Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | LB317_RS05830 | Genome accession | NZ_CP083805 |
| Coordinates | 1241258..1242130 (+) | Length | 290 a.a. |
| NCBI ID | WP_031786943.1 | Uniprot ID | - |
| Organism | Staphylococcus argenteus strain 1801221 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1204662..1287031 | 1241258..1242130 | within | 0 |
Gene organization within MGE regions
Location: 1204662..1287031
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LB317_RS05665 (LB317_05675) | - | 1204817..1205020 (-) | 204 | WP_001198027.1 | TM2 domain-containing protein | - |
| LB317_RS05670 (LB317_05680) | - | 1205321..1205809 (+) | 489 | WP_031787794.1 | peptide deformylase | - |
| LB317_RS05675 (LB317_05685) | fmt | 1205802..1206737 (+) | 936 | WP_000161302.1 | methionyl-tRNA formyltransferase | - |
| LB317_RS05680 (LB317_05690) | rsmB | 1206734..1208041 (+) | 1308 | WP_031787795.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| LB317_RS05685 (LB317_05695) | rlmN | 1208044..1209138 (+) | 1095 | WP_000626892.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| LB317_RS05690 (LB317_05700) | - | 1209145..1209888 (+) | 744 | WP_000888496.1 | protein-serine/threonine phosphatase Stp1 | - |
| LB317_RS05695 (LB317_05705) | pknB | 1209885..1211879 (+) | 1995 | WP_031787796.1 | serine/threonine protein kinase Stk1 | - |
| LB317_RS05700 (LB317_05710) | rsgA | 1212146..1213021 (+) | 876 | WP_000847920.1 | ribosome small subunit-dependent GTPase A | - |
| LB317_RS05705 (LB317_05715) | rpe | 1213022..1213666 (+) | 645 | WP_031787797.1 | ribulose-phosphate 3-epimerase | - |
| LB317_RS05710 (LB317_05720) | - | 1213673..1214317 (+) | 645 | WP_031787798.1 | thiamine diphosphokinase | - |
| LB317_RS05715 (LB317_05725) | rpmB | 1214567..1214755 (-) | 189 | WP_000517908.1 | 50S ribosomal protein L28 | - |
| LB317_RS05720 (LB317_05730) | - | 1215199..1215573 (+) | 375 | WP_031787799.1 | Asp23/Gls24 family envelope stress response protein | - |
| LB317_RS05725 (LB317_05735) | fakA | 1215588..1217234 (+) | 1647 | WP_031787800.1 | fatty acid kinase catalytic subunit FakA | - |
| LB317_RS05730 (LB317_05740) | recG | 1217408..1219468 (+) | 2061 | WP_031787801.1 | ATP-dependent DNA helicase RecG | - |
| LB317_RS05735 (LB317_05745) | fapR | 1219873..1220445 (+) | 573 | WP_072292002.1 | transcription factor FapR | - |
| LB317_RS05740 (LB317_05750) | plsX | 1220450..1221436 (+) | 987 | WP_000239751.1 | phosphate acyltransferase PlsX | - |
| LB317_RS05745 (LB317_05755) | fabD | 1221429..1222355 (+) | 927 | WP_031787802.1 | ACP S-malonyltransferase | - |
| LB317_RS05750 (LB317_05760) | fabG | 1222348..1223082 (+) | 735 | WP_000167268.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| LB317_RS05755 (LB317_05765) | - | 1223552..1223785 (+) | 234 | WP_000426914.1 | acyl carrier protein | - |
| LB317_RS05760 (LB317_05770) | rnc | 1223901..1224632 (+) | 732 | WP_000043235.1 | ribonuclease III | - |
| LB317_RS05765 (LB317_05775) | smc | 1224764..1228333 (+) | 3570 | WP_031788253.1 | chromosome segregation protein SMC | - |
| LB317_RS05770 (LB317_05780) | ftsY | 1228330..1229580 (+) | 1251 | WP_031788254.1 | signal recognition particle-docking protein FtsY | - |
