Detailed information NTG0603115

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: K8O83_RS02525
• Genome accession: NZ_CP082857
• Coordinates: 455379..456716 (+)
• Length: 445 a.a.
• NCBI ID: WP_006995132.1
• Uniprot ID: -
• Organism: Haemophilus aegyptius strain FDAARGOS_1478
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 450379..461716

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8O83_RS02500 (K8O83_02455)	-	450438..453038 (-)	2601	WP_006995137.1	penicillin-binding protein 1A	-
K8O83_RS02505 (K8O83_02460)	-	453137..453934 (+)	798	Protein_466	competence protein ComA	-
K8O83_RS02510 (K8O83_02465)	comB	453935..454441 (+)	507	WP_006995134.1	competence protein ComB	Machinery gene
K8O83_RS02515 (K8O83_02470)	comC	454438..454959 (+)	522	WP_005662592.1	competence protein ComC	Machinery gene
K8O83_RS02520 (K8O83_02475)	comD	454956..455369 (+)	414	WP_006995133.1	pilus assembly protein PilP	Machinery gene
K8O83_RS02525 (K8O83_02480)	comE	455379..456716 (+)	1338	WP_006995132.1	type IV pilus secretin PilQ	Machinery gene
K8O83_RS02530 (K8O83_02485)	-	456729..457415 (+)	687	WP_006995131.1	ComF family protein	-
K8O83_RS02535 (K8O83_02490)	nfuA	457491..458087 (+)	597	WP_006995130.1	Fe-S biogenesis protein NfuA	-
K8O83_RS02540 (K8O83_02495)	nudC	458154..458949 (+)	796	Protein_473	NAD(+) diphosphatase	-
K8O83_RS02545 (K8O83_02500)	-	458985..459575 (+)	591	WP_006995127.1	YjaG family protein	-
K8O83_RS02550 (K8O83_02505)	-	459715..459987 (+)	273	WP_006995126.1	HU family DNA-binding protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49084.31 Da
• Isoelectric Point: 8.2628

>NTDB_id=603115 K8O83_RS02525 WP_006995132.1 455379..456716(+) (comE) [Haemophilus aegyptius strain FDAARGOS_1478]
MKKYLLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSSTGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEGVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide

• Length: 1338 bp

>NTDB_id=603115 K8O83_RS02525 WP_006995132.1 455379..456716(+) (comE) [Haemophilus aegyptius strain FDAARGOS_1478]
ATGAAGAAATATCTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACACTGGAGCAATTAGCTTTCCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTTCTACGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCATTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGTACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGGGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (269-429)

• Bacterial type II/III secretion system short domain (Secretin_N) (123-187)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae 86-028NP	98.876	100	0.989
comE	Haemophilus influenzae Rd KW20	97.303	100	0.973
comE	Glaesserella parasuis strain SC1401	52.235	95.506	0.499
pilQ	Vibrio campbellii strain DS40M4	42.959	94.157	0.404
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	42.233	92.584	0.391
pilQ	Vibrio cholerae strain A1552	42.233	92.584	0.391