Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   K6976_RS07740 Genome accession   NZ_CP082202
Coordinates   1580422..1581126 (-) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain SS389     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1575422..1586126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS07725 (K6976_07725) vga(F) 1576525..1577910 (-) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -
  K6976_RS07730 (K6976_07730) vicX 1578270..1579073 (-) 804 WP_014637679.1 MBL fold metallo-hydrolase Regulator
  K6976_RS07735 (K6976_07735) micB 1579080..1580429 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  K6976_RS07740 (K6976_07740) micA 1580422..1581126 (-) 705 WP_002935840.1 response regulator YycF Regulator
  K6976_RS07745 (K6976_07745) - 1581320..1582081 (+) 762 WP_172005595.1 amino acid ABC transporter ATP-binding protein -
  K6976_RS07750 (K6976_07750) - 1582092..1582931 (+) 840 WP_222759206.1 transporter substrate-binding domain-containing protein -
  K6976_RS07755 (K6976_07755) - 1582946..1583644 (+) 699 WP_024401921.1 amino acid ABC transporter permease -
  K6976_RS07760 (K6976_07760) - 1583659..1584318 (+) 660 WP_024401920.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=599890 K6976_RS07740 WP_002935840.1 1580422..1581126(-) (micA) [Streptococcus suis strain SS389]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=599890 K6976_RS07740 WP_002935840.1 1580422..1581126(-) (micA) [Streptococcus suis strain SS389]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTAGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376