| LB317_RS05775 (LB317_05785) | - | 1229567..1229899 (+) | 333 | WP_000531321.1 | putative DNA-binding protein | - |
| LB317_RS05780 (LB317_05790) | ffh | 1229924..1231291 (+) | 1368 | WP_000863483.1 | signal recognition particle protein | - |
| LB317_RS05785 (LB317_05795) | rpsP | 1231620..1231895 (+) | 276 | WP_000268754.1 | 30S ribosomal protein S16 | - |
| LB317_RS05790 (LB317_05800) | rimM | 1232082..1232585 (+) | 504 | WP_001261978.1 | ribosome maturation factor RimM | - |
| LB317_RS05795 (LB317_05805) | trmD | 1232585..1233322 (+) | 738 | WP_031786939.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| LB317_RS05800 (LB317_05810) | rplS | 1233425..1233775 (+) | 351 | WP_000181404.1 | 50S ribosomal protein L19 | - |
| LB317_RS05805 (LB317_05815) | - | 1234017..1236623 (-) | 2607 | WP_031786940.1 | YfhO family protein | - |
| LB317_RS05810 (LB317_05820) | ylqF | 1237023..1237907 (+) | 885 | WP_031786941.1 | ribosome biogenesis GTPase YlqF | - |
| LB317_RS05815 (LB317_05825) | - | 1237891..1238658 (+) | 768 | WP_031786942.1 | ribonuclease HII | - |
| LB317_RS05820 (LB317_05830) | sucC | 1238767..1239933 (+) | 1167 | WP_001020805.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| LB317_RS05825 (LB317_05835) | sucD | 1239955..1240863 (+) | 909 | WP_000110253.1 | succinate--CoA ligase subunit alpha | - |
| LB317_RS05830 (LB317_05840) | dprA | 1241258..1242130 (+) | 873 | WP_031786943.1 | DNA-processing protein DprA | Machinery gene |
| LB317_RS05835 (LB317_05845) | topA | 1242304..1244379 (+) | 2076 | WP_072324151.1 | type I DNA topoisomerase | - |
| LB317_RS05840 (LB317_05850) | trmFO | 1244535..1245842 (+) | 1308 | WP_000195261.1 | FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO | - |
| LB317_RS05845 (LB317_05855) | xerC | 1246257..1247153 (+) | 897 | WP_031786945.1 | tyrosine recombinase XerC | - |
| LB317_RS05850 (LB317_05860) | hslV | 1247150..1247695 (+) | 546 | WP_000072683.1 | ATP-dependent protease subunit HslV | - |
| LB317_RS05855 (LB317_05865) | hslU | 1247760..1249163 (+) | 1404 | WP_000381629.1 | ATP-dependent protease ATPase subunit HslU | - |
| LB317_RS05860 (LB317_05870) | codY | 1249188..1249961 (+) | 774 | WP_000055333.1 | GTP-sensing pleiotropic transcriptional regulator CodY | - |
| LB317_RS05865 (LB317_05875) | rpsB | 1250238..1251005 (+) | 768 | WP_000268484.1 | 30S ribosomal protein S2 | - |
| LB317_RS05870 (LB317_05880) | - | 1251057..1251152 (+) | 96 | WP_225995268.1 | hypothetical protein | - |
| LB317_RS05875 (LB317_05885) | tsf | 1251187..1252068 (+) | 882 | WP_031786946.1 | translation elongation factor Ts | - |
| LB317_RS05880 (LB317_05890) | pyrH | 1252205..1252927 (+) | 723 | WP_000057330.1 | UMP kinase | - |
| LB317_RS05885 (LB317_05895) | frr | 1252946..1253500 (+) | 555 | WP_001280034.1 | ribosome recycling factor | - |
| LB317_RS05890 (LB317_05900) | - | 1253861..1254631 (+) | 771 | WP_000473698.1 | isoprenyl transferase | - |
| LB317_RS05895 (LB317_05905) | - | 1254638..1255420 (+) | 783 | WP_000868415.1 | phosphatidate cytidylyltransferase | - |
| LB317_RS05900 (LB317_05910) | rseP | 1255631..1256917 (+) | 1287 | WP_031786947.1 | RIP metalloprotease RseP | - |
