUF1128 family protein	-
SAAG_RS09495 (SAAG_02400)	-	1916894..1917358 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
SAAG_RS09500 (SAAG_02401)	-	1917365..1917640 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAAG_RS09505 (SAAG_02402)	-	1917918..1919135 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
SAAG_RS09510 (SAAG_02403)	vraR	1919248..1919877 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SAAG_RS09515 (SAAG_02404)	vraS	1919867..1920910 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SAAG_RS09520 (SAAG_02405)	liaF	1920907..1921608 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SAAG_RS09525 (SAAG_02406)	-	1921623..1922009 (-)	387	WP_001110177.1	hypothetical protein	-
SAAG_RS09530 (SAAG_02407)	map	1922226..1922984 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAAG_RS09535 (SAAG_02408)	-	1923569..1924555 (+)	987	WP_001014423.1	FUSC family protein	-
SAAG_RS09540 (SAAG_02409)	-	1924744..1925157 (-)	414	WP_001643743.1	hypothetical protein	-
SAAG_RS09545	-	1925186..1925296 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=61230 SAAG_RS09515 WP_001017131.1 1919867..1920910(-) (vraS) [Staphylococcus aureus subsp. aureus 55/2053]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=61230 SAAG_RS09515 WP_001017131.1 1919867..1920910(-) (vraS) [Staphylococcus aureus subsp. aureus 55/2053]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1