Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   NC516_RS00370 Genome accession   NZ_CP099485
Coordinates   71271..72530 (+) Length   419 a.a.
NCBI ID   WP_025016471.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain WiKim0095     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 66271..77530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NC516_RS00355 (NC516_00355) yycH 68139..69470 (+) 1332 WP_035147594.1 two-component system activity regulator YycH -
  NC516_RS00360 (NC516_00360) - 69475..70296 (+) 822 WP_035147596.1 two-component system regulatory protein YycI -
  NC516_RS00365 (NC516_00365) vicX 70331..71137 (+) 807 WP_016264363.1 MBL fold metallo-hydrolase Regulator
  NC516_RS00370 (NC516_00370) htrA 71271..72530 (+) 1260 WP_025016471.1 trypsin-like peptidase domain-containing protein Regulator
  NC516_RS00375 (NC516_00375) rlmH 73074..73553 (+) 480 WP_011373797.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  NC516_RS00380 (NC516_00380) - 73693..74352 (+) 660 WP_025016470.1 hypothetical protein -
  NC516_RS00385 (NC516_00385) add 74409..75434 (-) 1026 WP_035147601.1 adenosine deaminase -
  NC516_RS00390 (NC516_00390) - 75613..76947 (+) 1335 WP_025016468.1 NCS2 family permease -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 42698.80 Da        Isoelectric Point: 9.4566

>NTDB_id=601433 NC516_RS00370 WP_025016471.1 71271..72530(+) (htrA) [Latilactobacillus sakei strain WiKim0095]
MNQNSGLMKTAVVAVISALIGGGAAYAGFSRLGSSANDVTTATQTPTKAGATKISNIKVNSSSQTTTAFQKVNTSVVSVV
NLQKQQQSTGDLSSLFGSGSTNSNSSSSKSSSSDLEESSEGSGLIYEKKDGKAYIVTNNHVVAGSDKIEVILSDGTKLEA
SLVGTDAVSDLAVLKINGTKVKKTATFGDSDSIKAGESVLAIGSPLGSEYATSVTQGIISAKKRTIDVTDETTGQTTGQA
TVIQTDTAINPGNSGGPLVNMAGQVVGINSMKLASNGDTTVEGMGFAIPSNEVVKIINQLVANGKVVRPALGISVIDLTN
ISSTQQSSVLKLPSTVNSGVVVASVTSNSVAKKAGISKYDVIVGLGGKTVSSVADLHTILYSYAMNSTTEIQYYHNGSLK
KANVKLTQAASSDSTTTTK

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=601433 NC516_RS00370 WP_025016471.1 71271..72530(+) (htrA) [Latilactobacillus sakei strain WiKim0095]
ATGAATCAAAATTCAGGATTAATGAAAACAGCGGTTGTTGCAGTTATTTCAGCATTGATTGGTGGGGGCGCAGCCTATGC
CGGTTTTTCTCGACTCGGCAGTTCGGCCAATGATGTCACGACTGCAACGCAGACGCCTACTAAAGCGGGGGCAACTAAGA
TTAGTAATATCAAAGTGAACTCATCATCACAGACGACAACAGCCTTCCAAAAGGTTAATACATCAGTTGTATCCGTTGTG
AACTTACAAAAACAACAACAATCAACCGGTGACCTGAGTTCATTATTTGGTTCAGGCAGCACCAACAGCAATAGTAGTTC
TTCTAAGAGCAGTAGCAGTGATTTAGAAGAATCCAGTGAAGGTTCAGGTTTAATCTACGAGAAAAAAGACGGCAAAGCTT
ACATCGTGACGAATAATCACGTGGTTGCTGGTTCTGATAAAATCGAAGTCATTTTGAGTGATGGCACAAAATTGGAAGCT
AGTTTAGTTGGGACAGATGCTGTTTCTGATTTGGCTGTCTTAAAAATTAACGGGACTAAAGTGAAGAAGACGGCAACGTT
TGGTGATTCAGATAGTATCAAAGCTGGTGAATCAGTTCTTGCGATCGGCTCACCATTGGGTTCAGAATACGCAACTTCTG
TCACACAAGGGATCATTTCTGCTAAGAAACGGACAATTGATGTGACGGACGAAACAACTGGCCAAACAACTGGTCAAGCG
ACTGTTATTCAAACTGATACAGCGATTAACCCTGGGAACTCAGGTGGCCCATTAGTTAATATGGCCGGTCAAGTTGTTGG
GATTAATTCAATGAAGTTAGCCTCAAATGGTGATACGACAGTTGAAGGGATGGGCTTTGCTATTCCAAGTAACGAAGTTG
TTAAAATTATTAATCAATTAGTGGCTAACGGGAAAGTCGTTAGACCAGCACTTGGGATTAGTGTGATAGATTTAACCAAT
ATTTCATCAACACAACAATCTTCAGTATTAAAACTACCATCAACCGTCAATAGCGGGGTAGTGGTTGCCTCAGTAACAAG
CAATTCAGTTGCTAAGAAAGCTGGGATTAGTAAATACGATGTGATTGTCGGTTTAGGCGGCAAGACGGTTTCAAGCGTTG
CAGACTTACACACAATCCTATACAGTTACGCGATGAATAGTACAACTGAAATTCAGTACTACCATAATGGCAGCTTGAAA
AAAGCGAATGTTAAACTTACACAAGCAGCTTCATCAGATAGTACGACAACAACTAAATAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(284-413)

PDZ domain (PDZ_2)

(309-406)

Trypsin-like peptidase domain (Trypsin_2)

(121-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

45.209

97.136

0.439
  htrA Streptococcus gordonii str. Challis substr. CH1

42.512

98.807

0.42
  htrA Streptococcus mutans UA159

45.968

88.783

0.408
  htrA Streptococcus pneumoniae TIGR4

48.424

83.294

0.403
  htrA Streptococcus pneumoniae R6

48.424

83.294

0.403
  htrA Streptococcus pneumoniae Rx1

48.424

83.294

0.403
  htrA Streptococcus pneumoniae D39

48.424

83.294

0.403