| LB317_RS05905 (LB317_05915) | - | 1256937..1258640 (+) | 1704 | WP_031786948.1 | proline--tRNA ligase | - |
| LB317_RS05910 (LB317_05920) | - | 1258914..1263224 (+) | 4311 | WP_078097697.1 | PolC-type DNA polymerase III | - |
| LB317_RS05915 (LB317_05925) | rimP | 1263500..1263967 (+) | 468 | WP_031786950.1 | ribosome maturation factor RimP | - |
| LB317_RS05920 (LB317_05930) | nusA | 1263988..1265163 (+) | 1176 | WP_000097470.1 | transcription termination factor NusA | - |
| LB317_RS05925 (LB317_05935) | rnpM | 1265184..1265468 (+) | 285 | WP_031786951.1 | RNase P modulator RnpM | - |
| LB317_RS05930 (LB317_05940) | - | 1265465..1265782 (+) | 318 | WP_000021269.1 | YlxQ family RNA-binding protein | - |
| LB317_RS05935 (LB317_05945) | infB | 1265787..1267913 (+) | 2127 | WP_000043647.1 | translation initiation factor IF-2 | - |
| LB317_RS05940 (LB317_05950) | rbfA | 1268242..1268592 (+) | 351 | WP_000097321.1 | 30S ribosome-binding factor RbfA | - |
| LB317_RS05945 (LB317_05955) | truB | 1268763..1269680 (+) | 918 | WP_000282309.1 | tRNA pseudouridine(55) synthase TruB | - |
| LB317_RS05950 (LB317_05960) | ribF | 1269695..1270666 (+) | 972 | WP_031786952.1 | riboflavin biosynthesis protein RibF | - |
| LB317_RS05955 (LB317_05965) | rpsO | 1270781..1271050 (+) | 270 | WP_001018327.1 | 30S ribosomal protein S15 | - |
| LB317_RS05960 (LB317_05970) | pnp | 1271417..1273513 (+) | 2097 | WP_000076680.1 | polyribonucleotide nucleotidyltransferase | - |
| LB317_RS05965 (LB317_05975) | rnjB | 1273756..1275429 (+) | 1674 | WP_000052592.1 | ribonuclease J2 | - |
| LB317_RS05970 (LB317_05980) | - | 1275701..1278073 (+) | 2373 | WP_031786953.1 | FtsK/SpoIIIE family DNA translocase | - |
| LB317_RS05975 (LB317_05985) | - | 1278077..1278790 (+) | 714 | WP_001293301.1 | GntR family transcriptional regulator | - |
| LB317_RS05980 (LB317_05990) | yfmF | 1278821..1280086 (+) | 1266 | WP_031786954.1 | EF-P 5-aminopentanol modification-associated protein YfmF | - |
| LB317_RS05985 (LB317_05995) | yfmH | 1280086..1281372 (+) | 1287 | WP_031786955.1 | EF-P 5-aminopentanol modification-associated protein YfmH | - |
| LB317_RS05990 (LB317_06000) | ymfI | 1281372..1282076 (+) | 705 | WP_000646238.1 | elongation factor P 5-aminopentanone reductase | - |
| LB317_RS05995 (LB317_06005) | - | 1282184..1283011 (+) | 828 | WP_031786956.1 | DUF3388 domain-containing protein | - |
| LB317_RS06000 (LB317_06010) | - | 1283036..1283428 (+) | 393 | WP_000859442.1 | helix-turn-helix domain-containing protein | - |
| LB317_RS06005 (LB317_06015) | pgsA | 1283460..1284038 (+) | 579 | WP_031786957.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| LB317_RS06010 (LB317_06020) | - | 1284280..1285431 (+) | 1152 | WP_031786958.1 | CinA family nicotinamide mononucleotide deamidase-related protein | - |
| LB317_RS06015 (LB317_06025) | recA | 1285596..1286639 (+) | 1044 | WP_000368169.1 | recombinase RecA | Machinery gene |
| LB317_RS06020 (LB317_06030) | - | 1286821..1286966 (-) | 146 | Protein_1177 | ISL3 family transposase | - |
Sequence
Protein
Download Length: 290 a.a. Molecular weight: 33128.01 Da Isoelectric Point: 9.3910
>NTDB_id=608018 LB317_RS05830 WP_031786943.1 1241258..1242130(+) (dprA) [Staphylococcus argenteus strain 1801221]
