Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LA387_RS08835 Genome accession   NZ_CP084377
Coordinates   1726251..1727468 (-) Length   405 a.a.
NCBI ID   WP_003133516.1    Uniprot ID   A0A3D4RHV6
Organism   Lactococcus garvieae strain Lg-Granada     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1721251..1732468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA387_RS08810 - 1721549..1722298 (+) 750 WP_003133521.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  LA387_RS08815 - 1722458..1723507 (+) 1050 WP_003133520.1 BMP family lipoprotein -
  LA387_RS08820 - 1723533..1723757 (-) 225 WP_003133519.1 DUF1797 family protein -
  LA387_RS08825 - 1723808..1725142 (-) 1335 WP_003133518.1 glycosyltransferase family 4 protein -
  LA387_RS08830 - 1725155..1726153 (-) 999 WP_003133517.1 glycosyltransferase family 4 protein -
  LA387_RS08835 htrA 1726251..1727468 (-) 1218 WP_003133516.1 S1C family serine protease Regulator
  LA387_RS08840 rlmH 1727772..1728251 (+) 480 WP_003133515.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LA387_RS08845 - 1728248..1728895 (+) 648 WP_003133514.1 DNA alkylation repair protein -
  LA387_RS08850 yajC 1728970..1729305 (+) 336 WP_003133513.1 preprotein translocase subunit YajC -
  LA387_RS08855 - 1729506..1730243 (+) 738 WP_003133511.1 isoprenyl transferase -
  LA387_RS08860 - 1730240..1731034 (+) 795 WP_003133509.1 phosphatidate cytidylyltransferase -
  LA387_RS08865 eeP 1731210..1732457 (+) 1248 WP_003133508.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41787.63 Da        Isoelectric Point: 4.8808

>NTDB_id=610870 LA387_RS08835 WP_003133516.1 1726251..1727468(-) (htrA) [Lactococcus garvieae strain Lg-Granada]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNDSNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSGSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=610870 LA387_RS08835 WP_003133516.1 1726251..1727468(-) (htrA) [Lactococcus garvieae strain Lg-Granada]
ATGGCAAAGAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGAGGTAGTGCTATCTA
CCAAAACATGACCAATACACCATCATCTAATAACACTTCGGACAATTCTGTAAGTACGGTTAACGTCCAAGTCAATACAG
ATACAACCAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTCGGTGGAGGCGATACAAGCAGCAATGACAGTAACACGCCACAGCTGGCTGGTGAAGGTTCTGGTGT
TATTTATAAAAAGGATGGCAATACAGCATACATCGTTACCAACTATCACGTGATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCTGGCGGCCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGTAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTTGGTTC
TCCTCTTGGAAGTGAGTATGCCAACTCAGCAACGGAAGGGATTGTTTCAAGTCTTAATCGTAATGTTACGCTGCAAAACA
GCCAAGGCCAAACAATTAATGTGAACGCAATTCAAACCGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCACTCATA
AATATTCAGGGACAAGTCATCGGGATTACTTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCGGCAGTGGTGTCTC
TGTAGAAGGAATGGGCTTTGCGATTCCAGCCAATGATGTGGTCAATATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCACAAAATATGTTGGCTTCACTTAATCTTCCTGAA
AATGTGACAAATGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGTGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTGAACCTTCAAAGTACACTTTATAAGTCATCGATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTGCGAATATCAAGTTGGATAAGACAAGTAGTGATATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

PDZ domain (PDZ_2)

(296-392)

Peptidase family M50 (Peptidase_M50)

(294-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3D4RHV6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

53.634

98.519

0.528
  htrA Streptococcus pneumoniae Rx1

53.383

98.519

0.526
  htrA Streptococcus pneumoniae D39

53.383

98.519

0.526
  htrA Streptococcus pneumoniae R6

53.383

98.519

0.526
  htrA Streptococcus pneumoniae TIGR4

53.383

98.519

0.526
  htrA Streptococcus mutans UA159

56.085

93.333

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

96.543

0.523