NTDB

Overview

Name	micA	Type	Regulator
Locus tag	K6974_RS09495	Genome accession	NZ_CP082204
Coordinates	1902878..1903582 (-)	Length	234 a.a.
NCBI ID	WP_024416283.1	Uniprot ID	-
Organism	Streptococcus suis strain FJSM5
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1897878..1908582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6974_RS09480 (K6974_09385)	vga(F)	1899083..1900468 (-)	1386	WP_238140365.1	ABC-F type ribosomal protection protein Vga(F)	-
K6974_RS09485 (K6974_09390)	vicX	1900726..1901529 (-)	804	WP_222337255.1	MBL fold metallo-hydrolase	Regulator
K6974_RS09490 (K6974_09395)	micB	1901536..1902885 (-)	1350	WP_002935841.1	cell wall metabolism sensor histidine kinase VicK	Regulator
K6974_RS09495 (K6974_09400)	micA	1902878..1903582 (-)	705	WP_024416283.1	response regulator YycF	Regulator
K6974_RS09500 (K6974_09405)	-	1903776..1904537 (+)	762	WP_002935839.1	amino acid ABC transporter ATP-binding protein	-
K6974_RS09505 (K6974_09410)	-	1904548..1905387 (+)	840	WP_222337254.1	transporter substrate-binding domain-containing protein	-
K6974_RS09510 (K6974_09415)	-	1905402..1906100 (+)	699	WP_222337253.1	amino acid ABC transporter permease	-
K6974_RS09515 (K6974_09420)	-	1906115..1906774 (+)	660	WP_029944404.1	amino acid ABC transporter permease	-
K6974_RS09520 (K6974_09425)	-	1906897..1907184 (+)	288	WP_029185561.1	acyltransferase family protein	-
K6974_RS09525 (K6974_09430)	-	1907148..1907942 (+)	795	WP_277944635.1	acyltransferase family protein	-

Sequence

Protein

Download Length: 234 a.a. Molecular weight: 26767.75 Da Isoelectric Point: 4.8957

                                >NTDB_id=600001 K6974_RS09495 WP_024416283.1 1902878..1903582(-) (micA) [Streptococcus suis strain FJSM5]

MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFESEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA

KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT

HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide

Download Length: 705 bp

                                >NTDB_id=600001 K6974_RS09495 WP_024416283.1 1902878..1903582(-) (micA) [Streptococcus suis strain FJSM5]

ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA

AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGTCTGAGTTTCCTGACATTGTCATTTTGGACTTGA

TGTTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT

AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA

ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC

CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC

CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT

TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC

CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
micA	Streptococcus pneumoniae Cp1015	81.116	99.573	0.808
vicR	Streptococcus mutans UA159	80	100	0.803
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.217	98.291	0.444
covR	Streptococcus salivarius strain HSISS4	43.723	98.718	0.432
scnR	Streptococcus mutans UA159	38.095	98.718	0.376

Detailed information NTG0600001