MLNQILLKLIWSHFTTSQIHQLFNKFPNFLEVDELEQNYLLRKFVLNNSNENLSIKNEVYSRISFDEIMSNIQQSKLNFI
TCFDKGYPSYLKEIYDYPFVLFYKGSINILSSPKALAVVGSRVSSNYTTKALNHLFYSFQQSNLTIVSGLAQGADAMAHQ
TALKYNLPTIAVLAFGHQTHYPKSTRALRNKIEEKGLVISEYPPHTPIARYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDILEDYFI
MLNQILLKLIWSHFTTSQIHQLFNKFPNFLEVDELEQNYLLRKFVLNNSNENLSIKNEVYSRISFDEIMSNIQQSKLNFI
TCFDKGYPSYLKEIYDYPFVLFYKGSINILSSPKALAVVGSRVSSNYTTKALNHLFYSFQQSNLTIVSGLAQGADAMAHQ
TALKYNLPTIAVLAFGHQTHYPKSTRALRNKIEEKGLVISEYPPHTPIARYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDILEDYFI
Nucleotide
Download Length: 873 bp
>NTDB_id=608018 LB317_RS05830 WP_031786943.1 1241258..1242130(+) (dprA) [Staphylococcus argenteus strain 1801221]
ATGTTAAATCAAATTCTACTTAAATTAATTTGGAGTCATTTTACAACTTCGCAAATTCACCAGCTATTTAATAAATTTCC
AAACTTTTTAGAAGTAGATGAACTTGAACAAAATTATCTACTACGCAAATTTGTTTTAAATAATTCAAATGAGAATCTTT
CGATTAAAAATGAGGTTTATAGTCGAATTTCTTTTGATGAAATAATGTCAAATATCCAACAAAGCAAATTGAACTTTATA
ACTTGTTTTGATAAAGGGTATCCTAGTTACTTAAAAGAAATTTACGACTATCCATTTGTTTTATTTTATAAAGGGAGTAT
TAATATCCTCAGTTCTCCTAAAGCATTAGCTGTAGTTGGTTCGAGAGTTTCAAGCAATTATACAACAAAAGCATTGAACC
ATCTTTTCTATTCGTTCCAACAATCAAATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ACAGCATTAAAATACAATCTCCCTACAATAGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACACGAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTGATATCCGAATATCCACCGCATACACCAATTGCTAGATATAGATTTC
CAGAACGAAATAGAATTATCAGTGGGTTGTCAAAAGGGGTTCTAATAACAGAAGCTAAAGAACAAAGTGGTAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAACAGAAATGTTTATGTTTTACCAGGATCAATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGAGCTAAGGTAGTTTTAAACGCTAATGATATATTAGAAGATTACTTTATTTAA
ATGTTAAATCAAATTCTACTTAAATTAATTTGGAGTCATTTTACAACTTCGCAAATTCACCAGCTATTTAATAAATTTCC
AAACTTTTTAGAAGTAGATGAACTTGAACAAAATTATCTACTACGCAAATTTGTTTTAAATAATTCAAATGAGAATCTTT
CGATTAAAAATGAGGTTTATAGTCGAATTTCTTTTGATGAAATAATGTCAAATATCCAACAAAGCAAATTGAACTTTATA
ACTTGTTTTGATAAAGGGTATCCTAGTTACTTAAAAGAAATTTACGACTATCCATTTGTTTTATTTTATAAAGGGAGTAT
TAATATCCTCAGTTCTCCTAAAGCATTAGCTGTAGTTGGTTCGAGAGTTTCAAGCAATTATACAACAAAAGCATTGAACC
ATCTTTTCTATTCGTTCCAACAATCAAATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ACAGCATTAAAATACAATCTCCCTACAATAGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACACGAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTGATATCCGAATATCCACCGCATACACCAATTGCTAGATATAGATTTC
CAGAACGAAATAGAATTATCAGTGGGTTGTCAAAAGGGGTTCTAATAACAGAAGCTAAAGAACAAAGTGGTAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAACAGAAATGTTTATGTTTTACCAGGATCAATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGAGCTAAGGTAGTTTTAAACGCTAATGATATATTAGAAGATTACTTTATTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Staphylococcus aureus MW2 |
67.123 |
100 |
0.676 |
| dprA | Staphylococcus aureus N315 |
67.123 |
100 |
0.676 |
| dprA/cilB/dalA | Streptococcus pneumoniae Rx1 |
37.722 |
96.897 |
0.366 |
| dprA/cilB/dalA | Streptococcus pneumoniae D39 |
37.722 |
96.897 |
0.366 |
| dprA/cilB/dalA | Streptococcus pneumoniae R6 |
37.722 |
96.897 |
0.366 |
| dprA/cilB/dalA | Streptococcus pneumoniae TIGR4 |
37.722 |
96.897 |
0.366 |
| dprA/cilB/dalA | Streptococcus mitis SK321 |
37.722 |
96.897 |
0.366 |
| dprA/cilB/dalA | Streptococcus mitis NCTC 12261 |
37.367 |
96.897 |
0.362 |