Detailed information NTG0600131

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: K6973_RS11170
• Genome accession: NZ_CP082206
• Coordinates: 2253823..2255043 (+)
• Length: 406 a.a.
• NCBI ID: WP_138126917.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain DY107
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2248823..2260043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6973_RS11140 (K6973_11140)	-	2250442..2251536 (+)	1095	WP_222819415.1	IS30 family transposase	-
K6973_RS11145 (K6973_11145)	-	2251800..2251991 (+)	192	WP_017766886.1	hypothetical protein	-
K6973_RS11150 (K6973_11150)	-	2251991..2252359 (+)	369	WP_261987943.1	hypothetical protein	-
K6973_RS11155 (K6973_11155)	-	2252432..2252614 (+)	183	Protein_2162	hypothetical protein	-
K6973_RS11165 (K6973_11165)	rlmH	2253134..2253613 (-)	480	WP_218654958.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
K6973_RS11170 (K6973_11170)	htrA	2253823..2255043 (+)	1221	WP_138126917.1	trypsin-like peptidase domain-containing protein	Regulator
K6973_RS11175 (K6973_11175)	spo0J	2255158..2255931 (+)	774	WP_218654960.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 42856.29 Da
• Isoelectric Point: 5.2394

>NTDB_id=600131 K6973_RS11170 WP_138126917.1 2253823..2255043(+) (htrA) [Streptococcus dysgalactiae strain DY107]
MPSMKHILKSLGILLIGFLGGLLAIFTFNATQQSSSTSHTGSATTSEMVFNNTTDTTKAVKVVQNAVVSVINYQADPSSS
ISNPYTKLFGEDQTRENKDTELSIFREGSGVIYRKNGDSAYVITNNHVIDGAKRIEILMADGTKVIGELVGADTYSDLAV
VKVASDKIETVAKFADSTKLNVGEVAIAIGSPLGTQYANSVTEGIVSSLSRTVTLKNEDGDTVSTNAIQTDAAINPGNSG
GPLINIEGQVIGINSSKISSTPAGDNGNRGSIEGIGFAIPSSDVVKIIKQLEKYGEVIRPALGIHMVNLNDLSTNALYEI
NIPTGVTGGIVVASVQDGMPASGKLAQYDVITEIDGKAVNSISDLQSNLYGHDINDTIKVTFYRGTTKKKADITLTKTTQ
DLTKKQ

Nucleotide

• Length: 1221 bp

>NTDB_id=600131 K6973_RS11170 WP_138126917.1 2253823..2255043(+) (htrA) [Streptococcus dysgalactiae strain DY107]
ATGCCATCTATGAAACATATCTTAAAATCCTTAGGCATTTTACTCATTGGATTTTTAGGAGGATTGTTAGCAATTTTCAC
CTTTAATGCTACTCAACAGTCTTCCTCTACCTCACATACTGGTAGTGCGACGACGAGTGAGATGGTTTTTAATAATACTA
CTGATACAACGAAAGCGGTTAAAGTCGTTCAAAATGCAGTAGTATCAGTGATTAACTATCAAGCAGATCCTTCTTCATCT
ATTTCAAATCCCTACACAAAACTCTTTGGAGAAGATCAAACAAGAGAAAATAAAGATACCGAGTTATCTATTTTTAGAGA
GGGTTCTGGTGTTATTTATCGAAAAAATGGTGATTCTGCGTACGTTATTACTAATAATCATGTCATTGACGGTGCAAAGC
GAATTGAAATTCTTATGGCAGATGGAACCAAAGTCATAGGAGAGTTAGTTGGAGCTGATACATATTCTGACTTGGCGGTT
GTTAAAGTTGCCTCAGATAAAATTGAGACAGTTGCTAAATTTGCAGATTCTACTAAGCTTAATGTTGGAGAAGTTGCTAT
CGCAATCGGTAGCCCACTAGGAACTCAGTACGCCAATTCCGTTACAGAAGGAATTGTTTCTAGTCTCAGTCGTACCGTTA
CCTTAAAAAATGAAGATGGGGACACTGTTTCAACAAATGCCATTCAAACTGATGCTGCTATTAATCCTGGAAACTCTGGT
GGTCCCCTTATTAATATTGAAGGACAGGTTATTGGTATCAATTCAAGTAAAATTTCTTCTACACCTGCTGGAGATAACGG
TAATAGAGGATCTATTGAAGGTATTGGATTTGCAATCCCATCTAGTGATGTTGTTAAAATAATCAAGCAATTAGAGAAGT
ATGGTGAAGTCATTAGACCAGCCCTTGGAATTCATATGGTCAACTTAAATGACTTATCTACTAATGCTCTCTATGAAATC
AATATCCCTACGGGTGTAACTGGTGGGATTGTGGTCGCTTCTGTTCAAGATGGAATGCCAGCTAGTGGTAAACTTGCCCA
GTACGACGTTATTACTGAAATTGATGGTAAAGCCGTCAACTCAATCAGTGATCTTCAAAGCAACCTATACGGCCATGACA
TTAACGATACCATCAAGGTAACCTTTTATAGAGGGACAACCAAGAAAAAAGCAGATATTACCTTAACTAAAACAACCCAG
GATTTGACCAAAAAGCAGTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	58.458	99.015	0.579
htrA	Streptococcus mitis NCTC 12261	53.563	100	0.537
htrA	Streptococcus pneumoniae Rx1	53.563	100	0.537
htrA	Streptococcus pneumoniae D39	53.563	100	0.537
htrA	Streptococcus pneumoniae R6	53.563	100	0.537
htrA	Streptococcus pneumoniae TIGR4	53.563	100	0.537
htrA	Streptococcus gordonii str. Challis substr. CH1	53.465	99.507	0.532