Detailed information NTG0599919

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: K6972_RS01040
• Genome accession: NZ_CP082203
• Coordinates: 161845..162279 (+)
• Length: 144 a.a.
• NCBI ID: WP_024407345.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NJ3
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 156845..167279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6972_RS00990 (K6972_00990)	-	157564..157827 (+)	264	WP_024410576.1	hypothetical protein	-
K6972_RS00995 (K6972_00995)	-	157840..158295 (+)	456	WP_016056164.1	hypothetical protein	-
K6972_RS01000 (K6972_01000)	-	158270..158473 (+)	204	WP_016056163.1	putative holin protein	-
K6972_RS01005 (K6972_01005)	-	158603..159313 (+)	711	WP_016056162.1	CHAP domain-containing protein	-
K6972_RS01010 (K6972_01010)	prx	159461..159646 (+)	186	WP_016056161.1	hypothetical protein	Regulator
K6972_RS01015 (K6972_01015)	-	159671..159973 (+)	303	Protein_168	ATPase, T2SS/T4P/T4SS family	-
K6972_RS01020 (K6972_01020)	comYB	159885..160922 (+)	1038	WP_261984178.1	competence type IV pilus assembly protein ComGB	Machinery gene
K6972_RS01025 (K6972_01025)	comYC	160924..161205 (+)	282	WP_114866111.1	competence type IV pilus major pilin ComGC	Machinery gene
K6972_RS01030 (K6972_01030)	comGD	161186..161593 (+)	408	WP_114866112.1	competence type IV pilus minor pilin ComGD	-
K6972_RS01035 (K6972_01035)	comYE	161565..161858 (+)	294	WP_205026479.1	competence type IV pilus minor pilin ComGE	Machinery gene
K6972_RS01040 (K6972_01040)	comGF/cglF	161845..162279 (+)	435	WP_024407345.1	competence type IV pilus minor pilin ComGF	Machinery gene
K6972_RS01045 (K6972_01045)	comGG	162257..162667 (+)	411	WP_114866114.1	competence type IV pilus minor pilin ComGG	-
K6972_RS01050 (K6972_01050)	comYH	162724..163677 (+)	954	WP_024414316.1	class I SAM-dependent methyltransferase	Machinery gene
K6972_RS01055 (K6972_01055)	-	163727..164914 (+)	1188	WP_114866116.1	acetate kinase	-
K6972_RS01060 (K6972_01060)	-	165230..165781 (+)	552	WP_074391332.1	folate family ECF transporter S component	-
K6972_RS01065 (K6972_01065)	-	165837..167093 (+)	1257	WP_222812628.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16357.67 Da
• Isoelectric Point: 7.1649

>NTDB_id=599919 K6972_RS01040 WP_024407345.1 161845..162279(+) (comGF/cglF) [Streptococcus suis strain NJ3]
MLKSKIPAFTLLECLVALVILSGSLLVFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQADLVKVENGKVYVDKGG
QALAFGKSRSDDFRKTNDRGQGYQPMLYHLDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=599919 K6972_RS01040 WP_024407345.1 161845..162279(+) (comGF/cglF) [Streptococcus suis strain NJ3]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCCTTAGTCATTCTTTCAGGTAGTCTTCTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGTCAATTGCGGTCGGAGTGGGACCAGGCTGACTTGGTCAAGGTTGAAAATGGCAAGGTCTATGTTGATAAGGGAGGG
CAGGCTTTGGCCTTTGGTAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGAGGACAGGGCTACCAGCCCATGCT
CTATCATCTAGACAGCGCAGCTATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAATGGAGAGGAGC
GGACTTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	54.61	97.917	0.535
comGF/cglF	Streptococcus pneumoniae Rx1	54.61	97.917	0.535
comGF/cglF	Streptococcus pneumoniae D39	54.61	97.917	0.535
comGF/cglF	Streptococcus pneumoniae R6	54.61	97.917	0.535
comGF/cglF	Streptococcus mitis NCTC 12261	55.224	93.056	0.514
comYF	Streptococcus mutans UA140	50	100	0.5
comYF	Streptococcus mutans UA159	49.306	100	0.493
comGF/cglF	Streptococcus mitis SK321	52.239	93.056	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.518	97.917	0.465