Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   K6973_RS06060 Genome accession   NZ_CP082206
Coordinates   1179527..1180201 (-) Length   224 a.a.
NCBI ID   WP_129555678.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain DY107     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1174527..1185201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6973_RS06035 (K6973_06035) - 1174712..1175989 (-) 1278 WP_222819131.1 pyrimidine-nucleoside phosphorylase -
  K6973_RS06040 (K6973_06040) - 1175976..1176575 (-) 600 WP_281429827.1 class I SAM-dependent methyltransferase -
  K6973_RS06045 (K6973_06045) coaA 1176844..1177764 (+) 921 WP_218654538.1 type I pantothenate kinase -
  K6973_RS06050 (K6973_06050) rpsT 1177818..1178066 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  K6973_RS06055 (K6973_06055) ciaH 1178224..1179534 (-) 1311 WP_218654539.1 HAMP domain-containing sensor histidine kinase Regulator
  K6973_RS06060 (K6973_06060) ciaR 1179527..1180201 (-) 675 WP_129555678.1 response regulator transcription factor Regulator
  K6973_RS06065 (K6973_06065) - 1180405..1182942 (-) 2538 WP_222819133.1 M1 family metallopeptidase -
  K6973_RS06070 (K6973_06070) phoU 1183143..1183796 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  K6973_RS06075 (K6973_06075) pstB 1183874..1184632 (-) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25573.52 Da        Isoelectric Point: 4.4123

>NTDB_id=600111 K6973_RS06060 WP_129555678.1 1179527..1180201(-) (ciaR) [Streptococcus dysgalactiae strain DY107]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGQPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=600111 K6973_RS06060 WP_129555678.1 1179527..1180201(-) (ciaR) [Streptococcus dysgalactiae strain DY107]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTATTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTTACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGTAACGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCAGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

35.443

100

0.375