Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   K6972_RS04985 Genome accession   NZ_CP082203
Coordinates   994561..995403 (+) Length   280 a.a.
NCBI ID   WP_222812952.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 990163..1027177 994561..995403 within 0


Gene organization within MGE regions


Location: 990163..1027177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS04955 (K6972_04955) - 990499..991272 (+) 774 WP_222812948.1 ribonuclease HII -
  K6972_RS04960 (K6972_04960) - 991275..992285 (+) 1011 WP_222812949.1 YdcF family protein -
  K6972_RS04965 (K6972_04965) - 992319..992969 (-) 651 WP_136581275.1 hemolysin III family protein -
  K6972_RS04970 (K6972_04970) - 992959..993405 (-) 447 WP_136581276.1 DUF1836 domain-containing protein -
  K6972_RS04975 (K6972_04975) - 993502..993813 (-) 312 WP_222812950.1 rhodanese-like domain-containing protein -
  K6972_RS04980 (K6972_04980) - 993943..994500 (+) 558 WP_222812951.1 sugar O-acetyltransferase -
  K6972_RS04985 (K6972_04985) dprA 994561..995403 (+) 843 WP_222812952.1 DNA-processing protein DprA Machinery gene
  K6972_RS04990 (K6972_04990) topA 995496..997589 (+) 2094 WP_024407141.1 type I DNA topoisomerase -
  K6972_RS04995 (K6972_04995) rplJ 998016..998510 (+) 495 WP_002936486.1 50S ribosomal protein L10 -
  K6972_RS05000 (K6972_05000) rplL 998576..998941 (+) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  K6972_RS05005 (K6972_05005) - 999066..999815 (+) 750 WP_222812953.1 HAD family hydrolase -
  K6972_RS05010 (K6972_05010) trmFO 1000012..1001346 (+) 1335 WP_222812954.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  K6972_RS05015 (K6972_05015) - 1001424..1002428 (+) 1005 WP_222812955.1 DNA glycosylase AlkZ-like family protein -
  K6972_RS05020 (K6972_05020) - 1002542..1003369 (+) 828 WP_024385230.1 alpha/beta hydrolase -
  K6972_RS05025 (K6972_05025) - 1003400..1004146 (+) 747 WP_024376612.1 esterase family protein -
  K6972_RS05030 (K6972_05030) - 1004164..1005330 (+) 1167 WP_222812956.1 acetyl-CoA carboxylase biotin carboxylase subunit family protein -
  K6972_RS05035 (K6972_05035) - 1005467..1005634 (-) 168 WP_169050655.1 hypothetical protein -
  K6972_RS05040 (K6972_05040) - 1005646..1006287 (-) 642 WP_024407710.1 hypothetical protein -
  K6972_RS05045 (K6972_05045) - 1006309..1006752 (-) 444 WP_024407709.1 hypothetical protein -
  K6972_RS05050 (K6972_05050) - 1007040..1007699 (-) 660 WP_222812957.1 recombinase family protein -
  K6972_RS05055 (K6972_05055) - 1008121..1008399 (-) 279 WP_024407707.1 hypothetical protein -
  K6972_RS05060 (K6972_05060) - 1008621..1009667 (-) 1047 WP_222812958.1 hypothetical protein -
  K6972_RS05065 (K6972_05065) - 1009789..1010058 (+) 270 WP_222812959.1 hypothetical protein -
  K6972_RS05070 (K6972_05070) - 1010068..1010280 (+) 213 WP_222812960.1 hypothetical protein -
  K6972_RS05075 (K6972_05075) - 1010438..1010608 (+) 171 WP_222812961.1 hypothetical protein -
  K6972_RS05080 (K6972_05080) - 1010611..1012818 (+) 2208 WP_222812962.1 type IV secretory system conjugative DNA transfer family protein -
  K6972_RS05085 (K6972_05085) - 1012901..1013701 (+) 801 WP_222812963.1 replication-relaxation family protein -
  K6972_RS05090 (K6972_05090) - 1013679..1013846 (+) 168 WP_171994911.1 hypothetical protein -
  K6972_RS05095 (K6972_05095) - 1013907..1015601 (+) 1695 WP_222812964.1 recombinase family protein -
  K6972_RS05100 (K6972_05100) - 1015771..1015911 (+) 141 WP_015646829.1 hypothetical protein -
  K6972_RS05105 (K6972_05105) - 1015924..1016313 (+) 390 WP_222812965.1 NisI/SpaI family lantibiotic immunity lipoprotein -
  K6972_RS05110 (K6972_05110) - 1016322..1017074 (+) 753 WP_024407069.1 ABC transporter ATP-binding protein -
  K6972_RS05115 (K6972_05115) - 1017075..1019045 (+) 1971 WP_158454885.1 FtsX-like permease family protein -
  K6972_RS05120 (K6972_05120) - 1019140..1019805 (+) 666 WP_158454887.1 response regulator transcription factor -
  K6972_RS05125 (K6972_05125) - 1019802..1020743 (+) 942 WP_222812966.1 sensor histidine kinase -
  K6972_RS05130 (K6972_05130) - 1020819..1022327 (+) 1509 WP_222812967.1 phosphomannomutase/phosphoglucomutase -
  K6972_RS05135 (K6972_05135) xerS 1022668..1023738 (-) 1071 WP_222812968.1 tyrosine recombinase XerS -
  K6972_RS05140 (K6972_05140) - 1023905..1024426 (-) 522 WP_024408901.1 AAA family ATPase -
  K6972_RS05145 (K6972_05145) - 1024493..1025233 (-) 741 WP_222812969.1 DUF3307 domain-containing protein -
  K6972_RS05150 (K6972_05150) - 1025237..1025905 (-) 669 WP_222812970.1 SatD family protein -
  K6972_RS05155 (K6972_05155) tnpA 1026215..1026688 (-) 474 WP_222812971.1 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31301.22 Da        Isoelectric Point: 8.6515

>NTDB_id=599932 K6972_RS04985 WP_222812952.1 994561..995403(+) (dprA) [Streptococcus suis strain NJ3]
MNNFELFKWKKAGLTNLNINKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKVYPKENKDLQTYIGKHHLVLTEYEPGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCITSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=599932 K6972_RS04985 WP_222812952.1 994561..995403(+) (dprA) [Streptococcus suis strain NJ3]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAACATTAATAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTACGCAATGTCGCTGTAGTGTCTGAATGTAAAAATCCTGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAAGAACTCAACAATCGTT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACGGCTGCCCACATCGCCAGTCTGAAAAATGGAGGCCAAACCATT
GCTGTAATTGGAACAGGTTTGGATAAGGTCTATCCCAAAGAAAACAAGGACTTGCAGACCTACATTGGCAAACACCATTT
AGTATTAACAGAGTATGAACCGGGTGCCCAGCCACTCAAATACCATTTCCCAGAACGTAACCGCATCATTGCTGGGTTGG
TAGAAGGTCTGGTGGTTTGCGAGGCAAAAATGCGGTCTGGTAGCTTGATTACTTGCGAACGTGCCTTGGAAGAAGGAAGG
GAAGTCTATGCCATTCCTGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGGGCAAAGTG
CATCACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

70

100

0.7
  dprA/cilB/dalA Streptococcus mitis SK321

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.929

100

0.639
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.214

100

0.632
  dprA Lactococcus lactis subsp. cremoris KW2

59.643

100

0.596
  dprA Bacillus subtilis subsp. subtilis str. 168

51.244

71.786

0.368
  dprA Legionella pneumophila strain ERS1305867

40.891

88.214

0.361