Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   KE3_RS08910 Genome accession   NC_021900
Coordinates   1770692..1771213 (-) Length   173 a.a.
NCBI ID   WP_228380494.1    Uniprot ID   -
Organism   Streptococcus lutetiensis 033     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1765692..1776213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS08880 (KE3_1831) - 1766004..1766942 (-) 939 WP_020917484.1 3'-5' exoribonuclease YhaM family protein -
  KE3_RS08885 (KE3_1832) rmuC 1766932..1768206 (-) 1275 WP_020917485.1 DNA recombination protein RmuC -
  KE3_RS08890 (KE3_1833) - 1768208..1768840 (-) 633 WP_020917486.1 thiamine diphosphokinase -
  KE3_RS08895 (KE3_1834) rpe 1768833..1769495 (-) 663 WP_020917487.1 ribulose-phosphate 3-epimerase -
  KE3_RS08900 (KE3_1835) rsgA 1769502..1770374 (-) 873 WP_020917488.1 ribosome small subunit-dependent GTPase A -
  KE3_RS08910 comE/comE2 1770692..1771213 (-) 522 WP_228380494.1 LytR/AlgR family response regulator transcription factor Regulator
  KE3_RS11005 comE/comE2 1771198..1771425 (-) 228 WP_228380495.1 hypothetical protein Regulator
  KE3_RS08915 comD/comD2 1771983..1772816 (-) 834 WP_081665472.1 sensor histidine kinase Regulator
  KE3_RS08920 (KE3_1837) - 1773712..1774005 (-) 294 WP_020917489.1 bacteriocin immunity protein -
  KE3_RS08925 (KE3_1838) - 1774033..1774338 (-) 306 WP_020917490.1 bacteriocin immunity protein -
  KE3_RS08930 (KE3_1839) - 1774351..1774500 (-) 150 WP_020917491.1 hypothetical protein -
  KE3_RS08935 (KE3_1840) rsmA 1774907..1775779 (-) 873 WP_020917492.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -

Sequence

Protein


Download         Length: 173 a.a.        Molecular weight: 20445.84 Da        Isoelectric Point: 9.9341

>NTDB_id=60842 KE3_RS08910 WP_228380494.1 1770692..1771213(-) (comE/comE2) [Streptococcus lutetiensis 033]
MAKAIREKSRTATIVFVTTYSEFMLLTYRAQVSALNFIDKTDKDDAIKDNFKKCLQKVFEDQGFNIPKKIFVFENNKTKI
RIPLEDILYFETAESHRLKLITKTGQCHFYGSIKEVMQANQKLFRCHKSYLINLNNIVRLDKKEGLVYFDDDKACYVSRK
YIKDLRSKMENLK

Nucleotide


Download         Length: 522 bp        

>NTDB_id=60842 KE3_RS08910 WP_228380494.1 1770692..1771213(-) (comE/comE2) [Streptococcus lutetiensis 033]
GTGGCTAAGGCGATAAGGGAAAAATCACGAACAGCGACGATTGTTTTTGTGACGACTTACTCTGAATTCATGTTATTGAC
TTATCGAGCTCAAGTTAGTGCACTTAATTTTATTGATAAAACAGATAAAGATGATGCGATAAAAGATAATTTTAAAAAAT
GCTTGCAAAAGGTCTTTGAGGACCAAGGTTTTAACATTCCTAAGAAAATATTTGTTTTTGAAAATAACAAAACGAAAATC
CGCATTCCCTTGGAAGATATCCTTTATTTTGAAACTGCGGAAAGTCATCGCCTGAAGTTGATTACAAAAACTGGGCAATG
TCATTTTTATGGTTCAATCAAAGAAGTGATGCAAGCTAATCAGAAATTATTTAGATGTCATAAATCATATCTGATTAACC
TAAATAATATTGTTAGGTTAGATAAAAAAGAAGGTTTGGTTTATTTTGACGATGATAAAGCTTGTTATGTTTCTAGAAAA
TATATCAAAGACTTAAGGTCAAAAATGGAAAATCTGAAATAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(80-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

96.532

100

0.965
  comE/comE1 Streptococcus equinus JB1

45.294

98.266

0.445
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.5

100

0.382
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.5

100

0.382
  comE/blpR Streptococcus mutans UA159

39.053

97.688

0.382

Multiple sequence alignment