Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   K6973_RS06055 Genome accession   NZ_CP082206
Coordinates   1178224..1179534 (-) Length   436 a.a.
NCBI ID   WP_218654539.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain DY107     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1173224..1184534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6973_RS06025 (K6973_06025) - 1173658..1174047 (-) 390 WP_022554672.1 cytidine deaminase -
  K6973_RS06030 (K6973_06030) deoC 1174034..1174696 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  K6973_RS06035 (K6973_06035) - 1174712..1175989 (-) 1278 WP_222819131.1 pyrimidine-nucleoside phosphorylase -
  K6973_RS06040 (K6973_06040) - 1175976..1176575 (-) 600 WP_281429827.1 class I SAM-dependent methyltransferase -
  K6973_RS06045 (K6973_06045) coaA 1176844..1177764 (+) 921 WP_218654538.1 type I pantothenate kinase -
  K6973_RS06050 (K6973_06050) rpsT 1177818..1178066 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  K6973_RS06055 (K6973_06055) ciaH 1178224..1179534 (-) 1311 WP_218654539.1 HAMP domain-containing sensor histidine kinase Regulator
  K6973_RS06060 (K6973_06060) ciaR 1179527..1180201 (-) 675 WP_129555678.1 response regulator transcription factor Regulator
  K6973_RS06065 (K6973_06065) - 1180405..1182942 (-) 2538 WP_222819133.1 M1 family metallopeptidase -
  K6973_RS06070 (K6973_06070) phoU 1183143..1183796 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49952.52 Da        Isoelectric Point: 8.2375

>NTDB_id=600110 K6973_RS06055 WP_218654539.1 1178224..1179534(-) (ciaH) [Streptococcus dysgalactiae strain DY107]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLMNFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRIDKARTRQTG
GFGLGLSLAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=600110 K6973_RS06055 WP_218654539.1 1178224..1179534(-) (ciaH) [Streptococcus dysgalactiae strain DY107]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATATACCCATTTTTTTCATTTTTTTGCGGTCTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGCAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCTTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGACGCTTTTTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACCACTAGCCTGATGAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATTATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTACGAAAAACAAAAAATGTTTGTGGAAAATGCCAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGACGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCATTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGTCCTTAGCTCAACAAATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.37

100

0.516
  ciaH Streptococcus pneumoniae D39

51.37

100

0.516
  ciaH Streptococcus pneumoniae R6

51.37

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.37

100

0.516