Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   K6974_RS01275 Genome accession   NZ_CP082204
Coordinates   236725..238878 (-) Length   717 a.a.
NCBI ID   WP_222336628.1    Uniprot ID   -
Organism   Streptococcus suis strain FJSM5     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 231725..243878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6974_RS01245 (K6974_01230) - 231781..232086 (+) 306 WP_222336630.1 hypothetical protein -
  K6974_RS01250 (K6974_01235) - 232490..232831 (+) 342 WP_024398112.1 LytTR family DNA-binding domain-containing protein -
  K6974_RS01255 (K6974_01240) comE/blpR 232831..233571 (+) 741 WP_024398111.1 response regulator transcription factor Regulator
  K6974_RS01260 (K6974_01245) - 233581..234912 (+) 1332 WP_044773740.1 sensor histidine kinase -
  K6974_RS01265 (K6974_01250) - 235107..235256 (-) 150 WP_172034621.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  K6974_RS01270 (K6974_01255) - 235354..236715 (-) 1362 WP_222336629.1 bacteriocin secretion accessory protein -
  K6974_RS01275 (K6974_01260) comA/nlmT 236725..238878 (-) 2154 WP_222336628.1 peptide cleavage/export ABC transporter Regulator
  K6974_RS01280 (K6974_01265) - 239210..239449 (+) 240 WP_222336627.1 bacteriocin -
  K6974_RS01285 (K6974_01270) - 239462..239674 (+) 213 WP_024398104.1 Blp family class II bacteriocin -
  K6974_RS01290 (K6974_01275) - 239689..239919 (+) 231 WP_024398103.1 hypothetical protein -
  K6974_RS01295 (K6974_01280) - 240220..240828 (+) 609 WP_024398100.1 CPBP family intramembrane glutamic endopeptidase -
  K6974_RS01300 (K6974_01285) - 241019..241273 (+) 255 WP_228381684.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  K6974_RS01305 (K6974_01290) - 241291..241617 (+) 327 WP_024398098.1 hypothetical protein -
  K6974_RS01310 (K6974_01295) - 241839..242471 (+) 633 WP_053042444.1 CPBP family intramembrane glutamic endopeptidase -
  K6974_RS01315 (K6974_01300) - 242843..243301 (+) 459 WP_222336625.1 CPBP family intramembrane glutamic endopeptidase -
  K6974_RS01320 (K6974_01305) - 243451..243666 (+) 216 WP_222336623.1 hypothetical protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80391.43 Da        Isoelectric Point: 6.7854

>NTDB_id=599978 K6974_RS01275 WP_222336628.1 236725..238878(-) (comA/nlmT) [Streptococcus suis strain FJSM5]
MTKIKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAHEMGFETRAIQADMSLFDMTDI
PYPFIVHVNKEGKLQHYYVVYKNLKDQILIGDPDPTVKVTKMSKERFASEWTGVAIFLAPEPSYKPHKDKKNGLLDFLPL
IFQQRTLIFYIVLASLLVTLINIAGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMTFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVTILTIVGGVLLVQNTHLFLLSLISIPIYVV
IIFAFIKPFERMNNAVMQSNSMVSSAIIEDINGIETIKSLTSEEQRYQKIDSEFVDYLEKSFILSKYSILQSTLKQGAQL
ILNIAILWLGSQLVMTGKISIGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFQEGQTLTDPSFL
KGDIQFDDVSYKYGFGRDTLSDIQLTIKEGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITLNHNDLKMVDKKVLRQYI
NYLPQQAYIFSGSILDNLTLGANQAISQEDILKACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMAMTDKTIIFVAHRLSISERTNQVIVLDQGKIIETGSHQELMSRGGFYHHLFSK

