Detailed information NTG0600098

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: K6973_RS03280
• Genome accession: NZ_CP082206
• Coordinates: 611744..613096 (+)
• Length: 450 a.a.
• NCBI ID: WP_003049953.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain DY107
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 606744..618096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6973_RS03255 (K6973_03255)	-	607811..608458 (-)	648	WP_138125097.1	amino acid ABC transporter permease	-
K6973_RS03260 (K6973_03260)	-	608473..609174 (-)	702	WP_138125099.1	amino acid ABC transporter permease	-
K6973_RS03265 (K6973_03265)	-	609188..609988 (-)	801	WP_138125101.1	transporter substrate-binding domain-containing protein	-
K6973_RS03270 (K6973_03270)	-	609988..610782 (-)	795	WP_003057217.1	amino acid ABC transporter ATP-binding protein	-
K6973_RS03275 (K6973_03275)	vicR	611041..611751 (+)	711	WP_003049952.1	response regulator YycF	Regulator
K6973_RS03280 (K6973_03280)	vicK	611744..613096 (+)	1353	WP_003049953.1	cell wall metabolism sensor histidine kinase VicK	Regulator
K6973_RS03285 (K6973_03285)	vicX	613100..613909 (+)	810	WP_138125103.1	MBL fold metallo-hydrolase	Regulator
K6973_RS03290 (K6973_03290)	rnc	614182..614874 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.02 Da
• Isoelectric Point: 5.5557

>NTDB_id=600098 K6973_RS03280 WP_003049953.1 611744..613096(+) (vicK) [Streptococcus dysgalactiae strain DY107]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=600098 K6973_RS03280 WP_003049953.1 611744..613096(+) (vicK) [Streptococcus dysgalactiae strain DY107]
ATGACTAGAGATATCATCGGGAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGCAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTTGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAGTCCTACTTGGAGGCTCTTGACGAAGGTGCCCTCAAG
GAAGATATTGCCCCAAGTTTTATCAAGGTTTCTCTTGACGAAACCAATCGGATGATGCGAATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTTGAGATGACCAATTTTACAGCTTTTATGACGTCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACTTCT
GTTTGGCTGGAAATTGATAACGATAAGATGACGCAGGTTATTGAAAATATCTTAAACAATGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACAGACACGCAATTGATTATTTCCATCTCAGACCAAGGTTTAGGCATTC
CGAAGAAGGACCTGCCCCTTATTTTTGACCGTTTTTACCGAGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATCTGGGCGAAAAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-165)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.671	92	0.678
micB	Streptococcus pneumoniae Cp1015	66.824	94.444	0.631