Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KE3_RS04955 Genome accession   NC_021900
Coordinates   977602..978444 (-) Length   280 a.a.
NCBI ID   WP_020916780.1    Uniprot ID   -
Organism   Streptococcus lutetiensis 033     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 965306..977465 977602..978444 flank 137


Gene organization within MGE regions


Location: 965306..978444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS04860 (KE3_1001) - 965306..966094 (-) 789 WP_020916763.1 DNA/RNA non-specific endonuclease -
  KE3_RS04865 (KE3_1002) - 966097..966441 (-) 345 WP_020916764.1 hypothetical protein -
  KE3_RS04870 (KE3_1003) - 966434..966772 (-) 339 WP_020916765.1 hypothetical protein -
  KE3_RS04875 (KE3_1004) - 967192..967476 (-) 285 WP_020916766.1 hypothetical protein -
  KE3_RS09995 (KE3_1005) - 967652..968488 (-) 837 WP_052317422.1 hypothetical protein -
  KE3_RS04885 (KE3_1006) - 968493..969506 (-) 1014 WP_020916768.1 hypothetical protein -
  KE3_RS04890 (KE3_1007) - 969584..970183 (+) 600 WP_020916769.1 hypothetical protein -
  KE3_RS04895 (KE3_1008) - 970180..970527 (-) 348 WP_020916770.1 hypothetical protein -
  KE3_RS04900 (KE3_1009) - 970608..970943 (-) 336 WP_020916771.1 hypothetical protein -
  KE3_RS04905 - 970946..971143 (-) 198 WP_043895039.1 hypothetical protein -
  KE3_RS04910 (KE3_1010) - 971136..971561 (-) 426 WP_020916772.1 thioredoxin family protein -
  KE3_RS04915 (KE3_1011) - 971554..971973 (-) 420 WP_020916773.1 hypothetical protein -
  KE3_RS10575 (KE3_1012) - 971987..972142 (-) 156 WP_014620303.1 hypothetical protein -
  KE3_RS04920 (KE3_1013) - 972154..972357 (-) 204 WP_020916774.1 hypothetical protein -
  KE3_RS10580 (KE3_1014) - 972354..972530 (-) 177 WP_020916775.1 hypothetical protein -
  KE3_RS04925 (KE3_1015) - 972679..974181 (-) 1503 WP_020916776.1 primase C-terminal domain-containing protein -
  KE3_RS04930 - 974178..974531 (-) 354 WP_187288143.1 hypothetical protein -
  KE3_RS04935 (KE3_1017) - 974743..975492 (-) 750 WP_014620308.1 hypothetical protein -
  KE3_RS04940 (KE3_1018) - 975516..976010 (-) 495 WP_020916778.1 hypothetical protein -
  KE3_RS04945 (KE3_1019) dcm 976024..977208 (-) 1185 WP_014620310.1 DNA (cytosine-5-)-methyltransferase -
  KE3_RS04950 (KE3_1020) - 977241..977453 (-) 213 WP_187288144.1 hypothetical protein -
  KE3_RS04955 (KE3_1021) dprA 977602..978444 (-) 843 WP_020916780.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31053.03 Da        Isoelectric Point: 9.1792

>NTDB_id=60825 KE3_RS04955 WP_020916780.1 977602..978444(-) (dprA) [Streptococcus lutetiensis 033]
MNNFELFKLKQAGLTNLNILAILEYQKQEKKSLSLRDMAVVSKCKNPILFMEKYKDLDSKTLRKVFNQYPSISILDDDYP
LELKHSYNPPVLLFYQGNIDLLNRPKIAVVGARTATQIGTKSVQKIIKELGNQFVIVSGLARGIDTSAHISALKNGGATI
AVIGCGLDVYYPKENKQLQEYLGKNHLILSEYTASEAPLKYHFPKRNRIIAGLSQGVIVAEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCITSGLDVLSEYQL

Nucleotide


Download         Length: 843 bp        

>NTDB_id=60825 KE3_RS04955 WP_020916780.1 977602..978444(-) (dprA) [Streptococcus lutetiensis 033]
ATGAATAACTTTGAACTATTTAAATTAAAACAAGCAGGACTAACAAATCTCAACATTCTAGCCATTTTAGAATATCAAAA
GCAAGAAAAGAAATCTCTTTCCTTGCGAGATATGGCAGTTGTGTCCAAATGTAAGAATCCTATTTTATTTATGGAAAAAT
ACAAAGATTTGGATAGTAAAACTTTGCGAAAAGTCTTTAATCAATACCCTAGTATTTCAATACTAGATGACGACTATCCG
CTGGAATTAAAACACTCTTATAATCCGCCTGTTTTGCTTTTTTATCAAGGCAATATTGATTTGCTCAATCGTCCGAAAAT
AGCAGTAGTAGGAGCACGCACAGCCACACAGATAGGAACCAAGTCCGTTCAAAAAATCATCAAAGAACTTGGAAATCAAT
TCGTCATTGTTAGTGGCTTAGCTAGGGGGATAGATACCAGTGCACATATTTCAGCACTAAAAAATGGCGGAGCGACAATA
GCAGTTATTGGTTGTGGTCTTGACGTCTATTATCCCAAAGAAAATAAGCAGTTGCAGGAGTATCTTGGAAAAAATCACTT
AATCTTGAGCGAATACACAGCATCAGAAGCGCCACTAAAATACCATTTTCCAAAACGCAATCGCATTATCGCAGGATTAT
CCCAAGGCGTCATAGTAGCAGAAGCTAAATTGCGATCTGGCAGCTTAATTACTTGTGAACGAGCCCTAGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGTAATATTTTAGACGGAAAATCTGACGGATGTCATCATTTAATCAAAGAAGGCGCAAAGTG
CATCACATCAGGATTAGATGTCCTTTCAGAGTACCAATTGTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

73.214

100

0.732
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis SK321

63.571

100

0.636
  dprA Lactococcus lactis subsp. cremoris KW2

60.432

99.286

0.6
  dprA Legionella pneumophila strain ERS1305867

41.909

86.071

0.361

Multiple sequence alignment