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=599978 K6974_RS01275 WP_222336628.1 236725..238878(-) (comA/nlmT) [Streptococcus suis strain FJSM5]
ATGACCAAGATAAAGAAAACCTTCGTCCCTCAGATAGATGCCCGAGATTGCGGAGTCGCTGCTCTCGCTTCTATCGCCAA
ATACTACGGCTCAGACTACTCCTTGGCCCACTTGCGAGAGTTAGCAAAGACTAATAAAGAAGGAACAACAGCCCTCGGTA
TCGTGAAAGCTGCACATGAAATGGGCTTTGAAACCAGGGCTATCCAGGCTGATATGAGCCTCTTTGACATGACCGATATT
CCTTATCCCTTCATCGTCCATGTCAATAAAGAAGGAAAACTCCAGCATTACTATGTGGTCTATAAAAATTTGAAAGATCA
GATCCTCATTGGCGATCCCGACCCGACTGTAAAAGTTACCAAGATGAGCAAGGAGCGATTCGCTTCCGAATGGACAGGAG
TGGCCATTTTTCTCGCACCTGAACCGAGCTATAAACCGCACAAGGATAAAAAAAATGGCCTGCTCGACTTCCTTCCCCTC
ATCTTCCAACAACGAACACTTATCTTTTATATCGTTCTAGCCAGCTTACTCGTCACTCTCATCAACATTGCTGGCTCCTA
CTATCTGCAAGGGATTTTAGATGAATACATTCCAAACCAGATGAAATCTACTCTCGGCATCATCTCCATCGGACTGATTA
TCACCTACATCCTCCAACAAATGATGACCTTCTCCAGAGACTACCTATTAACTGTCCTCAGTCAACGGCTCAGCATTGAT
GTCATTCTCTCCTATATCCGACACATCTTCGAACTCCCTATGTCCTTCTTTGCGACACGTCGGACAGGTGAAGTCATCTC
TCGTTTTACAGATGCCAACTCAATCATCGATGCCTTGGCCTCTACAATCCTCTCCCTCTTCCTAGATGTGACTATTCTAA
CCATTGTGGGTGGGGTCTTATTGGTACAAAACACGCACCTCTTCCTCCTCTCACTGATTTCAATCCCAATCTACGTGGTC
ATCATCTTTGCCTTTATTAAACCCTTTGAAAGAATGAACAACGCTGTTATGCAGAGTAATTCGATGGTAAGCTCTGCTAT
TATCGAAGATATCAATGGTATTGAGACCATTAAGTCATTGACAAGCGAAGAACAACGCTACCAAAAGATTGACAGCGAAT
TTGTGGATTATCTGGAAAAATCCTTTATCCTCAGCAAATATTCGATCCTGCAATCCACTCTGAAGCAAGGAGCCCAGCTG
ATACTCAACATTGCTATTCTCTGGCTCGGCTCTCAACTAGTTATGACAGGAAAAATCTCTATCGGACAACTCATCACCTT
CAATACCCTCCTCTCTTACTTCACCAATCCTTTGGAAAATATCATCAACCTCCAGACCAAACTCCAATCTGCCAAAGTAG
CCAACAATCGCCTTAATGAAGTCTACTTGGTTGAATCAGAATTTCAAGAAGGACAGACCCTAACCGATCCAAGCTTCTTA
AAAGGAGATATTCAGTTTGACGATGTTTCCTATAAATACGGATTTGGACGAGACACCCTATCTGATATTCAACTGACCAT
CAAAGAAGGGGACAAGGTTAGTTTAGTCGGTATCAGCGGCTCTGGAAAAACAACACTAGCTAAAATGATTGTGAACTTTT
TTGAGCCCTATAAGGGACGCATCACGCTCAATCATAACGATCTAAAAATGGTTGATAAGAAAGTCCTACGCCAATACATC
AACTACCTTCCCCAACAAGCCTATATCTTTAGTGGCTCTATCTTGGATAATCTGACTCTCGGTGCCAACCAAGCTATCAG
TCAAGAGGATATCCTAAAAGCCTGTGAAATTGCAGAAATCCGCTCGGATATTGAACAGATGCCAATGGGCTATCAGACTG
AGCTTTCTGACGGAGCTGGTCTATCTGGCGGGCAAAAACAACGGATTGCTCTTGCACGAGCTCTCTTGACCAAGGCACCT
GTGCTTATATTGGATGAAGCGACTAGCGGGCTGGATGTTCTCACCGAAAAGAAAGTCATTGACAACCTCATGGCCATGAC
AGACAAAACCATTATCTTTGTTGCTCATCGTCTCAGTATTTCCGAACGTACCAACCAAGTCATTGTGCTGGACCAGGGCA
AGATTATTGAAACCGGCTCTCACCAAGAATTAATGTCTCGCGGCGGTTTCTATCACCATTTGTTCAGTAAGTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(168-438)

ABC transporter (ABC_tran)

(500-649)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.202

98.884

0.724
  comA Streptococcus mitis NCTC 12261

68.917

99.163

0.683
  comA Streptococcus mitis SK321

68.073

99.163

0.675
  comA Streptococcus pneumoniae Rx1

67.932

99.163

0.674
  comA Streptococcus pneumoniae D39

67.932

99.163

0.674
  comA Streptococcus pneumoniae R6

67.932

99.163

0.674
  comA Streptococcus pneumoniae TIGR4

67.651

99.163

0.671
  comA Streptococcus gordonii str. Challis substr. CH1

67.37

99.163

0.668