NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	NLY78_RS05020	Genome accession	NZ_CP100435
Coordinates	1022355..1023026 (-)	Length	223 a.a.
NCBI ID	WP_009909965.1	Uniprot ID	-
Organism	Streptococcus suis strain DE609B
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1017355..1028026

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY78_RS05000 (NLY78_04995)	rpsT	1018155..1018403 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
NLY78_RS05005 (NLY78_05000)	tnpA	1018545..1019009 (-)	465	WP_012775157.1	IS200/IS605-like element ISSsu4 family transposase	-
NLY78_RS05010 (NLY78_05005)	-	1019423..1020652 (-)	1230	WP_012027071.1	transglutaminase domain-containing protein	-
NLY78_RS05015 (NLY78_05010)	ciaH	1020983..1022362 (-)	1380	WP_012027074.1	cell wall metabolism sensor histidine kinase WalK	Regulator
NLY78_RS05020 (NLY78_05015)	ciaR	1022355..1023026 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
NLY78_RS05025 (NLY78_05020)	-	1023220..1023600 (-)	381	WP_012027076.1	hypothetical protein	-
NLY78_RS05030 (NLY78_05025)	-	1023985..1025187 (+)	1203	WP_012775158.1	IS110 family transposase	-
NLY78_RS05035 (NLY78_05030)	phoU	1025389..1026045 (-)	657	WP_012028219.1	phosphate signaling complex protein PhoU	-
NLY78_RS05040 (NLY78_05035)	pstB	1026074..1026832 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
NLY78_RS05045 (NLY78_05040)	pstB	1026844..1027647 (-)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25290.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=605307 NLY78_RS05020 WP_009909965.1 1022355..1023026(-) (ciaR) [Streptococcus suis strain DE609B]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=605307 NLY78_RS05020 WP_009909965.1 1022355..1023026(-) (ciaR) [Streptococcus suis strain DE609B]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT

TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363

Detailed information NTG0605307